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Inhibitor of Differentiation Proteins
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Definition
: Inhibitor of differentiation proteins are negative regulators of BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS. They inhibit CELL DIFFERENTIATION and induce CELL PROLIFERATION by modulating different CELL CYCLE regulators.
Examples
Inhibitor of Differentiation Protein 1
;
Inhibitor of Differentiation Protein 2
Other names
Differentiation Proteins Inhibitor; ID DNA Binding Protein Inhibitor
Substance
CAS Registry & name
Categories
Source
Drugs
*
Id3 protein, Xenopus
0
*Xenopus Proteins
*Inhibitor of Differentiation Proteins
Helix-Loop-Helix Motifs.
Development 2005 Apr;132(8):1831-41
Id3 protein, rat
0
*Inhibitor of Differentiation Proteins
Helix-Loop-Helix Motifs.
Circ Res 2004 Sep 17;95(6):557-9
ID4 protein, human
0
*Inhibitor of Differentiation Proteins
Helix-Loop-Helix Motifs.
Id4 protein, Xenopus
0
*Xenopus Proteins
*Inhibitor of Differentiation Proteins
Helix-Loop-Helix Motifs.
Idb4 protein, rat
0
*Inhibitor of Differentiation Proteins
Helix-Loop-Helix Motifs.
Idb4 protein, mouse
0
*Inhibitor of Differentiation Proteins
Helix-Loop-Helix Motifs.
Nucleic Acids Res 1994 Mar 11;22(5):749-55
ID3 protein, human
147785-34-0
*Neoplasm Proteins
*Inhibitor of Differentiation Proteins
Neuroblastoma
Helix-Loop-Helix Motifs.
EMBO J 1992 Jul;11(7):2563-71
Idb3 protein, mouse
135845-89-5
*Inhibitor of Differentiation Proteins
Helix-Loop-Helix Motifs.
Proc Natl Acad Sci USA 1991;88(5):1815