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Pyridoxal Phosphate

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Definition: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).  deficiency: coordinate PYRIDOXAL PHOSPHATE /defic (IM) with VITAMIN B 6 DEFICIENCY (IM)   
Pharmacological Action Vitamin B Complex 		Other names Pyridoxal P; Pyridoxal 5 Phosphate; Phosphate, Pyridoxal; Pyridoxal-P; Pyridoxal 5-Phosphate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MRS 2211  0   *Azo Compounds Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2. Am J Physiol Cell Physiol 2011 Feb;300(2):266-75
N-phosphopyridoxyl-alpha-aminoadipate  0   Pyridoxal Phosphate/*analogs & derivatives 2-Aminoadipic Acid/*analogs & derivatives. Proteins 2009 May 1;75(2):348-59
N-phosphopyridoxylleucine  0   Leucine/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives. Proteins 2009 May 1;75(2):348-59
phosphopyridoxylalanine  0   Alanine/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives. Acta Crystallogr D Biol Crystallogr 2005 Apr;61(Pt 4):472-6
4'-O-methylpyridoxine-5'-phosphate  0   Pyridoxal Phosphate/*analogs & derivatives. J Med Chem 2001 Sep 13;44(19):3166-74
6-((4,6,8-trisulfo-1-naphthyl)iminocarbonyl-1,3-(4-methylphenylene)iminocarbonyl-1,3-phenyleneazo)pyridoxal-5'-phosphate  0   Pyridoxal Phosphate/*analogs & derivatives Suramin/*analogs & derivatives Receptors, Purinergic P2. J Auton Nerv Syst 2000 Jul 3;81(1-3):171-7
pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate)  0   *Sulfonic Acids Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. Eur J Pharmacol 2000 Jan 17;387(3):R19-R21
MRS 2220  0   *Azo Compounds Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. J Med Chem 1998 Jun 18;41(13):2201-6
MRS 2219  0   Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2/agonists. J Med Chem 1998 Jun 18;41(13):2201-6
6-N-(5'-phosphopyridoxyl)-2-N-acetyl-lysine methyl ester  0   Lysine/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives. J Photochem Photobiol B 1996 Jan;32(1-2):71-9
N-methylpyridoxal-5'-phosphate  0   Pyridoxal Phosphate/*analogs & derivatives. J Biol Chem 1995 May 19;270(20):11797-802
5'-phosphopyridoxyl-7-azatryptophan  157117-38-9   Pyridoxal Phosphate/*analogs & derivatives Tryptophan/*analogs & derivatives. Biochem Biophys Res Commun 1994 Feb 15;198(3):1007-11
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid  149017-66-3   Pyridoxal Phosphate/*analogs & derivatives.
Pharma Action Platelet Aggregation Inhibitors 		Eur J Pharmacol 1992 Jul 7;217(2-3):217-9
bispyridoxal tetraphosphate  118446-89-2   Pyridoxal Phosphate/*analogs & derivatives. J Protein Chem 1991 Oct;10(5):503-10
uridine triphosphopyridoxal  135145-98-1   Pyridoxal Phosphate/*analogs & derivatives Uridine Triphosphate/*analogs & derivatives. Biochemistry 1991;30(35):8541
carbamoylpyridoxal 5'-phosphate  134121-41-8   Pyridoxal Phosphate/*analogs & derivatives. Biochim Biophys Acta 1991;1077(2):233
pyridoxyl 5'-phosphate hemoglobin A(0)  0   Hemoglobin A/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives Blood Substitutes. J Chromatogr 1990;532(1):55
manganese pyridoxal phosphate  0   *Organometallic Compounds *Pyridoxal Phosphate Magnetic Resonance Imaging Manganese. Invest Radiol 1990;25(Suppl 1):S74
pyridoxal phosphate, trisodium citrate, tromethamine drug combination  0   *Citrates *Pyridoxal Phosphate *Tromethamine Drug Combinations. Haematologica 1990;75(1):38
tetra(pyridoxal phosphate)thrombin  0   *Pyridoxal Phosphate *Thrombin. J Biol Chem 1989;264(19):11117
N,N'-bis(pyridoxal-5-phosphate)ethylenediamine-N,N'-diacetic acid  119797-12-5   Edetic Acid/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives Manganese.
Pharma Action Contrast Media 		Radiology 1989;172(1):59TESLASCAN
pyridoxal phosphate gamma-aminobutyric acid  63221-68-1   gamma-Aminobutyric Acid/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives. Farmakol Toksikol 1989;52(1):56
pyridoxal phosphate-6-azophenyl-2'-sulfonic acid  121864-87-7   Pyridoxal Phosphate/*analogs & derivatives. Biochem Biophys Acta 1988;945(1):11
3'-O-methylpyridoxal 5'-phosphate  21056-63-3   Pyridoxal Phosphate/*analogs & derivatives. J Biol Chem 1987;262(30):14422
pyridoxal 5'-diphospho-5'-adenosine  4500-99-6   Adenosine Diphosphate/*analogs & derivatives Pyridoxal Phosphate/*analogs & derivatives.
