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Paired Box Transcription Factors

More information in Books or onNLM PubMed
Definition: A family of transcription factors that control EMBRYONIC DEVELOPMENT within a variety of cell lineages. They are characterized by a highly conserved paired DNA-binding domain that was first identified in DROSOPHILA segmentation genes.     
Examples B-Cell-Specific Activator Protein; PAX2 Transcription Factor; PAX7 Transcription Factor; PAX9 Transcription Factor 		Other names Transcription Factors, Pax; Pax Transcription Factors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Vab3 protein, C elegans  0   *Caenorhabditis elegans Proteins *Paired Box Transcription Factors. Nature 1995 Sep 7;377(6544):52-5
PAX7 protein, rat  0   *Paired Box Transcription Factors. Muscle Nerve. 2008 Jul;38(1):861-6
PAX3 protein, rat  0   *Paired Box Transcription Factors. Muscle Nerve. 2008 Jul;38(1):861-6
Pax8 protein, Xenopus  0   *Xenopus Proteins *Paired Box Transcription Factors.
Pax8 protein, rat  0   *Paired Box Transcription Factors.
Pax8 protein, mouse  0   *Paired Box Transcription Factors.
Pax8 protein, Canis familiaris  0   *Paired Box Transcription Factors.
Pax8 protein, zebrafish  0   *Zebrafish Proteins *Paired Box Transcription Factors. Development 2004 Oct;131(20):5091-102
PAX4 protein, human  0   *Homeodomain Proteins *Paired Box Transcription Factors Repressor Proteins.
Pax4 protein, rat  0   *Homeodomain Proteins *Paired Box Transcription Factors Repressor Proteins.
pax3 protein, zebrafish  0   *Zebrafish Proteins *Paired Box Transcription Factors.
Pax3 protein, Xenopus  0   *Xenopus Proteins *Paired Box Transcription Factors.
PAX3 protein, human  0   *Paired Box Transcription Factors.
Pax9 protein, mouse  0   *Paired Box Transcription Factors. Dev Biol 1995 Aug;170(2):701-16
PAX3-FOXO1A fusion protein, human  0   *Oncogene Proteins, Fusion *Paired Box Transcription Factors. Cancer Genet Cytogenet 2003 Jan 1;140(1):73-7
Pax-B protein, Podocoryne carnea  0   *Homeodomain Proteins *Paired Box Transcription Factors. Mech Dev 2000 Jun;94(1-2):157-69
pax19 protein, invertebrate  0   *Paired Box Transcription Factors. Development 1999 Jun;126(11):2539-50
Amphipax-6 protein, Branchiostoma floridae  0   *Eye Proteins *Paired Box Transcription Factors. Development 1998 Jul;125(14):2701-10
Pax4 protein, mouse  0   *Homeodomain Proteins *Paired Box Transcription Factors Repressor Proteins. Biochem Biophys Res Commun 1998 Jan 6;242(1):176-80
PAX-37 protein, Halocynthia roretzi  0   *Nerve Tissue Proteins *Paired Box Transcription Factors Antigens, Differentiation. Dev Biol 1997 Jul 15;187(2):240-52
homeobox protein PITX1  0   *Paired Box Transcription Factors Nerve Tissue Proteins Repressor Proteins Xenopus Proteins. Genes Dev 1996 May 15;10(10):1284-95; Proc Natl Acad Sci U S A 1996 Jul 23;93(15):7706-10
PAX6 protein  0   *Eye Proteins *Repressor Proteins *Homeodomain Proteins *Paired Box Transcription Factors. Hum Mol Genet 1993 Dec;2(12):2093-7
PAX8 protein, human  0   *Paired Box Transcription Factors. Biochim Biophys Acta 1996 Jun 3;1307(1):97-103; Mol Cell Biol 1993 Oct;13(10):6024-35
Poxn protein, Drosophila  0   *Nerve Tissue Proteins *Drosophila Proteins *Paired Box Transcription Factors. Cell 1992 Apr 3;69(1):159-72
PAX1 transcription factor  142661-96-9   *Paired Box Transcription Factors. Cell 1991;66(5):873
Pax3 protein, mouse  138016-91-8   *Paired Box Transcription Factors. Embo J 1991;10(5):1135

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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