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Fluoresceins

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Definition: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.     
Pharmacological Action Fluorescent Dyes
Examples Eosine I Bluish; Eosine Yellowish-(YS); Erythrosine; Fluorescein; Fluorescein-5-isothiocyanate; Rose Bengal 		Other names Tetraiodofluorescein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
UK101-Fluor  0   *Dipeptides *Fluoresceins. Bioorg Med Chem. 2012 Jan 15;20(2):607-13.
Flu-1 compound  0   *Fluoresceins *Oximes Fluorescent Dyes. Chem Commun (Camb). 2011 Nov 21;47(43):11978-80.
O,O'-di-(3-(2-carboxy-8-oxo-7-(2-thiophen-2-yl-acetylamino)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)allyl)-2',7'-dichlorofluorescein  0   *Fluoresceins *Azabicyclo Compounds Fluorescent Dyes. Anal Biochem. 2011 Dec 1;419(1):9-16.
O,O'-di-(2-oxoethyl)-2',7'-dichlorofluorescein  0   *Fluoresceins Fluorescent Dyes. Anal Biochem. 2011 Dec 1;419(1):9-16.
4',5'-fluorescein dicarboxaldehyde  0   *Fluoresceins. PLoS One. 2011;6(7):e21387.
2-diethanolamino-4,8-diheptamethyleneimino-6-((N-6-(fluorescein-6-carboxamido)hexanoylaminoethyl)ethanolamino)pyrimido(5,4-d)pyrimidine  0   *Fluoresceins *Pyrimidines. Bioconjug Chem 2011 Jun 15;22(6):1221-7
5-benzoylcarbonylfluorescein  0   *Fluoresceins. J Am Chem Soc. 2011 Jul 13;133(27):10629-37
dibenzylfluorescein  0   *Fluoresceins. Biochem Pharmacol 2008 Mar 1;75(5):1161-9
F-NP41 peptide  0   *Fluoresceins *Peptides. Laryngoscope 2011 Apr;121(4):805-10
FAMX-CTT-54  0   *Fluoresceins *Organophosphorus Compounds Fluorescent Dyes. Prostate 2011 Jan 1;71(1):52-61
2,4,5,7-tetrabromo-4,5,6,7-tetrachlorofluorescein  0   *Fluoresceins. J Hazard Mater 2008 Mar 21;152(1):216-20
E339-3D6 compound  0   *Dipeptides *Fluoresceins. FASEB J 2010 May;24(5):1506-17
trihydroxytrioxatriangulene  0   *Fluoresceins. Chemistry. 2010 Mar 8;16(10):2992-6
p-methoxycarbonylphenyl fluorone  0   *Fluoresceins. Chem Pharm Bull (Tokyo). 2009 Dec;57(12):1405-8
fluorescein hydrizido 2-imidophenylboronic ester  0   *Fluoresceins. Dalton Trans. 2010 Jan 14;(2):568-76
fluorescein hydrizido 2-imidophenol  0   *Fluoresceins. Dalton Trans. 2010 Jan 14;(2):568-76
2-bromophenylfluorone  0   *Fluoresceins. Anal Sci 2009 Dec;25(12):1457-60
poly(NIPAAm-co-FL)  0   *Acrylic Resins *Fluoresceins. Anal Sci. 2009 Aug;25(8):1043-7
hydroxyphenyl fluoroscein  0   *Fluoresceins. Hypertens Res 2008 Jan;31(1):141-51
bis(p-methylbenzenesulfonyl)dichlorofluorescein  0   *Fluoresceins. Electrophoresis. 2009 Jun;30(11):1983-90
carboxyfluorescein-D-Ala-D-Ala-D-Ala  0   *Oligopeptides Fluoresceins. Anal Chem. 2009 Jun 15;81(12):5095-8
5-carboxyfluorescin-alanyl-alanyl-alanine  0   *Fluoresceins *Oligopeptides. Electrophoresis 2009 Apr;30(7):1194-7
2',4',5',7'-tetrachloro-6-(5-carboxypentyl)-4,7-dichloro fluorescein succinimidyl ester  0   *Fluoresceins *Succinimides. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2957-9
tryptophyl-(fluoresceinyl-lysyl)-tyrosyl-methionyl-valyl-methioninamide  0   *Fluoresceins *Oligopeptides. Cytometry A 2009 Mar;75(3):264-70
fluoro-jade C  0   *Fluoresceins. Brain Res 2008 Nov 19;1241:157-67
N-fluoresceinyl-3,7,12-trihydroxycholan-24-amide  0   *Cholic Acids *Fluoresceins. Photochem Photobiol Sci 2008 Jul;7(7):860-6
B 10380  0   *Fluoresceins Bradykinin/*analogs & derivatives. Peptides 2008 Sep;29(9):1626-30
6-oxy-(acetylethylenediamine)fluorescein  0   *Fluoresceins. J Sep Sci 2008 Apr;31(6-7):999-1006
1,2,7,8-dibenzofluorescein  0   *Fluoresceins. Photochem Photobiol Sci 2008 Mar;7(3):299-302
4,7,4',5'-tetra-chloro-6-(5-carboxypentyl)fluorescein  0   *Fluoresceins. Bioorg Med Chem Lett 2008 Mar 15;18(6):1977-9
4,7,2',7'-tetrachloro-6-(5-carboxypentyl)fluorescein  0   *Fluoresceins. Bioorg Med Chem Lett 2008 Mar 15;18(6):1977-9
3-amino-4-monomethylamino-2',7'-difluorofluorecein  0   *Ethylamines *Fluoresceins. Free Radic Res. 2007 Nov;41(11):1289-300
2-phenylamino-3-methyl-6-di-n-butylaminofluoran  0   *Fluoresceins *Aniline Compounds. J Environ Sci (China) 2007;19(10):1178-82
4'-aminomethyl-fluorescein  0   *Fluoresceins. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1467-70
4',5'-bis-aminomethyl-fluorescein  0   *Fluoresceins. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1467-70
myristoyl-beta-alanyl-(arginyl)7-lysyl(flurosceine isothiocyanate)amide  0   *Fluoresceins *Oligopeptides. Chembiochem 2004 Aug 6;5(8):1148-51
6-oxy-(acetyl piperazine) fluorescein  0   *Fluoresceins *Piperazines. J Chromatogr A. 2007 Oct 26;1169(1-2):77-85
4,5-dibromofluorescein  0   *Fluoresceins. Anal Chim Acta 2007 Sep 19;599(2):271-8
1-(4-(N-(1-carboxy-2-(3,6-dihydroxy-9H-xanthen-9-yl)phenyl-5-yl)aminobenzyl))ethylenediamine-N,N,N',N'-tetraacetic acid  0   *Fluoresceins Edetic Acid/*analogs & derivatives. Electrophoresis 2007 Jul;28(14):2448-57
synthetic transcription factor 1  0   *Fluoresceins *Pyrroles. Nucleic Acids Symp Ser (Oxf) 2006;(50):29-30
leadfluor-1  0   *Fluoresceins. J Am Chem Soc 2006 Jul 26;128(29):9316-7
(4-sulfamoylphenylethyl)thioureido fluorescein  0   *Fluoresceins Thiourea/*analogs & derivatives. J Am Chem Soc 2006 Jun 28;128(25):8329-35
Zn(II)-DpaTyr  0   *Fluoresceins *Organometallic Compounds Zinc. Chem Commun (Camb) 2006 Oct 14;(38):4024-6
TokyoGreen-NPE AM  0   *Fluoresceins. J Am Chem Soc 2007 May 30;129(21):6696-7
2-(6-(4'-hydroxy)phenoxy-3H-xanthen-3-on-9-yl)benzoic acid  0   *Fluoresceins. Mitochondrion 2007 Feb-Apr;7(1-2):106-18
3',6'-bis(diphenylphosphinyl)fluorescein  0   *Fluoresceins. Chemistry 2007;13(5):1411-6
6-carboxy-2',4,4',5',7,7'-hexachlorofluorescein  0   *Fluoresceins. Electrophoresis 2007 Mar;28(5):837-42
4',5'-bis((bis(carboxymethyl)amino)methyl)fluorescein  0   *Fluoresceins. J Chromatogr A 2007 Jan 26;1140(1-2):230-5
fluoro-emerald  0   *Dextrans *Fluoresceins. J Neurosci Methods. 2006 Jul 15;155(1):20-7
DT-2 compound  0   *Fluoresceins *Peptide Fragments. Front Biosci 2005;10:1302-12
7-chlorofluorescein  0   *Fluoresceins. J Fluoresc 2005 Nov;15(6):829-33
4-chlorofluorescein  0   *Fluoresceins. J Fluoresc 2005 Nov;15(6):829-33
aminophenyl fluorescein  0   *Aniline Compounds *Fluoresceins. J Pineal Res 2006 Jan;40(1):10-7
5-(4,6-dichloro-s-triazin-2-ylamino) fluorescein  0   *Fluoresceins *Triazines. J Chromatogr A. 2006 Jan 13;1102(1-2):273-9
4-fluoresceinthiocarbamoyl-6-aminocaproyl-prolyl-2-(hydroxyacetyl)pyrrolidine  0   *Dipeptides *Fluoresceins. J Med Chem 2005 Nov 17;48(23):7093-5
o-sulfophenylfluorone  0   *Fluoresceins. Anal Sci. 2005 Oct;21(10):1237-40
N-(fluorescein-5-thiocarbamoyl)-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine, triethylammonium salt  0   *Fluoresceins *Phosphatidylethanolamines. Anal Biochem. 2005 Sep 1;344(1):102-7
5-carboxyfluorescein diacetate acetoxymethyl ester  0   *Fluoresceins. Anal Biochem. 2005 Sep 1;344(1):76-85
5-((4,6-dichlorotriazin-2-yl)amino)fluorescein hydrochloride-Celite complex-labeled Saccharomyces cerevisiae beta-glucan  0   *Fluoresceins *beta-Glucans. Infect Immun 2005 Oct;73(10):6340-9
1-(3-(fluoresceinylthioureidoalanyl-alanyl-alanyl-L-leucyl-glycyl-L-norvalyl-L-prolylamino)propylamino)anthracene-9,10-dione  0   *Fluoresceins *Oligopeptides. Leukemia 2005 Sep;19(9):1628-33
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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