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TYK2 Kinase

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Definition: A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.      Other names Non Receptor Tyrosine Protein Kinase TYK2; Tyrosine Kinase 2; Non-Receptor Tyrosine-Protein Kinase TYK2; Kinase, TYK2
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tyk2 protein, rat  EC 2.7.1.112   *TYK2 Kinase.
Tyk2 protein, mouse  EC 2.7.1.112   *TYK2 Kinase.
TYK2 protein, human  EC 2.7.1.112   *TYK2 Kinase. Oncogene 1991;6(7):1185

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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