encyclopedia of medical concepts
ψ 
ψ 
ψ 

Nodal Signaling Ligands

More information in Books or onNLM PubMed
Definition: Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE.     
Examples Growth Differentiation Factor 1; Growth Differentiation Factor 3; Left-Right Determination Factors; Nodal Protein 		Other names Signaling Proteins, Nodal; Nodal Signaling Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ndr1 protein, zebrafish  0   *Zebrafish Proteins *Nodal Signaling Ligands Transforming Growth Factor beta. Nature 1998 Sep 10;395(6698):181-5
Xnr6 protein, Xenopus  0   *Xenopus Proteins *Nodal Signaling Ligands. Development 2000 Dec;127(24):5319-29
Xnr5 protein, Xenopus  0   *Xenopus Proteins *Nodal Signaling Ligands. Development 2000 Dec;127(24):5319-29

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy