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Dihydrolipoyllysine-Residue Acetyltransferase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the acetyltransferase reaction using ACETYL CoA as an acetyl donor and dihydrolipoamide as acceptor to produce COENZYME A (CoA) and S-acetyldihydrolipoamide. It forms the (E2) subunit of the PYRUVATE DEHYDROGENASE COMPLEX.      Other names Transacetylase, Dihydrolipoyl; S-Acetyltransferase, Dihydrolipoamide; S-Acetyltransferase, Acetyl-CoA-Dihydrolipoamide; Dihydrolipoyllysine Residue Acetyltransferase; Dihydrolipoamide S Acetyltransferase; Acetyltransferase, Dihydrolipoyllysine-Residue; Acetyltransferase, Dihydrolipoyl; Acetyltransferase, Lipoate; Acetyltransferase, Dihydrolipoamide; Acetyl CoA Dihydrolipoamide S Acetyltransferase; Pyruvate Dehydrogenase Complex E2; Lipoate Acetyltransferase; Dihydrolipoyl Transacetylase; Dihydrolipoyl Acetyltransferase; Dihydrolipoamide S-Acetyltransferase; Dihydrolipoamide Acetyltransferase; Acetyl-CoA-Dihydrolipoamide S-Acetyltransferase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PDA2 protein, S cerevisiae  EC 2.3.1.12   *Saccharomyces cerevisiae Proteins *Dihydrolipoyllysine-Residue Acetyltransferase.
Dlat protein, mouse  EC 2.3.1.12   *Mitochondrial Proteins *Dihydrolipoyllysine-Residue Acetyltransferase.
Dlat protein, rat  EC 2.3.1.12   *Autoantigens *Mitochondrial Proteins *Dihydrolipoyllysine-Residue Acetyltransferase.
MRP-3 protein, Neurospora crassa  135640-68-5   *Fungal Proteins *Ribosomal Proteins *Dihydrolipoyllysine-Residue Acetyltransferase. J Biol Chem 1991;266(5):2843
DLAT protein, human  EC 2.3.1.12   *Autoantigens *Mitochondrial Proteins *Dihydrolipoyllysine-Residue Acetyltransferase. J Immunol 1987;138(10):3525

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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