Transforming Growth Factor beta2 (definition)

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Transforming Growth Factor beta2

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Definition: A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.

Other names TGF beta2LAP; TGF beta2 Latency Associated Protein; Latency-Associated Protein, TGF-beta2; Glioblastoma Derived T Cell Suppressor Factor; Cartilage Inducing Factor B; BSC 1 Cell Growth Inhibitor; Transforming Growth Factor beta 2 Latency Associat; TGF-beta2 Latency-Associated Protein; TGF-beta-2; Suppressor Factor, T-Cell, Glioblastoma-Derived; TGF-beta2LAP; Polyergin; Glioblastoma-Derived T-Cell Suppressor Factor; Cartilage-Inducing Factor-B; BSC-1 Cell Growth Inhibitor; TGF-beta2

Substance	CAS Registry & name	Categories	Source	Drugs*
Tgfb2 protein, rat	0	*Transforming Growth Factor beta2.
Tgfb2 protein, mouse	0	*Transforming Growth Factor beta2.
TGFB2 protein, human	0	*Transforming Growth Factor beta2.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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