encyclopedia of medical concepts
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Biotin

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Definition: A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.  /ther use: coordinate disease with /drug ther, not /diet ther; deficiency: coordinate BIOTIN /defic (IM) with VITAMIN B DEFICIENCY (IM)   
Pharmacological Action Vitamin B Complex
See Also Avidin; Biotinidase Deficiency; Holocarboxylase Synthetase Deficiency; Multiple Carboxylase Deficiency 		Other names Vitamin H; Roche, Biotine; Hermes, Biotin; H, Vitamin; Gelfert, Biotin; Biotinratiopharm; Biotin ratiopharm Brand; Biotin ratiopharm; Biotin Ziethen Brand; Biotin Strathmann Brand; Biotin Simons Brand; Biotin Roche Brand; Biotin Medopharm Brand; Biotin Hermes Brand; Biotin Dermapharm Brand; Biotin Biocur Brand; ratiopharm Brand of Biotin; medobiotin; e+b Pharma Brand of Biotin; Ziethen Brand of Biotin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CH5164840  0   *Benzoquinones *Lactams, Macrocyclic Biotin HSP90 Heat-Shock Proteins/antagonists & inhibitors. Cancer Sci. 2012 Feb;103(2):342-9
3-(iodobenzoyl)norbiotinamide-PTD-ODD-SAV fusion protein  0   *Recombinant Fusion Proteins Biotin/*analogs & derivatives Iodine Radioisotopes. Cancer Sci. 2011 Nov;102(11):2090-6.
(4,7-bis-carboxymethyl-10-(1-(2-(5-(2-oxohexahydrothieno(3,4-d)imidazol-6-yl)-pentanoylamino)ethyl)-1H-(1,2,3)triazol-4-ylmethyl)-1,4,7,10-tetraazacyclododec-1-yl)acetic acid  0   *Heterocyclic Compounds, 1-Ring Biotin/*analogs & derivatives Ligands. J Drug Target 2011 Jul;19(6):418-26
EP 224283  0   *Oligosaccharides Biotin/*analogs & derivatives Factor XI/antagonists & inhibitors Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors. J Pharmacol Exp Ther 2011 Aug;338(2):412-20
biotinyl-1(1-pyrene)methylamide  0   *Pyrenes Biotin/*analogs & derivatives. J Photochem Photobiol B 2011 Jun 2;103(3):251-5
cyanurbiotindipropionylsuccinimide  0   *Succinimides Biotin/*analogs & derivatives Cross-Linking Reagents. Mol Cell Proteomics 2011 Feb;10(2):M110.001420
DFK 1012  0   Acetylglucosamine/*analogs & derivatives Biotin/*analogs & derivatives. J Biol Chem 2011 Feb 18;286(7):5727-35
N-(6-(4-(5-(((5-chloro-3-methyl-1-benzothien-2-yl)sulfonyl)amino)-2-methoxyphenyl)piperazin-1-yl)hexyl)-5-(-2-oxohexahydro-1H-thieno(3,4-d)imidazol-4-yl)pentanamide  0   *Piperazines Biotin/*analogs & derivatives Ligands Receptors, Serotonin. J Med Chem 2010 Oct 14;53(19):7095-106
ACM-14 peptide  0   *Peptides Biotin/*analogs & derivatives. Anticancer Res 2010 Jun;30(6):1887-95
EP 217609  0   *Oligosaccharides Biotin/*analogs & derivatives. Thromb Haemost 2009 Nov;102(5):804-11
N-9-oxo-15-hydroxyprosta-10,13-dien-1-oyl-N-biotinoyl-1,6-diaminohexane  0   *Prostaglandins A Biotin/*analogs & derivatives. Chem Biol Interact 2010 Jan 5;183(1):212-21
idrabiotaparinux  0   *Oligosaccharides Biotin/*analogs & derivatives. Semin Thromb Hemost 2009 Jul;35(5):515-24
biotin-geranylpyrophosphate  0   *Polyisoprenyl Phosphates Biotin/*analogs & derivatives. Nat Chem Biol 2009 Apr;5(4):227-35
biotinylated linoleoylglycerylphosphatidylcholine  0   *Biotin *Phosphatidylcholines. J Proteome Res 2008 Oct;7(10):4237-46
B 10330  0   Biotin/*analogs & derivatives Bradykinin/*analogs & derivatives. Peptides 2008 Sep;29(9):1626-30
trifluoroacetyl(alpha,alpha-diethyl)Gly-Lys(Nepsilonbiotin)-(D)Lys-Cys  0   *Oligopeptides Biotin/*analogs & derivatives. Anal Chem 2007 Mar 1;79(5):1932-8
DPPB compound  0   *Phosphatidylcholines Biotin/*analogs & derivatives. Chem Res Toxicol. 2007 Feb;20(2):227-34
PLPB compound  0   *Phosphatidylcholines Biotin/*analogs & derivatives. Chem Res Toxicol. 2007 Feb;20(2):227-34
N'-aminooxymethylcarbonylhydrazino D-biotin  0   *Hydrazines Biotin/*analogs & derivatives. Anal Chem. 2006 Oct 1;78(19):6847-54
iminobiotin  0   Biotin/*analogs & derivatives. Anal Sci. 2005 Aug;21(8):897-900
biotinylcysteic acid  0   Biotin/*analogs & derivatives Cysteic Acid/*analogs & derivatives. Anal Chem 2005 Jan 15;77(2):645-51
rhenium(I) amidodipyridoquinoxaline biotin  0   *Organometallic Compounds Biotin/*analogs & derivatives Rhenium. Inorg Chem. 2006 Feb 20;45(4):1714-22
biotin-BSA-GdDTPA  0   *Biotin *Pentetic Acid *Serum Albumin, Bovine. Magn Reson Med 2006 May;55(5):1013-22
hydroxysuccinimidyl-poly(ethylene glycol)-biotin  0   *Polyethylene Glycols Biotin/*analogs & derivatives. J Control Release 2006 Mar 10;111(1-2):135-44
z-VK(biotin)D(OMe)-fmk  0   *Dipeptides Biotin/*analogs & derivatives. Anal Biochem. 2006 Mar 1;350(1):32-40
2-(biotinamido)ethanethiol  0   Biotin/*analogs & derivatives Cysteamine/*analogs & derivatives. Colloids Surf B Biointerfaces 2006 Jan 15;47(1):107-11
dibiotinylated aluminum sulfophthalocyanine  0   *Indoles Biotin/*analogs & derivatives. J Photochem Photobiol B 2005 Jul 1;80(1):57-64
diphenyl 4-amidino-alpha-(biotinyl-6-aminohexanamido)benzylphosphonate  0   *Phosphonic Acids Biotin/*analogs & derivatives. J Mol Recognit 2005 Jul-Aug;18(4):295-306
9-(2-biotinylamidoethyl)carboxylate-10-methylacridinium  0   *Acridines Biotin/*analogs & derivatives. Clin Chim Acta 2005 Jul 24;357(2):159-67
9-(2-biotinyloxyethyl)carboxylate-10-methylacridinium  0   *Acridines Biotin/*analogs & derivatives. Clin Chim Acta 2005 Jul 24;357(2):159-67
biotinylated hen's egg sialyl glycopeptide  0   *Oligosaccharides Biotin/*analogs & derivatives. Chem Commun (Camb) 2004 Dec 7;(23):2692-3
4-(3-(biotinamido)propynyl)-2-oxo(1H)pyridin-3-ylribofuranosyl triphosphate  0   *Nucleosides Biotin/*analogs & derivatives. Nucleic Acids Res 2005;33(15):e129
rhodamin-biotin distearylphosphatidylethanolamine  0   *Phosphatidylethanolamines *Rhodamines Biotin/*analogs & derivatives. Chem Phys Lipids 2005 Feb;133(2):215-23
N-(6-(biotinamido)hexyl)-3'-(2'-pyridyldithio)propionamide  0   *Disulfides Biotin/*analogs & derivatives. Biochem Biophys Res Commun 2005 May 20;330(4):1224-9
biotinylated sulfo-Lewis A derivatized polyacrylamide  0   *Acrylamides Biotin/*analogs & derivatives. Circulation 2005 Jan 4;111(1):106-12
biotin-phosmidosine (O-ethyl ester) conjugate  0   *Biotin *Purine Nucleotides. Bioorg Med Chem 2004 Dec 15;12(24):6343-9
5-(3-(1-(5-(5-(biotinylamino)pentanamidomethyl)-2-nitrophenyl)ethoxycarbonylamino)propenyl)-2'-deoxyuracil 5'-triphosphate  0   *Deoxyuracil Nucleotides Biotin/*analogs & derivatives. Nucleic Acids Res 2004;32(2):535-41