Pharma Action Affinity Labels 		J Biol Chem 1986;261(9):4126
sedalipid  62055-05-4   *Glutamine *Pyridoxal Phosphate. Fortschr Med 1985;103(43):1011
pyridoxal-5-phosphate semicarbazone  634-27-5   Pyridoxal Phosphate/*analogs & derivatives. J Chromatogr 1985;342(2):277
uridine diphosphopyridoxal  97654-04-1   Pyridoxal Phosphate/*analogs & derivatives Uridine Diphosphate/*analogs & derivatives. J Biol Chem 1985;260(11):6670
2-nor-2-formylpyridoxal-5'-phosphate  42253-87-2   Pyridoxal Phosphate/*analogs & derivatives. Adv Exp Med Biol 1984;180:345
N-4-azido-2-nitrophenylpyridoxyl-5-phosphate  95973-32-3 3-Pyridinemethanol, 4-(((4-azido-2-nitrophenyl)amino)methyl)-5-hydroxy-6-methyl-, cis-(+-)  *Azides Pyridoxal Phosphate/*analogs & derivatives. Biochem Biophys Res Commun 1985;127(1):346
6-fluoropyridoxal phosphate  90932-80-2   Pyridoxal Phosphate/*analogs & derivatives. J Biol Chem 1985;260(5):2709
pyridoxal 5'-phosphate-binding protein, human  0   *Carrier Proteins Pyridoxal Phosphate. Prog Clin Biol Res 1984;144A:11
4-vinylpyridoxal-5-phosphate  31383-64-9 3-Pyridinemethanol, 4-ethenyl-5-hydroxy-6-methyl-, alpha-(dihydrogen phosphate)  Pyridoxal Phosphate/*analogs & derivatives 4-Aminobutyrate Transaminase/antagonists & inhibitors. Eur J Biochem 1982;126(3):507
pyridoxal(5')diphospho(1)-glucose  80503-46-4 alpha-D-Glucopyranose, 1-(P'-((4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl) dihydrogen diphosphate), disodium salt  Pyridoxal Phosphate/*analogs & derivatives. J Biol Chem 1981;256(21):10759
polyhemoglobin-pyridoxal-5-phosphate  0   *Hemoglobins Pyridoxal Phosphate/*analogs & derivatives Blood Substitutes. Biul Eksp Biol Med 1981;91(3):311
pyridoxal phosphoglucose  77172-69-1 beta-D-Glucopyranose, 1-((4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl hydrogen phosphate)  Pyridoxal Phosphate/*analogs & derivatives. J Biol Chem 1980;256(2):728
pyridoxine 5-phosphate  447-05-2 3,4-pyridinedimethanol, 5-hydroxy-6-methyl-, alpha(3)-(dihydrogen phosphate)  Pyridoxal Phosphate/*analogs & derivatives. J Immunol Methods 1980;33(3):261
pyridoxal triphosphate  71510-36-6 Triphosphoric acid, P-((4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl) ester  Pyridoxal Phosphate/*analogs & derivatives. Mol Biol (Mosk) 13(4):811;1979
pyridoxal 5-thiophosphate  69245-32-5 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonothio)methyl)  Pyridoxal Phosphate/*analogs & derivatives. Mol Biol (Mosk) 13(4):912;1979
pyridoxal diphosphate  68385-44-4 Diphosphoric acid, mono((4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl) ester  Pyridoxal Phosphate/*analogs & derivatives. Mol Biol (Mosk) 13(4):811;1979
pyridoxal-5'-phosphate monomethyl ester  26210-16-2   Pyridoxal Phosphate/*analogs & derivatives. Biochem Biophys Res Commun 85(1):99;1978
P(1),P(2)-bis(5'-pyridoxal)diphosphate  67279-83-8 Diphosphoric acid, P,P'-bis((4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl) ester  Pyridoxal Phosphate/*analogs & derivatives. BBRC 82(2):462;1978
phosphorpyridoxyltrifluoroethylamine  59087-16-0 3-Pyridinemethanol, 5-hydroxy-6-methyl-4-(((2,2,2-trifluoroethyl)amino)methyl)-, alpha-(dihydrogen phosphate)  Pyridoxal Phosphate/*analogs & derivatives. J Biol Chem 251(7):1853;1976
pyridoxal phosphate oxime O-acetic acid  17780-81-3   Pyridoxal Phosphate/*analogs & derivatives. Brain Res 96(2):279;1975
pyridoxal phosphonate  32453-95-5   Pyridoxal Phosphate/*analogs & derivatives. J Med Chem 14(7):568;1971
2-nor-2-hydroxymethylpyridoxal 5'-phosphate  20885-15-8   Pyridoxal Phosphate/*analogs & derivatives. Biochim Biophys Acta 320(3):6485;1973
Pyrvanal  0   Pyridoxal Phosphate/*analogs & derivatives. Vestn Akad Med Nauk SSSR 26(11):40;1971
pyridoxal phosphate gamma-glutamyl hydrazone  14520-50-4   Pyridoxal Phosphate/*analogs & derivatives Glutamate Decarboxylase/antagonists & inhibitors.
4-deoxypyridoxine 5'-phosphate  883-84-1 5-hydroxy-4,6-dimethyl-3-pyridinemethanol 3- (dihydrogen phosphate)  Pyridoxal Phosphate/*analogs & derivatives. J Biol Chem 247(21):7097;1972

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