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Group II Chaperonins

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Definition: A subcategory of chaperonins found in ARCHAEA and the CYTOSOL of eukaryotic cells. Group II chaperonins form a barrel-shaped macromolecular structure that is distinct from GROUP I CHAPERONINS in that it does not utilize a separate lid like structure to enclose proteins.     
Examples Chaperonin Containing TCP-1; Thermosomes 		Other names Chaperonins, Type II; Chaperonins, Group II; Chaparonins, Group II; Type II Chaperonins; Group II Chaparonins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
BBS12 protein, human  0   *Group II Chaperonins. Am J Hum Genet 2007 Jan;80(1):1-11
BBS10 protein, human  0   *Group II Chaperonins. Nat Genet 2006 May;38(5):521-4
Mkks protein, mouse  0   *Group II Chaperonins. Nat Genet 2000 May;25(1):79-82
cct-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Group II Chaperonins.
MKKS protein, human  0   *Group II Chaperonins. Nat Genet 2000 Sep;26(1):67-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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