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ψ
wortmannin
under Androstadienes
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Androstadienes
Definition
: Derivatives of the steroid androstane having two double bonds at any site in any of the rings.
Substance
CAS Registry & name
Categories
Source
Drugs
*
wortmannin [ MS 54,MS-54 ]
inhibits PI3-kinase; inhibits alloantigen-specific T cell activation and cytotoxic T cell responses in human tumor cell lines
19545-26-7 (1 alpha,11 alpha)-
11-
(acetyloxy)-
1-
(methoxymethyl)-
2-
oxaandrosta-
5,8-
dieno(6,5,4-
bc)furan-
3,7,17-
trione
*Androstadienes
Mycotoxins
Phosphatidylinositol 3-Kinases/antagonists & inhibitors
Pharma Action
Antifungal Agents
;
Immunosuppressive Agents
;
Insulin Antagonists
;
Phosphodiesterase Inhibitors
;
Radiation-Sensitizing Agents
;
Serotonin Antagonists
;
Protein Kinase Inhibitors
Helv Chim Acta 56(1):2901;1973; J Chem Soc Perkin I 2892;1972