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Receptors, Interleukin-1 Type II

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Definition: An interleukin-1 receptor subtype that competes with the INTERLEUKIN-1 RECEPTOR TYPE I for binding to INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The interleukin-1 type II receptor appears to lack signal transduction capability. Therefore it may act as a "decoy" receptor that modulates the activity of its ligands. Both membrane-bound and soluble forms of the receptor have been identified.      Other names Receptors, Interleukin 1 Type II; Interleukin 1 Receptors Type II; Interleukin 1 Receptor, Type 2; Interleukin 1 Receptor Type II; Interleukin-1 Receptors Type II; Interleukin-1 Receptor, Type 2; Interleukin-1 Receptor Type II; CDw121b Antigens; Antigens, CDw121b
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
IL1R2 protein, human  0   *Receptors, Interleukin-1 Type II.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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