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Streptokinase

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Definition: Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.  an enzyme; see note on STREPTODORNASE AND STREPTOKINASE   
Pharmacological Action Fibrinolytic Agents
See Also Streptodornase and Streptokinase
Examples Anistreplase; Streptodornase and Streptokinase 		Other names Streptodecase; Streptase; Kabivitrum; Kabikinase; Distreptase; Celiase; Awelysin; AvelizinDrugs* : STREPTASE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CCG-2979  0   *Quinazolines Streptokinase/antagonists & inhibitors. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3469-74.
actinokinase  EC 3.4.-21.-   *Streptokinase Escherichia coli. Indian J Exp Biol 2001 May;39(5):410-5
streptokinase-B-chain plasmin complex  0   *Fibrinolysin *Streptokinase Drug Combinations. Thromb Haemost 1986;56(1):71
streptokinase-plasminogen complex  0   *Plasminogen *Streptokinase Drug Combinations. Behring Inst Mitt 1986;(79):263
streptokinase-N-vinylpyrrolidone copolymer  0   *Streptokinase Povidone/*analogs & derivatives. Biokhimiia 1985;50(8):1312
BRL 33575  94587-92-5 BRL 33575  *Plasminogen *Streptokinase. Thromb Haemost 1984;51(3):403
streptozyme test  0   *Serologic Tests Erythrocytes Streptokinase Streptolysins. Clin Pediatr 12(6):341;1973; J Pediatr 1980;96(3):367

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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