Definition: An interleukin-1 receptor subtype that competes with the INTERLEUKIN-1 RECEPTOR TYPE I for binding to INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The interleukin-1 type II receptor appears to lack signal transduction capability. Therefore it may act as a "decoy" receptor that modulates the activity of its ligands. Both membrane-bound and soluble forms of the receptor have been identified.
Other names Receptors, Interleukin 1 Type II; Interleukin 1 Receptors Type II; Interleukin 1 Receptor, Type 2; Interleukin 1 Receptor Type II; Interleukin-1 Receptors Type II; Interleukin-1 Receptor, Type 2; Interleukin-1 Receptor Type II; CDw121b Antigens; Antigens, CDw121b