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Nuclear Receptor Subfamily 2, Group C, Member 1

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Definition: A DNA-binding orphan nuclear receptor that has specificity for directly repeated (DR) AGGTCA sequences. It binds DNA as either as a homodimer or as a heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2. The protein was originally identified as a PROSTATE-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.      Other names TR2 11 Receptor; Receptor TR2, Nuclear; TR2-11 Receptor; Orphan Nuclear Receptor TR2; Orphan Nuclear Receptor NR2C1; Nuclear Receptor TR2; Nuclear Receptor NR2C1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Nr2c1 protein, rat  0   *Nuclear Receptor Subfamily 2, Group C, Member 1.
Nr2c1 protein, mouse  0   *Nuclear Receptor Subfamily 2, Group C, Member 1.
NR2C1 protein, human  0   *Nuclear Receptor Subfamily 2, Group C, Member 1.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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