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V-Set Domain-Containing T-Cell Activation Inhibitor 1

More information in Books or onNLM PubMed
Definition: A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION.      Other names V Set Domain Containing T Cell Activation Inhibito; T Cell Costimulatory Molecule B7x; Immune Costimulatory Protein B7 H4; T-Cell Costimulatory Molecule B7x; Immune Costimulatory Protein B7-H4; B7H4 Immune Costimulatory Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
VTCN1 protein, human  0   *V-Set Domain-Containing T-Cell Activation Inhibitor 1. Immunity 2003 Jun;18(6);863-73
Vtcn1 protein, mouse  0   *V-Set Domain-Containing T-Cell Activation Inhibitor 1. Immunity 2003 Jun;18(6);849-61

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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