N-(13-biotinamido-4,7,10-trioxatridecanyl) tert-butyloxy carbamide  0   *Carbamates Biotin/*analogs & derivatives. Bioconjug Chem 2004 Jan-Feb;15(1):224-30
biotinyl-3,6,9-trioxaundecanediamine  0   Biotin/*analogs & derivatives. J Pharm Sci 2003 May;92(5):933-7
1-biotinamido-4-(4'-(maleimidomethyl)cyclohexanecarboxamido)butane  0   Biotin/*analogs & derivatives. Prostaglandins Leukot Essent Fatty Acids 2003 Apr;68(4);273-84
technetium 99m DTPA-bisbiotin  0   *Organotechnetium Compounds Biotin/*analogs & derivatives. Nucl Med Biol 2003 Feb;30(2):135-40
copper-64-DOTA-biotin  0   *Organometallic Compounds Biotin/*analogs & derivatives Copper Radioisotopes. J Nucl Med 2003 Aug;44(8):1284-92
diaminobiotin  0   Biotin/*analogs & derivatives. J Nutr. 2003 May;133(5):1259-64
streptaphage  0   Biotin/*analogs & derivatives Cholesterol/*analogs & derivatives. J Am Chem Soc 2002 Jun 5;124(22):6265-73
oxybiotin  0   Biotin/*analogs & derivatives. Carbohydr Res 2002 Mar 1;337(5):459-65
TBL(4)K compound  0   *Azirines Biotin/*analogs & derivatives. Science 2002 Jun 21;296(5576):2215-8
6-biotin-17-nicotinamide-adenine-dinucleotide  0   Biotin/*analogs & derivatives NAD/*analogs & derivatives. J Histochem Cytochem 2002 Jan;50(1):91-8
N-(5-azido-2-nitrobenzoyl)-N'-biotinyl-1,2-diaminoethane  0   Biotin/*analogs & derivatives. J Photochem Photobiol B 2001 Aug 15;61(1-2):68-77
8-N(3)-3'-biotinyl-ATP  0   Adenosine Triphosphate/*analogs & derivatives Biotin/*analogs & derivatives. Biochem Biophys Res Commun 2001 Sep 7;286(5):1218-27
NEPP6-biotin  0   *Prostaglandins Biotin/*analogs & derivatives. J Neurochem 2001 Apr;77(1):50-62
RP 488  0   *Organotechnetium Compounds Biotin/*analogs & derivatives. Nucl Med Biol 2000 Nov;27(8):803-13
N-biotinylaminoethyl methanethiosulfonate  0   Biotin/*analogs & derivatives. J Neurosci 2001 Jan 1;21(1):67-74
biotin-aminohexylamino-glycyl-glycyl-leucyl-epoxysuccinyl-leucyl-proline  0   *Oligopeptides Biotin/*analogs & derivatives Affinity Labels.
biotin-tyrosyl-valyl-alanyl-aspartic acid aldehyde  0   *Oligopeptides Biotin/*analogs & derivatives. J Leukoc Biol 2000 Jul;68(1):87-96
biotin methyl ester  608-16-2   Biotin/*analogs & derivatives. Anal Chem 2000 Jun 1;72(11):2418-22
4-(2-(2-(2-(biotinylamino)ethoxy)ethoxy)ethoxy)aminocarbonyl-2-diphenylphosphinobenzoic acid  0   *Phosphines Biotin/*analogs & derivatives. Science 2000 Mar 17;287(5460):2007-10
DOTA-biotin  0   *Organometallic Compounds Biotin/*analogs & derivatives Yttrium Radioisotopes. Clin Cancer Res 2000 Feb;6(2):406-14
N-(((6-biotinoyl)amino)hexanoyl)-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine  0   *Phosphatidylethanolamines Biotin/*analogs & derivatives. Biophys J 2000 Jan;78(1):487-98
10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide  0   *Organophosphorus Compounds Biotin/*analogs & derivatives. Proc Natl Acad Sci U S A 1999 Dec 21;96(26):14694-9
biotinylhydrazido 7-(3-((((((4-azidophenyl)propylcarbonyl)amino)acetyl)amino)methyl)-7-oxabicyclo(2.2.1)hept-2-yl)-5-heptenoate  0   *Azides Biotin/*analogs & derivatives. Bioorg Med Chem Lett 1999 Oct 18;9(20):2963-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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