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NAD

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Definition: A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)  a coenzyme; NAD or NADP probably correct for indexing of pyridine nucleotides    Other names DPN; Nicotinamide-Adenine Dinucleotide; Nadide; Diphosphopyridine Nucleotide; Coenzyme I; NADH; Nucleotide, Diphosphopyridine; Nicotinamide Adenine Dinucleotide; Dinucleotide, Nicotinamide-Adenine; Dinucleotide, Dihydronicotinamide Adenine; Adenine Dinucleotide, Dihydronicotinamide; Dihydronicotinamide Adenine Dinucleotide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-picolyl azide adenine dinucleotide  0   NAD/*analogs & derivatives. J Phys Chem B. 2012 Jan 12;116(1):542-8.
nadcin  0   *NAD *Inosine Drug Combinations. Bull Exp Biol Med 2008 Sep;146(3):321-4
isonicotinyl-NAD  0   Isoniazid/*analogs & derivatives NAD/*analogs & derivatives. Novartis Found Symp 1998;217:209-20
nicotinamide 2-fluoroadenine dinucleotide  0   NAD/*analogs & derivatives. Biochemistry 2007 Apr 3;46(13):4100-9
energostim  0   *NAD *Inosine *Cytochromes c Drug Combinations. Bull Exp Biol Med 2003 Sep;136(3):253-6
1-benzyl-1,4-dihydronicotinamide  0   NAD/*analogs & derivatives. Bioorg Chem 2001 Feb;29(1):14-8
6-biotin-17-nicotinamide-adenine-dinucleotide  0   Biotin/*analogs & derivatives NAD/*analogs & derivatives. J Histochem Cytochem 2002 Jan;50(1):91-8
2'-deoxy-2'-aminoribo-NAD  0   NAD/*analogs & derivatives. Biochem J 2001 Sep 1;358(Pt 2):399-406
N(6)-(((N-(N-biotinyl-(ethenoaminocapronyl))-(6-aminohexyl))-carbamoyl)methyl)NAD  0   Biotin/*analogs & derivatives NAD/*analogs & derivatives. Arch Biochem Biophys 1997 Nov 15;347(2):155-62
P-(1-(4,5-dimethoxy-2-nitrophenyl)ethyl) nicotinamide adenine dinucleotide  0   NAD/*analogs & derivatives. Biochemistry 1997 Jul 22;36(29):9035-44
8-(N-(N-biotinyl)-8-aminohexylamino)NAD  0   Biotin/*analogs & derivatives NAD/*analogs & derivatives. Methods Enzymol 1997;280:255-65
N(6)-(N-(N-biotinyl)-6-aminohexylcarbamoylmethyl)NAD  0   Biotin/*analogs & derivatives NAD/*analogs & derivatives. Methods Enzymol 1997;280:255-65
nicotinamide guanine dinucleotide  5624-35-1   *Guanine Nucleotides NAD/*analogs & derivatives. FEBS Lett 1996 Nov 11;397(1):17-21
8-azidoadenosyl pseudocarba-NAD+  0   NAD/*analogs & derivatives. Biochem Biophys Res Commun 1996 Nov 1;128(1):128-33
8-azidoadenosyl carba-NAD+  0   NAD/*analogs & derivatives. Biochem Biophys Res Commun 1996 Nov 1;228(1):128-33
5-ribofuranosylpicolinamide adenine dinucleotide  0   NAD/*analogs & derivatives. Biochemistry 1994 Oct 4;33(39):11734-44
5-ribofuranosylnicotinamide adenine dinucleotide  0   NAD/*analogs & derivatives. Biochemistry 1994 Oct 4;33(39):11734-44
8-(4-bromo-2,3-dioxobutylthio)NAD  154591-46-5 Adenosine 5'-(trihydrogen (diphosphate)), 8-((4-bromo-2,3-dioxobutyl)thio)-, P'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, inner salt  NAD/*analogs & derivatives Isocitrate Dehydrogenase. Arch Biochem Biophys 1994 Feb 1;308(2):357-66
digoxigenin-conjugated NAD  0   *NAD *Digoxigenin. FEBS Lett 1994 Feb 7;338(3):264-6
3-pyridylacryloamide adenine dinucleotide  63293-07-2   NAD/*analogs & derivatives. Anal Biochem 1991;195(1):57
nicotinamide 8-azidoadenine dinucleotide  134388-69-5   *Azides NAD/*analogs & derivatives. Biochemistry 1991;30(28):6942
