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Receptor-Like Protein Tyrosine Phosphatases

More information in Books or onNLM PubMed
Definition: A subcategory of protein tyrosine phosphatases that are bound to the cell membrane. They contain cytoplasmic tyrosine phosphatase domains and extracellular protein domains that may play a role in cell-cell interactions by interacting with EXTRACELLULAR MATRIX components. They are considered receptor-like proteins in that they appear to lack specific ligands.     
Examples Receptor-Like Protein Tyrosine Phosphatases, Class 1; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Receptor-Like Protein Tyrosine Phosphatases, Class 7; Receptor-Like Protein Tyrosine Phosphatases, Class 8 		Other names Receptor Like Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Receptor Like; Protein Tyrosine Phosphatases, Receptor-Like
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
liprin-alpha4 protein, human  EC 3.1.3.48   *Receptor-Like Protein Tyrosine Phosphatases. Exp Cell Res 2010 Oct 15;316(17):2883-92
CRYPalpha protein, Gallus gallus  EC 3.1.3.48   *Avian Proteins *Receptor-Like Protein Tyrosine Phosphatases Cell Adhesion Molecules.
PTP69D protein, Drosophila  EC 3.1.3.48   *Drosophila Proteins *Receptor-Like Protein Tyrosine Phosphatases. Genetics 2003 Jun;164(2):575-88
Lar protein, Drosophila  EC 3.1.3.48   *Drosophila Proteins *Receptor-Like Protein Tyrosine Phosphatases. Neuron 1999 Feb;22(2):301-12
CLR-1 protein, C elegans  EC 3.1.3.48   *Caenorhabditis elegans Proteins *Receptor-Like Protein Tyrosine Phosphatases. Genes Dev 1998 May 15;12(10):1425-37
CRYPalpha protein, Xenopus  EC 3.1.3.48   *Xenopus Proteins *Receptor-Like Protein Tyrosine Phosphatases Cell Adhesion Molecules. Development 1995 Jun;121(6):1833-44

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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