Definition: A NADP transhydrogenase subtype found in certain types of BACTERIA and mammalian MITOCHONDRIA. This transhydrogenase uses a mechanism that can transfer hydrogen to either side, A or B, of the NAD(+) or NADP(+) ring structure. In heart mitochondria, the enzyme is A-specific with respect to NAD(+) and B-specific with respect to NADP(+).
Other names Pyridine nucleotide transhydrogenase, AB Specific; NADP Transhydrogenase, AB Specific; AB-Specific NADP Transhydrogenase; Pyridine nucleotide transhydrogenase, AB-Specific