dextran-NAD  0   *NAD *Dextrans. Appl Biochem Biotechnol 1990;26(2):115
P(1)-N(6)-(4-azidophenylethyl)adenosine-P(2)-(4-(3-azidopyridinio)butyl)diphosphate  132210-01-6   *Azides NAD/*analogs & derivatives. Z Naturforsch (C) 1990;45(9-10):1044
nicotinamide 2-azidoadenine dinucleotide  126609-61-8   *Azides NAD/*analogs & derivatives. Proc Natl Acad Sci USA 1990;87(2):1243
adenosine-5'-mononicotinate  17274-96-3   NAD/*analogs & derivatives. Acta Crystallogr C 1988;44(Pt 12):2140
6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide  54298-36-1   NAD/*analogs & derivatives. Biochemistry 1988;27(19):7371
3'-deoxynicotinamide adenine dinucleotide  60902-13-8   NAD/*analogs & derivatives. J Biol Chem 1988;263(33):17690
nicotinamide-adenine dinucleotide 2',3'-dialdehyde  117017-91-1   NAD/*analogs & derivatives. Arch Biochem Biophys 1988;264(2):665
carbanicotinamide adenine dinucleotide  112345-60-5   NAD/*analogs & derivatives. Biochemistry 1988;27(1):183
nicotinamide arabinoside adenine dinucleotide  108646-17-9   NAD/*analogs & derivatives. Biochemistry 1987;26(12):3453
3-(4-(reduced 3-pyridine aldehyde-adenine dinucleotide))pyruvate  110241-41-3   NAD/*analogs & derivatives. J Neurochem 1987;48(6):1925
NAD-pyruvate adduct  0   *Pyruvates NAD/*analogs & derivatives. Dokl Akad Nauk SSSR 1986;289(4):996
3-benzoylpyridine-adenine dinucleotide  104076-88-2   NAD/*analogs & derivatives Coenzymes. Eur J Biochem 1986;159(2):375
3,4-dimethylpyridine adenine dinucleotide  102686-21-5   NAD/*analogs & derivatives. Biochim Biophys Acta 1986;886(1):64
3-((3-carboxy-3-oxopropyl)aminocarbonyl)-1,4-adenine dinucleotide  0   NAD/*analogs & derivatives. Hoppe Seylers Z Physiol Chem 1984;365(8):877
adenosine 5'-(alpha-thio)diphospho-5'-ribofuranosylnicotinamide  90024-63-8 Adenosine, N-((phenylmethoxy)carbonyl)glycylglycyl-N-(4-nitrophenyl)-, (S)  NAD/*analogs & derivatives. Eur J Biochem 1984;140(3):531
N-4-azido-2-nitrophenyl-4-aminobutyryl-NAD  88255-98-5 Adenosine 5'--(trihydrogen diphosphate), 3'-(4-((4-azido-2-nitrophenyl)amino)butanoate), 5'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt  *Azides NAD/*analogs & derivatives. Biochem J 1983;216(2):443
nicotinamide-8-bromoadenine dinucleotide  52977-37-4   NAD/*analogs & derivatives. Biochemistry 1983;22(19):4437
NADH-peroxide  0   NAD/*analogs & derivatives. J Biol Chem 1982;257(12):6809
5-methylnicotinamide-adenine dinucleotide  56541-76-5   NAD/*analogs & derivatives. Eur J Biochem 1981;118(3):479
3-chloroacetylpyridine-adenine dinucleotide  39938-03-9 Adenosine 5'-((trihydrogen)diphosphate), 5'-5'-ester with 3-(chloroacetyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt  NAD/*analogs & derivatives. Eur J Biochem 1981;119(2):311
NAD dimers  66844-06-2 Adenosine 5'-(trihydrogen-diphosphate), 5'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt, dimer  NAD/*analogs & derivatives. Biochim Biophys Acta 1981;661(1):120
nicotinamide-hypoxanthine dinucleotide  22052-73-9   NAD/*analogs & derivatives. Biochim Biophys Acta 1981;637(1):43
dihydronicotinamide formycin dinucleotide  74927-11-0 D-Ribitol, 1-C-(7-amino-1H-pyrazolo(4,3-d)pyrimidin-3-yl)-1,4-anhydro-, 5-(trihydrogen diphosphate), 5-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide, (S)  NAD/*analogs & derivatives. FEBS Lett 1980;116(1):41
