encyclopedia of medical concepts
ψ 
ψ 
ψ 

Inosine

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Definition: A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)     
Examples Didanosine; Inosine Pranobex; Thioinosine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
INS45973  0   Inosine/*analogs & derivatives Uridine Triphosphate/*analogs & derivatives. Am J Physiol Regul Integr Comp Physiol. 2011 Aug;301(2):R510-8
4'-azidoinosine  0   *Azides Inosine/*analogs & derivatives. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3122-4
N1-3-fluorophenyl-inosine  0   Inosine/*analogs & derivatives. Antiviral Res 2009 Jul;83(1):80-5
nadcin  0   *NAD *Inosine Drug Combinations. Bull Exp Biol Med 2008 Sep;146(3):321-4
7-deaza-2'-deoxyinosine  0   Inosine/*analogs & derivatives Nucleosides. Acta Crystallogr C. 2008 Aug;64(Pt 8):o417-9
tetrakis(inosine)platinum(II)  0   *Organoplatinum Compounds Inosine/*analogs & derivatives. Org Biomol Chem 2008 Aug 21;6(16):2892-9
2-fluoro-6-O-(trimethylsilylethyl)-2'-deoxyinosine  0   *Trimethylsilyl Compounds Inosine/*analogs & derivatives. Curr Protoc Nucleic Acid Chem. 2001 May;Chapter 1():Unit 1.3
N-1-dinitrophenyl-inosine  0   Inosine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1649-52
9-(2,3,5-trideoxypentofuranosyl)-9H-purin-6-one  0   Inosine/*analogs & derivatives. J Pharm Biomed Anal 2007 Nov 5;45(3):516-20
5'-deoxy-5'-fluoroinosine  0   Inosine/*analogs & derivatives. J Org Chem. 2007 Oct 26;72(22):8551-4
8-oxoinosine  0   Inosine/*analogs & derivatives. Chemistry 2007;13(12):3441-9
5'-chloro-5'-deoxyinosine  0   Inosine/*analogs & derivatives. Angew Chem Int Ed Engl. 2006 Jan 23;45(5):759-62
5'-O-tritylinosine  0   *Trityl Compounds Inosine/*analogs & derivatives Thymidine Phosphorylase/antagonists & inhibitors. J Med Chem 2006 Sep 7;49(18):5562-70
5'-fluoro-5-deoxyinosine  0   Inosine/*analogs & derivatives. Bioorg Chem 2005 Oct;33(5):393-401
N(1)-(2,4-dinitrophenyl)-2'-deoxyinosine phosphoramidite  0   Inosine/*analogs & derivatives 2,4-Dinitrophenol/*analogs & derivatives. Nucleic Acids Res 2005;33(6):1767-78
N(1)-(2,4-dinitrophenyl)-2'-deoxyinosine  0   Inosine/*analogs & derivatives 2,4-Dinitrophenol/*analogs & derivatives. Nucleic Acids Res 2005;33(6):1767-78
7,8-dihydro-8-oxo-2'-deoxyinosine  0   Inosine/*analogs & derivatives. Nucleic Acids Res 2005;33(5) (dup#3):1637-43
energostim  0   *NAD *Inosine *Cytochromes c Drug Combinations. Bull Exp Biol Med 2003 Sep;136(3):253-6
shimofuridin A  0   *Furans Inosine/*analogs & derivatives. Carbohydr Res. 2003 Jan 2;338(1):55-60
8-chloro-inosine  0   Inosine/*analogs & derivatives. Cancer Chemother Pharmacol 2002 Aug;50(2):85-94
8-aza-7-deaza-2'-deoxyisoinosine  0   Inosine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2000 Oct-Dec;19(10-12):1581-98
1-glucopyranosylinosine-5',6'-diphosphate  0   *Glucosides Inosine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2000 Aug;19(8):1281-8
1-benzyl-2'-deoxyinosine  0   Inosine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2000 Jul;19(7):1135-43
2-azido-2'-deoxyinosine  0   *Azides Inosine/*analogs & derivatives. Biol Chem 1998 Apr-May;379(4-5):527-33
2-fluoro-(O(6)-trimethylsilylelthyl)-2'-deoxyinosine  151900-41-3   *Trimethylsilyl Compounds Inosine/*analogs & derivatives. Chem Res Toxicol 1996 Apr-May;9(3):630-7
albuside B  0   Inosine/*analogs & derivatives. FEBS Lett 1995 Aug 7;369(2-3):221-4
2'-deoxyisoinosine  0   Inosine/*analogs & derivatives. Nucleic Acids Res 1995 Jul 11;23(13):2499-505
3-ribofuranosyl-6,7-dihydro-9H-thiazolo(3,2-a)purin-9-one  52538-20-2   Inosine/*analogs & derivatives. Acta Crystallogr C 1994 May 15;50(Pt 5):734-6
6-isoinosine  0   Inosine/*analogs & derivatives. Chung Kuo Cung Yao Tsa Chih 1993 Mar;18(3):162-4
triptosine  86248-47-7 L-Tryptophan, 5-hydroxy-, compd. with inosine (1:1)  *5-Hydroxytryptophan *Inosine Drug Combinations. Alcohol Alcohol 1992 May;27(3):273-6
3'-deoxy-3'-fluoroinosine  117517-20-1   Inosine/*analogs & derivatives. Nucleic Acids Symp Ser 1990;(22):23
3'-deoxyinosine  13146-72-0   Inosine/*analogs & derivatives. Biochem Pharmacol 1991;42(2):207
3-isoinosine  6835-54-7 6H-Purin-6-one, 3,7-dihydro-3-beta-D-ribofuranosyl  Inosine/*analogs & derivatives Isomerism. Acta Crystallogr C 1989;45(Pt 9):1394
erythropifaden  128523-71-7   *Adenine *Inosine Drug Combinations. Fiziol Zh 1989;35(4):15
PIGPA solution  0   *Glucose *Inosine *Phosphates *Pyruvates Blood Preservation. Beitr Infusionther 1988;21:64
S-inosylhomocysteine  22365-14-6 Inosine, 5'-S-(3-amino-3-carboxypropyl)-5'-thio  Homocysteine/*analogs & derivatives Inosine/*analogs & derivatives. J Bacteriol 1988;170(9):4376
5'-(4-fluorosulfonylbenzoyl)inosine  83133-70-4   Inosine/*analogs & derivatives Proton-Translocating ATPases/antagonists & inhibitors. J Biol Chem 1986;261(30):14171
inosine 5'-(3-thiotriphosphate)  77065-87-3   Inosine/*analogs & derivatives. Biochemistry 1986;25(19):5571
7-deazainosine  2862-16-0   Inosine/*analogs & derivatives. Nucleic Acids Res 1986;14(16):6579
9-deazainosine  89458-19-5   Inosine/*analogs & derivatives. J Infect Dis 1986;154(2):323
5'-deoxy-5'-iodo-9-deazainosine  102731-46-4   Inosine/*analogs & derivatives Purine-Nucleoside Phosphorylase/antagonists & inhibitors. Cancer Res 1986;46(4 Pt 1):1774
carbocyclic inosine  16975-94-3 6H-Purin-6-one, 9-(2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)-1,9-dihydro-, (1S-(1alpha,2beta,3beta,4alpha))  Inosine/*analogs & derivatives. Biochem Biophys Res Commun 1986;134(3):1114
7-beta-ribofuranosylhypoxanthine  10280-01-0   *Inosine Isomerism. Cancer Res 1985;45(11 Pt 2):5643
7-(6'-deoxytalofuranosyl)hypoxanthine  86527-19-7   Inosine/*analogs & derivatives. J Med Chem 1983;26(10):1527
9-(6'-deoxytalofuranosyl)hypoxanthine  86527-20-0   Inosine/*analogs & derivatives. J Med Chem 1983;26(10):1527
7-(6-deoxy-beta-D-allofuranosyl)hypoxanthine  85421-85-8   Inosine/*analogs & derivatives. J Med Chem 1983;26(7):1071
9-(6'-deoxy-beta-D-allofuranosyl)hypoxanthine  85421-86-9   Inosine/*analogs & derivatives. J Med Chem 1983;26(7):1071
7-methylinosine  20245-33-4   Inosine/*analogs & derivatives. Science 1982;217(4554):77
neplanocin D  72877-47-5   Inosine/analogs & derivatives. Nucleic Acids Symp Ser 1980;(8):s65
2'-amino-2'deoxy-2-chloroinosine  76727-51-0 Inosine, 2'-amino-2'-deoxy-2-chloro  Inosine/*analogs & derivatives. Nucleic Acids Symp Ser 1980;(8):s11
2'-deoxy-2'-fluoroinosine  80049-87-2 Inosine, 2'-deoxy-2'-fluoro  Inosine/*analogs & derivatives. Nucleic Acids Res 1981;9(3):711
2'-amino-2'-deoxyinosine  75763-51-8 Inosine, 2'-amino-2'-deoxy  Inosine/*analogs & derivatives. FEBS Lett 1980;119(1):101
5'-deoxyinosine dialdehyde  71671-62-0 9H-Purine-9-acetaldehyde, 1,6-dihydro-alpha-(1-methyl-2-oxoethoxy)-6-oxo-, (R-(R*,R*))  Inosine/*analogs & derivatives. Biochem Pharmacol 28(6):867;1979
1-methylinosine  2140-73-0   Inosine/*analogs & derivatives. Cancer 41(5):1685;1978; Clin Chim Acta 1979;97(2-3):159; J Am Chem Soc 98(9):2641;1976; Monogr Hum Genet 10:135;1978
deoxyinosine  890-38-0   Inosine/*analogs & derivatives. Acta Chem Scand (B) 1979;B33(5):384; Biochem J 154(1):77;1976; Rev Esp Fisiol 32(3):193;1976
inosine dialdehyde  23590-99-0 alpha-(hydroxymethyl)-alpha'-(6-hydroxy-9H-purin-9-yl) diglycolaldehyde  Inosine/*analogs & derivatives. Cancer Chemother Rep (Part 1) 58(2):149;1974; Cancer Chemother Rep (Part 1) 59(4):685;1975; Cancer Chemother Rep (Part 1) 59(5):1007;1975; Cancer Res 1979;39(11):4600; Cancer Res 36(9):3166;1976; Cancer Res 37:2188;1977; Cancer Res 38:815;1978; J Med 8(3&4):239;1977; J Nat Can Inst 61(5):1307;1978
8-azainosine  4968-68-7   Inosine/*analogs & derivatives. Cancer Res 33(3):465;1973; J Med Chem 20(1):116;1977

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