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Edetic Acid

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Definition: A chelating agent (CHELATING AGENTS) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.     
Pharmacological Action Anticoagulants; Chelating Agents; Food Additives 		Other names Tetracemate; Ethylenediaminetetraacetic Acid; Edetates; Edathamil; EDTA; Tetacine, Calcium; Ethylene Dinitrilotetraacetate, Disodium; Edetate, Calcium Disodium; EDTA, Stannous; EDTA, Potassium; EDTA, Magnesium Disodium; EDTA, Gallium; EDTA, Distannous; EDTA, Disodium; EDTA, Dicobalt; EDTA, Copper; EDTA, Chromium; Dinitrilotetraacetate, Ethylene; Dinitrilotetraacetate, Disodium Ethylene; Acid, EthylenedinitrilotetraaceticDrugs* : CALCIUM DISODIUM VERSENATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5,10,15-tris(N-methylpyridinium-4-yl)-20-(1-phenyl-2-(ethylene diamine-tetraacetic acid))-21H,23H-porphyrin  0   *Porphyrins Edetic Acid/*analogs & derivatives. Bioorg Chem. 2012 Feb;40(1):108-13.
Sideroxyl  0   Edetic Acid/*analogs & derivatives. Free Radic Biol Med. 2010 Dec 1;49(11):1629-37
N,N'-bis(2-hydroxy-5-methylphenyl)ethylendiamine-N,N'-diacetic acid  0   Edetic Acid/*analogs & derivatives. J Agric Food Chem 2009 Sep 23;57(18):8504-13
((EDTAH)Fe(O2)Fe(EDTAH))2  0   *Ferrous Compounds Edetic Acid/*analogs & derivatives. J Phys Chem A. 2009 Oct 29;113(43):11926-37
deoxythymidine-EDTA  0   Edetic Acid/*analogs & derivatives Thymidine/*analogs & derivatives. Biophys Chem 2007 Sep;129(2-3):148-62
1-(4-(N-(1-carboxy-2-(3,6-dihydroxy-9H-xanthen-9-yl)phenyl-5-yl)aminobenzyl))ethylenediamine-N,N,N',N'-tetraacetic acid  0   *Fluoresceins Edetic Acid/*analogs & derivatives. Electrophoresis 2007 Jul;28(14):2448-57
Smear Clear  0   *Edetic Acid. J Endod 2007 Apr;33(4):472-5
Ph-TTHA  0   Edetic Acid/*analogs & derivatives. Org Biomol Chem. 2005 Feb 7;3(3):454-61
ethylenodiamino-N,N'-bis(acetocarboxyl)-N,N'-bis(acetyl(1-(3'-aminopropyl)-3-hydroxy-2-methyl-4-pyridinone))  0   Edetic Acid/*analogs & derivatives. J Inorg Biochem 2005 Sep;99(9):1845-52
N-hexadecyl ethylenediamine triacetic acid  0   Edetic Acid/*analogs & derivatives. J Colloid Interface Sci 2004 Nov 15;279(2):548-51
4-aminiosalicylic acid ethylenediaminetetraacetate terbium(III)  0   *Organometallic Compounds Edetic Acid/*analogs & derivatives Terbium. Anal Biochem 2005 Jan 1;336(1):64-74
5-aminosalicylic acid ethylenediaminetetraacetate europium(III)  0   *Organometallic Compounds Edetic Acid/*analogs & derivatives Europium. Anal Biochem 2005 Jan 1;336(1):64-74
EDTA-bis(L-tryptophan methyl ester)  0   Edetic Acid/*analogs & derivatives Tryptophan/*analogs & derivatives. Chem Commun (Camb) 2003 Dec 7;(23):2884-5
Ultracid F  0   *Benzalkonium Compounds *Edetic Acid *Sodium Fluoride Dentin-Bonding Agents. Quintessence Int 2004 Jan;35(1):56-60
aqua(edetic acid)chromium(III)  0   *Edetic Acid *Organometallic Compounds Chromium. J Biomol Struct Dyn 2003 Feb;20(4):575-87
Alpron  0   *Edetic Acid *Sodium Hypochlorite Infection Control, Dental.
Pharma Action Disinfectants 		Br Dent J 2002 Nov 23;193(10):593-6; discussion 584
N,N'-bis(3,4,5-trimethoxybenzyl)ethylenediamine-N,N'-diacetic acid diacetoxymethyl ester  0   Edetic Acid/*analogs & derivatives. J Med Chem 2000 Apr 6;43(7):1418-21
1-(1,4,5-dimethoxy-2-nitrophenyl) ethylenediaminetetraacetic Acid  0   Edetic Acid/*analogs & derivatives. J Physiol 2002 Feb 1;538(Pt 3):707-16
ethylenediaminetetraacetic acid bis-(ethyl phenylalaninate)  0   Edetic Acid/*analogs & derivatives Chelating Agents. Bioorg Med Chem Lett 2001 Oct 8;11(19):2573-5
BQQ-EDTA conjugate  0   *Edetic Acid *Quinoxalines. Chem Biol 1999 Nov;6(11):771-7
NTB-cysteaminyl-EDTA  0   *Edetic Acid *Nitrobenzoates. Biochemistry 1999 Sep 14;38(37):11914-25
isothiocyanobenzyl ethylenediamine tetracetic acid  0   *Isothiocyanates Edetic Acid/*analogs & derivatives. Nucl Med Biol 1999 Feb;26(2):239-43
111-indium-ethylenediaminetetracetic acid-biotin  0   Biotin/*analogs & derivatives Edetic Acid/*analogs & derivatives Contrast Media Indium Radioisotopes. J Nucl Med 1999 Mar;40(3):484-90
CGP 75254A  0   Edetic Acid/*analogs & derivatives. J Pharm Sci 1998 Sep;87(9):1041-5
chitosan-EDTA  0   *Chitosan Edetic Acid/*analogs & derivatives Gels. J Pharm Pharmacol 1998 May;50(5):445-52
propylene-1,2-diaminotetraacetic acid-ruthenium(III) complex  0   *Organometallic Compounds Edetic Acid/*analogs & derivatives Ruthenium. Biochem J 1997 Dec 1;328(Pt 2):559-64
(4-(N-alpha-fluorenylmethoxycarbonyl-aspartic acid beta-amido)benzyl)EDTA tetra tert-butyl ester  0   Aspartic Acid/*analogs & derivatives Edetic Acid/*analogs & derivatives. Bioconjug Chem 1997 Mar-Apr;8(2):249-52
OST7-(1-(4-(4-(2-maleimidoethoxy)succinamido)benzyl)ethylenediamine-N,N,N',N'-tetraacetic acid)  0   *Antibodies, Monoclonal *Immunoconjugates Edetic Acid/*analogs & derivatives Immunoconjugates. Nucl Med Biol 1996 Feb;23(2):129-36
isothiocyanatobenzyl-EDTA  0   *Isothiocyanates Edetic Acid/*analogs & derivatives. Bioconjug Chem 1996 May-Jun;7(3):283-9
MCP-4-EDTA-SH  0   *Peptides Edetic Acid/*analogs & derivatives. Bioconjug Chem 1995 Nov-Dec;6(6):683-90
S-(2-nitrophenylsulfenyl)cysteaminyl EDTA  0   Edetic Acid/*analogs & derivatives. Proc Natl Acad Sci U S A 1996 Feb 20;93(4):1370-5
ProSol PDX  0   *Edetic Acid *Polysorbates *Sodium Dodecyl Sulfate *Sodium Bicarbonate Drug Combinations Dental Scaling. Quintessence Int 1995 Dec;26(12):849-58
N,N'-bis(3,4,5-trimethoxybenzyl)ethylenediamine N,N'-diacetic acid  0   Edetic Acid/*analogs & derivatives. Biochem Pharmacol 1996 Jan 26;51(2):103-15
1-(4-(5-maleimidopentyl)aminobenzyl)ethylenediaminetetraacetic acid  155015-71-7   *Maleimides Edetic Acid/*analogs & derivatives. Nucl Med Biol 1995 Jul;22(5):555-64
Tubulicid Red Label  161445-62-1   *Edetic Acid. Oper Dent 1995 May-Jun;20(3):100-5
biotinyl-hydrazino-EDTA  0   Biotin/*analogs & derivatives Edetic Acid/*analogs & derivatives Indium Radioisotopes Organotechnetium Compounds. Nucl Med Commun 1995 Jan;16(1):38-46
Restore polishing paste  0   *Boric Acids *Edetic Acid *Glycerol Drug Combinations Dental Polishing. Angle Orthod 1995;65(2):103-10
N,N'-bis(dibenzyl)ethylenediaminediacetic acid  0   Edetic Acid/*analogs & derivatives. Free Radic Res 1995 Jan;22(1):67-86
manganese poly-N,N'-bis-2,2'-ethylenedioxydiethylenenitrilo-N-(,beta-dihydroxypropane)-carbonylmethylene-ethylenediamine-N,N'-diacetate  0   *Polyethylene Glycols Edetic Acid/*analogs & derivatives. Invest Radiol 1994 Jun;29 Suppl 2;S217-9
