encyclopedia of medical concepts
ψ 
ψ 
ψ 

Ouabain

More information in Books or onNLM PubMed
Definition: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.     
Pharmacological Action Cardiotonic Agents; Enzyme Inhibitors 		Other names G-Strophanthin; Acocantherin; K, Acolongifloroside; G Strophanthin; Acolongifloroside K
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tyrosyl-ouabain, radioiodinated  0   Ouabain/*analogs & derivatives Tyrosine/*analogs & derivatives. Clin Chem. 2001 Jan;47(1):95-101
endobain E  0   Ouabain/*analogs & derivatives Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors. Neuroscience 1999 May;90(2):573-9
seminaphthofluoresceinyl ethylenediamine-ouabain  0   *Fluoresceins Ouabain/*analogs & derivatives. Eur J Biochem 1997 Oct 1;249(1):301-8
rhodol green-ethylenediamine-ouabain  0   *Fluoresceins Ouabain/*analogs & derivatives. Eur J Biochem 1997 Oct 1;249(1):301-8
fluoresceinyl ethylenediamine-ouabain  0   *Fluoresceins Ouabain/*analogs & derivatives. Eur J Biochem 1997 Oct 1;249(1):301-8
sodium-potassium ATPase inhibitory factor  0   *Ouabain Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Proc Natl Acad Sci U S A 1993 Sep 1;90(17):8189-93
ouabain-sepharose  0   Ouabain/*analogs & derivatives Sepharose/*analogs & derivatives. Biochim Biophys Acta 1987;899(2):247
4-aminobenzenediazonium ouabain  83859-88-5   *Diazonium Compounds Ouabain/*analogs & derivatives. Biochemistry 1983;22(20):4685
digoxin-like factors  0   *Cardenolides *Saponins Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors Ouabain.
Pharma Action Enzyme Inhibitors 		Hypertension 1982;4(3):348
NAP-ouabain  68613-44-5 Card-20(22)-enolide, 3-((4-(2-((4-azido-1-nitrophenyl)amino)ethyl)hexahydro-6-hydroxy-7-methyl-1,4-oxazepin-2-yl)oxy)-5,11,14,19-tetrahydroxy-, (3beta(2R,6R,7S),5beta,11alpha)  *Azides Ouabain/*analogs & derivatives. J Biochem 1982;91(1):97
cardiac glycoside receptors  0   *Sodium-Potassium-Exchanging ATPase Cardiac Glycosides Digoxin Ouabain. Biochem Pharmacol 1980;29(24):3219
4-nitrophenyltriazene ouabain  0   *Triazenes Ouabain/*analogs & derivatives. J Biol Chem 1980;255(20):9936
2-nitro-5-azidobenzoylouabain  0   Ouabain/*analogs & derivatives. Biochemistry 17(17):3667;1978
anthroylouabain  62026-02-2 Card-20(22)-enolide, 3-((3-O-(9-anthracenylcarbonyl)-6-deoxy-alpha-L-mannopyranosyl)oxy)-1,5,11,14,19-pentahydroxy-, (1beta,3beta,5beta,11alpha)  *Anthracenes Ouabain/*analogs & derivatives. Biochemistry 16(3):531;1977; Biochemistry 1980;19(5):969; J Biol Chem 1980;255(2):459
ouabagenin  508-52-1   Ouabain/*analogs & derivatives. Arch Int Pharm 232(2):339;1978
dihydroouabain  1183-35-3   Ouabain/*analogs & derivatives. Arch Int Pharmacodyn Ther (2):339;1978; Circ Res 37(5):674;1975; J Pharmacol Exp Ther 199(1):255;1976; Pfluegers Arch 358(3):225;1975

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy