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Enzyme Replacement Therapy

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Definition: Therapeutic replacement or supplementation of defective or missing enzymes to alleviate the effects of enzyme deficiency (e.g., GLUCOSYLCERAMIDASE replacement for GAUCHER DISEASE).  coordinate with specific enzyme / ther use    Other names Therapy, Enzyme Replacement; Therapies, Enzyme Replacement; Replacement Therapy, Enzyme; Replacement Therapies, Enzyme; Enzyme Replacement Therapies
 
SubstanceCAS Registry & nameCategoriesSource
asfotase alfa  0   *Alkaline Phosphatase *Immunoglobulin G *Recombinant Fusion Proteins Hypophosphatasia/drug therapy Enzyme Replacement Therapy. N Engl J Med. 2012 Mar 8;366(10):904-13
alglucerase  EC 3.2.1.-   *Glucosylceramidase Gaucher Disease Enzyme Replacement Therapy. Med Lett Drugs Ther 1991;33(851):82CEREDASE

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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