Definition: C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
includes cardadienolides & cardatrienolides; do not confuse with CARDANOLIDES
digoxin-like factors [ digitalis-like factors,digoxin-immunoreactive factors,digoxin-like immunoreactive factor,digoxin-like immunoreactive substance,endalin,endogenous digitalis-like factor,endogenous digoxin-like factor,endoxin,ouabain-like factor,ouabain-like natriuretic factor ] cardenolide factors found in plasma which shares immunological determinants with digoxin and ouabain; high levels of endoxin correlated with hypertension
