Definition: A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Other names Wiskott Aldrich Syndrome Protein Family, Member 3; Wiskott Aldrich Syndrome Protein Family, Member 2; Wiskott Aldrich Syndrome Protein Family, Member 1; Wiskott Aldrich Syndrome Protein Family; WASP Family Verprolin Homologous Proteins; Wiskott-Aldrich Syndrome Protein Family, Member 3; Wiskott-Aldrich Syndrome Protein Family, Member 2; Wiskott-Aldrich Syndrome Protein Family, Member 1; WAVE3 Protein; WAVE2 Protein; WAVE1 Protein; WASP Protein Family; WASF3 Protein; WASF2 Protein; WASF1 Protein; WAS Protein Family, Member 3; WAS Protein Family, Member 2; WAS Protein Family, Member 1; WAVE Proteins; WASP-Family Verprolin Homologous Proteins
