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Osteoprotegerin

More information in Books or onNLM PubMed
Definition: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.      Other names Follicular Dendritic Cell Derived Receptor 1; FDCR 1 Protein; Tumor Necrosis Factor Receptor 11b; OCIF Protein; Follicular Dendritic Cell-Derived Receptor-1; FDCR-1 Protein; Tumor Necrosis Factor Receptor Superfamily, Member; Receptors, Tumor Necrosis Factor, Member 11b; Osteoclastogenesis Inhibitory Factor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tnfrsf11b protein, rat  0   *Osteoprotegerin.
Tnfrsf11b protein, mouse  0   *Osteoprotegerin.
TNFRSF11B protein, human  0   *Osteoprotegerin.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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