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Endopeptidases
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Definition
: A subclass of PEPTIDE HYDROLASES that catalyze the internal cleavage of PEPTIDES or PROTEINS.
Examples
Amyloid Precursor Protein Secretases
;
Aspartic Acid Endopeptidases
;
ATP-Dependent Endopeptidases
;
Brinolase
;
Coagulase
;
Cysteine Endopeptidases
;
Metalloendopeptidases
;
Serine Endopeptidases
;
Streptokinase
Other names
Peptide Peptidohydrolases
Substance
CAS Registry & name
Categories
Source
Drugs
*
USP46 protein, rat
EC 3.4.-
*Endopeptidases.
PLoS One. 2011;6(10):e26297.
USP46 protein, mouse
EC 3.4.-
*Endopeptidases.
Nat Genet. 2009 Jun;41(6):688-95.
AlpB endopeptidase, Lysobacter
EC 3.4.-
*Bacterial Outer Membrane Proteins
*Endopeptidases.
Dokl Biochem Biophys. 2011 Nov-Dec;441():298-301
Rpn11 protein, Drosophila
EC 3.4.-
*Endopeptidases
*Drosophila Proteins.
Exp Gerontol. 2012 Feb;47(2):170-8
TRABID protein, human
EC 3.4.-
*Endopeptidases.
Biochem J. 2001 Aug 1;357(Pt 3):617-23.
SENP-
1 protein, rat
EC 3.4.-
*Endopeptidases.
J Cereb Blood Flow Metab. 2012 Jan;32(1):17-22
MYSM1 protein, mouse
EC 3.4.99.-
*Endopeptidases.
Immunity. 2011 Dec 23;35(6):883-96
inner mitochondrial membrane peptidase 2-
like protein, mouse
EC 3.4.-
*Endopeptidases
*Mitochondrial Proteins
Membrane Proteins.
Aging Cell. 2011 Aug;10(4):584-94.
katanin-
like 1 protein, human
EC 3.4.-
*Endopeptidases.
Cell Cycle 2010 Jun 15;9(12):2403-11
ubiquitin-
specific peptidase 46, human
EC 3.4.-
*Endopeptidases.
J Hum Genet 2010 Mar;55(3):133-6
USP13 protein, human
EC 3.4.-
*Endopeptidases.
J Biol Chem 2011 Aug 5;286(31):27333-41
UBP13 protein, Arabidopsis
EC 3.4.99.-
*Endopeptidases
*Arabidopsis Proteins.
New Phytol 2011 Jul;191(1):92-106
UBP12 protein, Arabidopsis
EC 3.4.99.-
*Endopeptidases
*Arabidopsis Proteins.
New Phytol 2011 Jul;191(1):92-106
Ubp15 protein, S cerevisiae
EC 3.4.99.-
*Endopeptidases
*Saccharomyces cerevisiae Proteins.
Biochemistry 2011 Jul 26;50(29):6423-32
deubiquitinase USP37, human
EC 3.4.99.-
*Endopeptidases.
Mol Cell. 2011 May 20;42(4):511-23
USP19 protein, human
EC 3.4.-
*Endopeptidases.
EMBO Rep 2009 Jul;10(7):755-61
ovarian tumor domain-
containing 6B protein, human
EC 3.4.-
*Endopeptidases.
PLoS One 2011;6(1):e14514
Cops6 protein, zebrafish
EC 3.4.-
*Endopeptidases
*Zebrafish Proteins.
Int J Dev Biol 2011;55(1):19-24
USP46 protein, Xenopus
EC 3.4.-
*Endopeptidases
*Xenopus Proteins.
J Biol Chem 2011 Mar 4;286(9):7190-201
USP12 protein, Xenopus
EC 3.4.-
*Endopeptidases
*Xenopus Proteins.
J Biol Chem 2011 Mar 4;286(9):7190-201
ATXN3L protein, human
EC 3.4.19.12
*Endopeptidases.
J Biol Chem 2011 Feb 11;286(6):4555-65
Usp39 protein, zebrafish
EC 3.4.-
*Endopeptidases
*Zebrafish Proteins.
PLoS Genet 2011;7(1):e1001271
USP6 protein, mouse
EC 3.4.-
*Endopeptidases.
J Biol Chem 2010 Nov 19;285(47):37111-20
purpurase protein, Cryptelytrops purpureomaculatus
EC 3.4.-
*Crotalid Venoms
*Endopeptidases.
Comp Biochem Physiol C Toxicol Pharmacol 2010 Jan;151(1):131-6
L-
alanoyl-
D-
glutamate peptidase, bacteriophage T5
EC 3.4.99.-
*Endopeptidases
*Viral Proteins.
FEBS J. 2009 Dec;276(24):7329-42
BA1952 protein, Bacillus anthracis
EC 3.4.-
*Bacterial Proteins
*Endopeptidases.
Appl Environ Microbiol. 2009 Oct;75(19):6157-67
Usp8 protein, mouse
0
*Endopeptidases
*Ubiquitin Thiolesterase
*Endosomal Sorting Complexes Required for Transport.