3-azidopyridine-adenine dinucleotide  50695-15-3 adenosine 5'-(trihydrogen diphosphate) 5-5'-ester with 3-azido-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt  NAD/*analogs & derivatives. Ann NY Acad Sci 1980;346:104
NAD degrading enzyme  EC 3.-   NAD *Hydrolases. Biochem J 175(2):669;1978
1,4,5,6-tetrahydronicotinamide adenine dinucleotide  31172-31-3 adenosine 5'-(trihydrogen diphosphate), 5'-5'-ester with 1,4,5,6-tetrahydro-1-beta-D- ribofuranosyl-3-pyridinecarboxamide  NAD/*analogs & derivatives. Eur J Biochem 100(1):203;1979
2'-deoxynicotinamide adenine dinucleotide  6697-37-6 2'-deoxyadenosine 5'-(trihydrogen diphosphate), 5'-5'-ester with 3-(aminocarbonyl)-1-beta- D-ribofuranosylpyridinium hydroxide, inner salt  NAD/*analogs & derivatives. Biochemistry 18(17):3749;1979
arylazido-beta-alanyl-NAD  0 A3'-O-(3-(N-(4-azido-2-nitrophenyl)amino)propionyl)NAD  *Azides NAD/*analogs & derivatives. J Biol Chem 252(24):8990;l977; J Biol Chem 254(15):7220;1979
nicotinamide-6(2-aminoethylamino)purine dinucleotide  59587-50-7 Adenosine-5'-(trihydrogen diphosphate), N-(2-aminoethyl)-, 5'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt  NAD/*analogs & derivatives. Enzyme labelled immunoassy of hormones and drugs QW 25 I61e:67;1978
3-iodopyridine-adenine dinucleotide  56541-70-9 Adenosine 5'-((trihydrogen diphosphate)), 5'-5'-ester with 3-iodo-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt  NAD/*analogs & derivatives. Biochem Soc Trans 6(6):1276;1978
N(2),N(2)'-adipodihydrazido-bis-(N(6)-carbonylmethyl-NAD)  69861-86-5 Hexanedioic acid, bis(2-(((9-(5-O-(hydroxy(phosphonooxy)phosphinyl)-beta-D-ribofuranosyl)-9H-purin-6-yl)amino)acetyl)hydrazide), P'-5',P'''-5'''-diester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, bis(inner salt)  NAD/*analogs & derivatives. FEBS Lett 98(2):333;1979
5-(3-carboxy-3-hydroxypropyl)nicotinamide adenine dinucleotide  68889-85-0 Adenosine-- 5'-(trihydrogen diphosphate), 5'-5'-ester with 3-(aminocarbonyl)-5-(3-carboxy-3-hydroxypropyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt, (S)  NAD/*analogs & derivatives. Biochemistry 17(22):4621;1978
nicotinic acid adenine dinucleotide  6450-77-7   NAD/*analogs & derivatives. J Biochem (Tokyo) 84(3):687;1978
NAD sulfite  0   NAD/*analogs & derivatives. Biochem J 173(3):958;1978
phenyladenine dinucleotide  68134-82-7 Adenosine 5'-(trihydrogen--diphosphate), 5'-5-ester with (S)-1,4-anhydro-1-C-phenyl-D-ribitol  NAD/*analogs & derivatives. J Biol Chem 253(17):5886;1978
nicotinamide-benzimidazole dinucleotide  606-77-9   NAD/*analogs & derivatives. Biochem J 173(2):597;1978
diazoaminopyridine dinucleotide  42919-10-8 Adenosine 5'-(-trihydrogen diphosphate), 5'-5'-ester with 3-diazonio-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt  NAD/*analogs & derivatives. Arch Biochem Biophys 188(1):214;1978
3-chloroacetyl pyridinium dinucleotide  0   NAD/*analogs & derivatives. Biochim Biophys Acta 525(1):3;1978
N-6-(N-(6-aminohexyl)carbamoylmethyl)-NAD  52213-58-8 Adenosine 5'-(tri-hydrogen diphosphate), N-(2-((6-aminohexyl)amino)-2-oxoethyl)-, 5'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt  NAD/*analogs & derivatives. Europ J Biochem 86:455;1978
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