encyclopedia of medical concepts
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ecarin

under Endopeptidases
More information in Books or onNLM PubMed
More on Endopeptidases Definition: A subclass of PEPTIDE HYDROLASES that catalyze the internal cleavage of PEPTIDES or PROTEINS.      Other names Peptide Peptidohydrolases
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ecarin [ Echis carinatus prothrombin-activating proteins,echarin,prothrombin activation fragments, ecarin,prothrombin activator (Echis carinatus venom) ]
  cleaves specifically Arg-Ile bond in prothrombin; procoagulant enzyme from Echis carinatus venom which converts prothrombin to thrombin 		EC 3.4.99.27   *Endopeptidases Enzyme Activation Viper Venoms
Pharma Action Fibrinolytic Agents 		J Biochem (Tokyo):83(2):559;1978; J Biol Chem 254(18):8751;1879; Thromb Res 15(1-2):143;1979; Thromb Res 15(1-2):27;1979; Thromb Res 7(4):611;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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