thioureabenzyl-EDTA  0   Edetic Acid/*analogs & derivatives. Nucl Med Commun 1994 Jun;15(6):483-91
EDTA-(2-aminoethyl 2-pyridyl disulfide)-Fe  0   Edetic Acid/*analogs & derivatives. Biochemistry 1993 Nov 30;32(47):12761-7
N-(iodoacetyl)-4-phenylenediamine-EDTA  0   *Phenylenediamines Edetic Acid/*analogs & derivatives. Bioconjug Chem 1993 May-Jun;4(3):219-25
bis(2,2'-6',2''-terpyridineplatinum(I))arginyl-EDTA  0   *Organoplatinum Compounds Edetic Acid/*analogs & derivatives. Nucleic Acids Res 1993 Apr 25;21(8):1983-90
4-nitrobenzyl-EDTA  0   Edetic Acid/*analogs & derivatives. Bioconjug Chem 1992 Sep-Oct;3(5):420-3
3,6-dimethylaminodibenzopyridonium edetate  143578-51-2 10H-Dibenz(b,e)iodinium, 3,7-bis(dimethylamino)-, salt with N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine) (1:1)  *Onium Compounds Edetic Acid/*analogs & derivatives. Yao Hsueh Hsueh Pao 1992;27(6):407-11
N,N'-bis(2-hydroxy-5-(ethylene-beta-carboxy)benzyl)ethylenediamine N,N'-diacetic acid  143557-99-7   Edetic Acid/*analogs & derivatives. J Nucl Med 1992 Jul;33(7):1366-72
EOTUBE  128817-30-1 Glycine, N,N'-(1-((4-((((2-hydroxyethyl)amino)thioxomethyl)amino)phenyl)methyl)-1,2-ethanediyl)bis(N-(carboxymethyl))  Edetic Acid/*analogs & derivatives Haptens. Cancer Res 1991;51(24):6650
N-(2-hydroxy-3,5-dimethylbenzyl)-N-(2-hydroxy-5-bromoacetamidobenzyl)ethylenediamine-N,N'-diacetic acid  126753-16-0   Edetic Acid/*analogs & derivatives. Int J Rad Appl Instrum (B) 1991;18(5):477
lac repressor (1-56), ((EDTA-Fe)-gamma-aminobutyryl)  0   *Edetic Acid *Repressor Proteins. Nucleic Acids Res 1991;19(19):5233
N-carboxymethyl)-N-(2-(bis(carboxymethyl)amino)ethyl)-3-(4-(N'-(2-((3,7,12-trihydroxycholan-24-oyl)amino)ethyl)(thioureido)phenyl)alanine  132910-41-9   *Cholic Acids Edetic Acid/*analogs & derivatives. Bioconjug Chem 1991;2(2):117
Tris-borate-EDTA buffer  0   *Boric Acids *Edetic Acid *Tromethamine Buffers. Biotechniques 991;10(2):182
benzyl-EDTA  106145-38-4   Edetic Acid/*analogs & derivatives. Bioconjug Chem 1990;1(4):278
N,N'-bis(2-hydoxybenzyl)-1-(4-bromoacetamidobenzyl)-1,2-ethylenediamine-N,N'-diacetic acid  126926-47-4   Edetic Acid/*analogs & derivatives. Bioconjug Chem 1990;1(3):204
iron(III) N,N'-bis(5-bromo-2-hydroxybenzyl)ethylenediamindiacetic acid  107539-31-1   *Ferric Compounds Edetic Acid/*analogs & derivatives. Magn Res Med 1991;17(1):164
iron(III) N,N'-bis((5-bromo-2-hydroxyphenyl)glycinate)  113530-42-0   *Ferric Compounds Edetic Acid/*analogs & derivatives. Magn Reson Med 1991;17(1):164
Fe-HBED  0   *Organometallic Compounds Edetic Acid/*analogs & derivatives Iron Magnetic Resonance Imaging. Invest Radiol 1990;25(Suppl 1):S58
indium 1-(4-isothiocyanatobenzyl)ethylenediaminetetraacetic acid  0   *Organometallic Compounds Edetic Acid/*analogs & derivatives Indium Indium Radioisotopes. J Nucl Med 1990;31(2):218
technetium Tc 99m ethylenediaminetetraacetohydroxamic acid  0   *Organotechnetium Compounds Edetic Acid/*analogs & derivatives. Int J Rad Appl Instrum (B) 1989;16(8):765
N,N'-bis(pyridoxal-5-phosphate)ethylenediamine-N,N'-diacetic acid  119797-12-5   Edetic Acid/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives Manganese.
Pharma Action Contrast Media 		Radiology 1989;172(1):59TESLASCAN
aminobenzyl-EDTA  84256-90-6   Edetic Acid/*analogs & derivatives. J Nucl Med 1988;29(11):1817
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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