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domoic acid

under Kainic Acid
More information in Books or onNLM PubMed
More on Kainic Acid Definition: (2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.  an antinematodal agent & excitatory amino acid agonist    Other names Digenic Acid; Acid, Kainic; Acid, Digenic; Kainate
SubstanceCAS Registry & nameCategoriesSourceDrugs*
domoic acid [ 2 alpha-carboxy-4 beta-(5-carboxy-1-methyl-1,3 beta-hexadienyl)-3-pyrrolidineacetic acid,domoate,domoic acid, sodium salt ]
  kainic acid analog, heterocyclic amino acid from seaweed; RN given refers to parent cpd; structure 		14277-97-5 3-pyrrolidineacetic acid, 2-carboxy-4-(5-carboxy-1-methyl-1,3-hexadienyl)-, (2S-(2 alpha,3 beta,4 beta(1E,3E,5R*)))  Kainic Acid/*analogs & derivatives Marine Toxins Neurotoxins
Pharma Action Neuromuscular Depolarizing Agents 		Neuropharmacol 15(2):145;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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