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Lectins

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Definition: Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.     
Examples Antigens, CD22; Lectins, C-Type; Calnexin; Calreticulin; Galectins; Mannose-Binding Lectins; Plant Lectins; Receptors, N-Acetylglucosamine; Selectins 		Other names Isolectin; Lectins, Animal; Isolectins; Animal Lectins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NNTL lectin, Nymphaea  0   *Glycoproteins *Lectins Plant Proteins. Biosci Rep. 2011 Dec;31(6):465-75
EULS3 protein, Arabidopsis  0   *Arabidopsis Proteins *Lectins. Biochem Biophys Res Commun. 2011 Oct 14;414(1):101-5
OS9 protein, mouse  0   *Neoplasm Proteins *Lectins. Mol Med Report. 2011 Jul-Aug;4(4):687-92
galatrox protein, Bothrops atrox  0   *Viper Venoms *Lectins. Acta Biochim Biophys Sin (Shanghai) 2011 Mar;43(3):181-92
malectin protein, human  0   *Membrane Proteins *Lectins. Methods Enzymol. 2010;478():265-86
karatoxin, Hypodytes rubripinnis  0   *Glycoproteins *Lectins. J Pharmacol Sci. 2010;113(4):414-7
paracoccin, Paracoccidioides brasiliensis  0   *Fungal Proteins *Lectins. Yeast. 2010 Feb;27(2):67-76
beta-glucosidase aggregating factor  0   *Lectins. Phytochemistry. 2009 Jul-Aug;70(11-12):1355-65
c21orf63 protein, human  0   *Membrane Proteins *Lectins. J Biochem 2009 Sep;146(3):369-73
PAUF protein, human  0   *Lectins. Cancer Sci 2009 May;100(5):828-36
LecB protein, Pseudomonas aeruginosa  0   *Lectins. Chem Biol 2008 Dec 22;15(12):1249-57
malectin protein, Xenopus  0   *Membrane Proteins *Lectins. Mol Biol Cell 2008 Aug;19(8):3404-14
XTP3-B protein, human  0   *Lectins. J Biol Chem 2008 Jul 25;283(30):20914-24
odorranalectin, Odorrana grahami  0   *Lectins. PLoS ONE 2008;3(6) (dup#5):e2381
disaccharide receptor  0   *Lectins. Science 2007 Oct 26;318(5850):619-22
stenodactylin protein, Adenia stenodactyla  EC 3.2.2.-   *N-Glycosyl Hydrolases *Lectins. Neurotoxicology 2007 May;28(3):637-44
lanceolin protein, Adenia lanceolata  EC 3.2.2.-   *N-Glycosyl Hydrolases *Lectins. Neurotoxicology 2007 May;28(3):637-44
Siglecg protein, mouse  0   *Receptors, Antigen, B-Cell *Lectins. Nat Immunol 2007 Jul;8(7):695-704
lectin 60 kDa, Chinese mistletoe  0   *Plant Proteins *Lectins. Acta Biochim Biophys Sin (Shanghai) 2007 Jun;39(6):445-52
ZG16 protein, human  0   *Lectins. Biochem Biophys Res Commun 2007 Apr 13;355(3):679-86
SIGLEC14 protein, human  0   *Receptors, Cell Surface *Lectins. FASEB J 2006 Oct;20(12):1964-73
Pldn protein, mouse  0   *Carrier Proteins *Lectins.
erlectin protein, Xenopus  0   *Lectins. J Biol Chem 2006 May 5;281(18):12986-93
Siglech protein, mouse  0   *Receptors, Cell Surface *Lectins. BMC Genomics 2005 Nov 9;6:157
HSPC159 protein, human  0   *Lectins. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 May 1;62(Pt 5):474-6
XEEL protein, Xenopus  0   *Lectins. Glycobiology 2005 Mar;15(3):281-90
OPL I lectin  0   *Lectins.
lobster agglutinin 1  0   *Lectins.
carcinoscorpin  0   *Lectins.
