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Tetraspanins

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Definition: A large superfamily of cell surface membrane proteins characterized by their four transmembrane domains. They play a role in a variety of processes such as cellular adhesion and motility. They may be involved in the organization of cell surface MEMBRANE MICRODOMAINS that regulate the activation of LEUKOCYTES.  general or unspecified; prefer specifics   
Examples Antigens, CD9; Antigens, CD53; Antigens, CD63; Antigens, CD81; Antigens, CD82; Antigens, CD151; Uroplakin Ia; Uroplakin Ib
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TSPAN5 protein, human  0   *Tetraspanins.
TSPAN18 protein, human  0   *Tetraspanins.
TSPAN17 protein, human  0   *Tetraspanins.
TSPAN15 protein, human  0   *Tetraspanins.
TSPAN14 protein, human  0   *Tetraspanins.
TM4SF18 protein, human  0   *Tetraspanins.
TSPAN11 protein, human  0   *Tetraspanins.
TSPAN10 protein, human  0   *Tetraspanins.
TSPAN12 protein, human  0   *Tetraspanins. FASEB J 2009 Nov;23(11):3674-81
Tspan12 protein, mouse  0   *Tetraspanins. Cell 2009 Oct 16;139(2):299-311
TSPAN9 protein, human  0   *Tetraspanins. Biochem J 2009 Jan 1;427(1):391-400
Tspan13 protein, mouse  0   *Tetraspanins. Allergol Int. 2007 Dec;56(4):457-63
tspan1 protein, Xenopus  0   *Xenopus Proteins *Tetraspanins. Differentiation. 2007 Mar;75(3):235-45
TSPAN16 protein, human  0   *Tetraspanins.
ROM1 protein, human  0   *Tetraspanins.
Tspan2 protein, rat  0   *Nerve Tissue Proteins *Tetraspanins.
Tspan2 protein, mouse  0   *Nerve Tissue Proteins *Tetraspanins.
TSPAN2 protein, human  0   *Nerve Tissue Proteins *Tetraspanins.
TSPAN1 protein, human  0   *Tetraspanins. BMC Cancer 2005;5():111
TSPAN33 protein, human  0   *Tetraspanins. Cancer Genet Cytogenet. 2005 Oct 15;162(2):95-8
Cd37 protein, mouse  0   *Antigens, Neoplasm *Antigens, CD *Tetraspanins.
Cd37 protein, rat  0   *Antigens, Neoplasm *Antigens, CD *Tetraspanins.
TSPAN13 protein, human  0   *Tetraspanins. Clin Cancer Res. 2005 Jun 15;11(12):4357-64
Tspan3 protein, rat  0   *Nerve Tissue Proteins *Tetraspanins. J Neurosci Res 2004 Jul 15;77(2):166-73
Upk1b protein, mouse  0   *Tetraspanins.
Upk1a protein, mouse  0   *Tetraspanins.
TSPAN32 protein, human  0   *Tetraspanins.
Tspan5 protein, mouse  0   *Tetraspanins. Mech Dev 2001 Aug;106(1-2):207-12
Tspan3 protein, mouse  0   *Tetraspanins. J Cell Biol 2001 Apr 16;153(2):
TSPAN7 protein, human  0   *Nerve Tissue Proteins *Tetraspanins. Nat Genet 2000 Feb;24(2):167-70
TSPAN6 protein, human  0   *Tetraspanins. Genomics 1998 Sep 1;52(2):240-2
Tspan8 protein, rat  0   *Tetraspanins. J Cell Biol 1998 Apr 6;141(1):267-80
TSPAN4 protein, human  0   *Tetraspanins Antigens, Surface Nerve Tissue Proteins. J Biol Chem 1997 Nov 14;272(46):29181-9
TSPAN31 protein, human  0   *Tetraspanins. Oncogene 1994 Apr;9(4):1205-11
TSPAN8 protein, human  0   *Tetraspanins. Proc Natl Acad Sci USA 1990;87(17):6833
CD37 protein, human  0   *Antigens, Neoplasm *Tetraspanins. J Exp Med 1989;169(4):1497

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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