USP8 protein, human
0
*Endopeptidases
*Ubiquitin Thiolesterase
*Endosomal Sorting Complexes Required for Transport.
Trends Biochem Sci. 2007 Dec;32(12):561-73
ubiquitin specific protease 36, Drosophila
EC 3.4.99.-
*Endopeptidases
*Drosophila Proteins.
Science 2009 Jan 9;323(5911):248-51
SENP7 protein, human
EC 3.4.22.-
*Endopeptidases.
J Biol Chem 2008 Nov 14;283(46):32045-55
Usp30 protein, human
EC 3.1.2.15
*Thiolester Hydrolases
*Mitochondrial Proteins
Endopeptidases.
Mol Biol Cell 2008 May;19(5):1903-11
taspase1, Drosophila
EC 3.4.22.-
*Drosophila Proteins
*Endopeptidases.
Mol Cell Biol 2007 Oct;27(20):7063-72
yjgB protein, Lactococcus lactis
EC 3.4.99.-
*Endopeptidases.
Appl Environ Microbiol 2007 Sep;73(18):5825-31
deubiquitinating enzyme A, human
EC 3.4.-
*Endopeptidases.
Science 2007 Dec 7;318(5856):1628-32
MV-
L lysin, bacteriophage phiMR11
EC 3.4.99.-
*Endopeptidases.
J Infect Dis 2007 Oct 15;196(8):1237-47
USP-
33 protein, rat
EC 3.4.-
*Endopeptidases.
Endocrinology 2007 Oct;148(10):4865-74
Pros26 protein, Drosophila
EC 3.4.-
*Endopeptidases
*Drosophila Proteins.
Genetics 2006 Jul;173(3):1377-87
Prosbeta2 protein, Drosophila
EC 3.4.-
*Endopeptidases
*Drosophila Proteins.
Genetics 2006 Jul;173(3):1377-87
Pros25 protein, Drosophila
EC 3.4.-
*Endopeptidases
Protein Subunits.
Biochim Biophys Acta 1993 Aug 19;1174(2):215-7
taspase1, mouse
EC 3.4.22.-
*Endopeptidases.
Genes Dev 2006 Sep 1;20(17):2397-409
AESP protein, Arabidopsis
EC 3.4.22.49
*Endopeptidases
*Cell Cycle Proteins.
Plant Cell 2006 May;18(5):1213-25
xFAM protein, Xenopus
EC 3.4.99.-
*Endopeptidases
*Xenopus Proteins
Ubiquitins.
Science. 2005 Dec 2;310(5753):1499-504
N(pro) protein, swine fever virus
EC 3.4.-
*Endopeptidases
*Viral Proteins.
Virology 2005 Sep 30;340(2):265-76
Usp7 protein, rat
EC 3.4.99.-
*Endopeptidases.
FEBS Lett 2005 Aug 29;579(21):4867-72
Bre5 protein, S cerevisiae
EC 3.4.99.-
*Endopeptidases
*Saccharomyces cerevisiae Proteins.
J Biol Chem 2005 Aug 12;280(32):29176-85
UBP8 protein, S cerevisiae
EC 3.4.99.-
*Endopeptidases.
Mol Cell Biol 2005 Jul;25(14):6123-39
Senp1 protein, mouse
EC 3.4.-
*Endopeptidases.
Mol Cell Biol 2005 Jun;25(12):5171-82
RN-
tre protein, Drosophila
EC 3.4.99.-
*Endopeptidases
*Drosophila Proteins.
Aph1C protein, mouse
EC 3.4.99.-
*Endopeptidases.
Proc Natl Acad Sci U S A 2005 Feb 1;102(5):1719-24
Aph1b protein, mouse
EC 3.4.99.-
*Endopeptidases.
Proc Natl Acad Sci U S A 2005 Feb 1;102(5):1719-24
Aph1a protein, mouse
EC 3.4.99.-
*Endopeptidases.
Proc Natl Acad Sci U S A 2005 Feb 1;102(5):1719-24
lonofibrase
EC 3.4.-
*Endopeptidases.
Thromb Res 2004;113(2):147-54
myulchikinase
EC 3.4.99.-
*Endopeptidases.
Biotechnol Lett 2004 Mar;26(5):393-7
UBP14 protein, Arabidopsis
0
*Endopeptidases
*Arabidopsis Proteins.
RCE1 protein, human
EC 3.4.22
*Endopeptidases
Lipoproteins
Protein Processing, Post-Translational.
Rce1 protein, mouse
EC 3.4.22
*Endopeptidases
Protein Processing, Post-Translational.
AtUBP3 protein, Arabidopsis
EC 3.4.-
*Endopeptidases
*Arabidopsis Proteins.
trypanolysin protein, Schistocerca gregaria
EC 3.4.-
*Endopeptidases
*Insect Proteins
*Lectins.
East Afr Med J 2003 Nov;80(11):575-80
SENP1b protein, Xenopus
EC 3.4.-
*Endopeptidases
*Xenopus Proteins.
Genes Cells 2004 Aug;9(8):723-36
SENP1a protein, Xenopus
EC 3.4.-
*Endopeptidases
*Xenopus Proteins.
Genes Cells 2004 Aug;9(8):723-36
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