Phosphoinositide Phospholipase C (definition)

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Phosphoinositide Phospholipase C

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Definition: A type C phospholipase with specificity towards PHOSPHATIDYLINOSITOLS that contain INOSITOL 1,4,5-TRISPHOSPHATE. Many of the enzymes listed under this classification are involved in intracellular signaling.

Examples Phospholipase C beta; Phospholipase C delta; Phospholipase C gamma

Other names PIP2-PLC; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodie; 1-Phosphatidyl-D-myo-Inositol-4,5-bisphosphate Ino; Tri phosphoinositide Phosphodiesterase; Phospholipase C, Polyphosphoinositide; Phospholipase C, Phosphatidylinositol-Specific; Phospholipase C, Phosphatidylinositide-4,5-Bisphos; Phosphodiesterase, Triphosphoinositide; Phosphodiesterase, Polyphosphoinositide; Phosphodiesterase, PPI; Phosphodiesterase, 1-Phosphatidylinositol-4,5-Bisp; Phosphatidylinositol Specific Phospholipase C; Phosphatidylinositol 4,5 Biphosphate Phosphodieste; Phosphatidylinositide 4,5 Bisphosphate Phospholipa; PIP2 Phosphoinositidase C; Inositoltrisphosphohydrolase, 1-Phosphatidyl-D-myo; 1 Phosphatidylinositol 4,5 Bisphosphate Phosphodie; 1 Phosphatidyl D myo Inositol 4,5 bisphosphate Ino; Triphosphoinositide Phosphodiesterase; Tri-phosphoinositide Phosphodiesterase

Substance	CAS Registry & name	Categories	Source
PLCH2 protein, human	EC 3.1.4.3	*Phosphoinositide Phospholipase C.	Biochem J 2005 Nov 1;391(Pt 3):667-76
Plch1 protein, mouse	EC 3.1.4.3	*Phosphoinositide Phospholipase C.	Biochem J 2005 Jul 1;389(Pt 1):181-6
PLCH1 protein, human	EC 3.1.4.11	*Phosphoinositide Phospholipase C.	Biochem J 2005 Jul 1;389(Pt 1):181-6
Plch2 protein, mouse	EC 3.1.4.3	*Phosphoinositide Phospholipase C.	J Biol Chem 2005 Aug 12;280(32):29128-34
PLCZ1 protein, human	EC 3.1.4.11	*Phosphoinositide Phospholipase C.
Plcz1 protein, mouse	EC 3.1.4.3	*Phosphoinositide Phospholipase C.
plc-1 protein, C elegans	EC 3.1.4.11	Caenorhabditis elegans Proteins Phosphoinositide Phospholipase C.
phospholipase C epsilon	EC 3.1.4.11	*Phosphoinositide Phospholipase C.	EMBO J 2001 Feb 15;20(4):743-54

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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