X-epilectin, Xenopus  0   *Xenopus Proteins *Lectins Fucose. Int J Dev Biol 2004 Dec;48(10):1119-29
griffithsin protein, Griffithsia  0   *Algal Proteins *Lectins. J Biol Chem 2005 Mar 11;280(10):9345-53
IB4-saporin conjugate  0   *Lectins *Ribosome Inactivating Proteins, Type 1 Cytotoxins. Brain Res. 2004 Dec 10;1029(1):65-76Brain Res. 2004 Dec 10;1029(1)
wu:fb99b07 protein, zebrafish  0   *Proteoglycans *Zebrafish Proteins Lectins. Mech Dev 2004 Mar;121(3):301-12
trypanolysin protein, Schistocerca gregaria  EC 3.4.-   *Endopeptidases *Insect Proteins *Lectins. East Afr Med J 2003 Nov;80(11):575-80
LecRK protein, cotton  EC 2.7.1.-   *Protein-Serine-Threonine Kinases Lectins. DNA Seq 2004 Feb;15(1):58-65
isolectin B4-binding glycoprotein, rat  0   *Glycoproteins *Lectins. Life Sci. 2004 Apr 9;74(21):2627-42
ITLN2 protein, human  0   *Lectins.
agglutinin-B  0   *Lectins. Toxicon. 2003 Oct;42(5):525-32
agglutinin-A  0   *Lectins. Toxicon. 2003 Oct;42(5):525-32
LMAN2L protein, human  0   *Membrane Transport Proteins *Lectins. Exp Cell Res 2003 Aug 1;288(1):70-83
hemolectin protein, Drosophila  0   *Drosophila Proteins *Lectins. Biochem J. 2001 Oct 1;359(Pt 1):99-10835-45
scytovirin protein, S varium  0   *Bacterial Proteins *Carrier Proteins *Lectins Cyanobacteria. Biochemistry 2003 Mar 11;42(9):2578-84
EspecL  0   *Lectins. Arch Biochem Biophys 2003 Feb 15;410(2):222-9
Hag-1 protein, Moraxella catarrhalis  0   *Bacterial Proteins Antigens, Bacterial Hemagglutinins Lectins. Infect Immun 2002 Aug;70(8):4523-33
SIGLEC11 protein, human  0   *Membrane Proteins *Lectins. J Biol Chem 2002 Jul 5;277(27):24466-74
Jacob protein, Entamoeba histolytica  0   *Protozoan Proteins *Lectins. Infect Immun 2002 Jun;70(6):3259-63
leczyme protein, Rana  EC 3.1.-   *Ribonucleases *Amphibian Proteins *Lectins. Methods Enzymol 2001;341:368-74
influenza virus-hemagglutinin peptide 2 (1-48)  0   *Peptide Fragments *Viral Proteins Lectins Hemagglutinins. Arch Biochem Biophys 2001 Dec 1;396(1):89-98
rhamnose-binding lectin, trout  0   *Lectins *Fish Proteins. Biosci Biotechnol Biochem 2001 Jun;65(6):1328-38
lectin 36 kDa, Halocynthia roretzi  0   *Lectins. J Immunol 2001 Oct 15;167(8):4504-10
Igl2 protein, Entamoeba histolytica  0   *Protozoan Proteins *Lectins. Infect Immun 2001 Sep;69(9):5892-8
Igl1 protein, Entamoeba histolytica  0   *Protozoan Proteins *Lectins. Infect Immun 2001 Sep;69(9):5892-8
SIGLEC12 protein, human  0   *Membrane Proteins *Lectins. J Biol Chem 2001 Jun 29;276(26):23816-24
ITLN1 protein, human  0   *Cytokines *Lectins GPI-Linked Proteins. J Biol Chem 2001 Jun 29;276(26):23456-63
FREP4 protein, Biomphalaria glabrata  0   *Immunoglobulins *Lectins Snails. Gene 2001 May 16;269(1-2):155-65
FREP2 protein, Biomphalaria glabrata  0   *Immunoglobulins *Lectins. Gene 2001 May 16;269(1-2):155-65
Chi3l3 protein, mouse  EC 3.2.1.52   *beta-N-Acetylhexosaminidases *Lectins. J Biol Chem 2001 May 18;276(20):17497-506
SIGLEC10 protein, human  0   *Receptors, Cell Surface *Lectins. Biochem J 2001 Apr 15;355(Pt 2):489-97
Tachypleus plasma lectin-2  0   *Lectins Hemolymph. J Biol Chem 2001 Mar 30;276(13):9631-9
Tachypleus plasma lectin-1  0   *Lectins Hemolymph Horseshoe Crabs. J Biol Chem 2001 Mar 30;276(13):9631-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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