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Antigens, CD86

More information in Books or onNLM PubMed
Definition: A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.      Other names Costimulatory Molecule, B70; Costimulatory Molecule, B7-2; B7 2 Antigen; Antigen, CD86; Antigen, B7 2; Early T Cell Costimulatory Molecule 1; CD86 Antigen; B70 Costimulatory Molecule; B7-2 Antigen; Antigen, B7-2; CD86 Antigens; B7-2 Costimulatory Molecule
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Cd86 protein, rat  0   *Antigens, CD86.
Cd86 protein, mouse  0   *Antigens, CD86.
CD86 protein, human  0   *Antigens, CD86.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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