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Factor XI

More information in Books or onNLM PubMed
Definition: Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C.  a blood coag factor   
See Also Coagulants
Examples Factor XIa 		Other names Plasma Thromboplastin Antecedent; Coagulation Factor XI; XI, Coagulation Factor; Thromboplastin Antecedent, Plasma; Factor XI, Coagulation; Antecedent, Plasma Thromboplastin; Blood Coagulation Factor XI
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
EP 224283  0   *Oligosaccharides Biotin/*analogs & derivatives Factor XI/antagonists & inhibitors Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors. J Pharmacol Exp Ther 2011 Aug;338(2):412-20
2-(2-hydroxybiphenyl-3-yl)-1H-indole-5-carboxamidine  0   *Amidines *Indoles Factor XI/antagonists & inhibitors Urokinase-Type Plasminogen Activator/antagonists & inhibitors. J Med Chem 2001 Aug 16;44(17):2753-71
2-(3-bromo-2-hydroxy-5-methylphenyl)-1H-indole-5-carboxamidine  0   *Amidines *Indoles Factor XI/antagonists & inhibitors Urokinase-Type Plasminogen Activator/antagonists & inhibitors. J Med Chem 2001 Aug 16;44(17):2753-71

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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