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Smad Proteins

More information in Books or onNLM PubMed
Definition: A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.  general; prefer specifics   
Examples Smad Proteins, Inhibitory; Smad Proteins, Receptor-Regulated; Smad4 Protein 		Other names Sma- and Mad-Related Proteins; Mothers Against Decapentaplegic Homolog
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Xmad1 protein, Xenopus  0   *Xenopus Proteins *Smad Proteins.
DAF-14 protein, C elegans  0   *Caenorhabditis elegans Proteins *Smad Proteins Signal Transduction Transforming Growth Factor beta. Dev Biol 2000 Jan 1;217(1):192-204
Smad10 protein, Xenopus  0   *Nerve Growth Factors *Xenopus Proteins *Smad Proteins Embryonic Induction. Development 1999 Jan;126(1):137-46
DAF-3 protein, C elegans  0   *Caenorhabditis elegans Proteins *Smad Proteins Signal Transduction Transforming Growth Factor beta. Genes Dev 1997 Oct 15;11(20):2679-90

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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