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vinpocetine

under Vinca Alkaloids
More information in Books or onNLM PubMed
More on Vinca Alkaloids Definition: A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.      Other names Alkaloids, Vinca
SubstanceCAS Registry & nameCategoriesSourceDrugs*
vinpocetine [ Armstrong brand of vinpocetine,Cavinton,Celltech brand of vinpocetine,Kavinton,RGH-4405,TCV-3B,ethyl apovincaminate,ethyl apovincaminate tartrate (1:1),ethyl apovincaminate, (+-)-isomer,ethyl apovincaminate, (16alpha)-isomer,ethyl apovincaminate, (3alpha,16alpha)-isomer,ethyl apovincaminate, 2-oxopentanedioate (1:1),ethyl apovincaminate, 3H-labeled ]
  whole issue of Arzneim Forsch (23 articles) discuss this drug; Arzneim Forsch 26(10a);1976; RN given refers to parent cpd with unspecified isomeric designation 		42971-12-0 eburnamenine-14-carboxylic acid, ethyl ester, (3 alpha,16 alpha)  *Vinca Alkaloids Anticonvulsants Antihypertensive Agents Calcium Channel Blockers
Pharma Action Phosphodiesterase Inhibitors; Vasodilator Agents; Neuroprotective Agents; Nootropic Agents 		Acta Pharm Hung 48(suppl):54;1978; Arch Int Pharmacodyn 226:139;1977; Arzneim Forsch 1979;29(6):953; Arzneim Forsch 1979;29(6):957; Arzneim Forsch 26(10a):1907;1976; Br J Clin Pharmacol 1980;9(1):100; Ther Hung 1979;21(1):15; Ther Hung 1979;27(1):17; Ther Hung 1979;27(1):29; Ther Hung 1979;27(4):182; Ther Hung 26(1):16;1978; Ther Hung 26(4):181;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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