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Glycerol

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Definition: A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.     
Pharmacological Action Cryoprotective Agents; Solvents
Examples Glyceryl Ethers; Nitroglycerin 		Other names Glycerin; Glycerine; 1,2,3-Trihydroxypropane
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
glycerol phenylbutyrate  0   *Phenylbutyrates Glycerol/*analogs & derivatives. Mol Genet Metab. 2011 Aug;103(4):323-9.
6-O-methyl-D-glycero-alpha-L-gluco-heptopyranose  0   *Monosaccharides Glycerol/*analogs & derivatives. Org Lett. 2011 Oct 7;13(19):5290-3
ScaleA2 solution  0   *Urea Glycerol Tissue Fixation/methods. Nat Neurosci. 2011 Nov;14(11):1481-8
p-methylsulfonylphenylglycerol  0   *Sulfones Glycerol/*analogs & derivatives. Bioorg Med Chem Lett. 2011 Sep 15; 21(18):5583-8.
glyceryl-isoeugenol  0   *Eugenol *Glycerol Anti-Inflammatory Agents. Int J Immunopathol Pharmacol. 2011 Apr-Jun;24(2):345-56
polyglycerol 6-distearate  0   *Polymers Glycerol/*analogs & derivatives. Int J Pharm 2011 Mar 15;406(1-2):163-72
Poly-2p cream  0   *Glycerol *Phytosterols Dermatologic Agents. G Ital Dermatol Venereol. 2010 Dec;145(6):703-8
Proliferol  0   *Glucose *Glycerol *Lidocaine *Phenol Drug Combinations. Int J Toxicol. 2009 May-Jun;28(3):219-29
1, 3-dipalmitoyl-2-stearoyl-sn-glycerol  0   *Stearates Glycerol/*analogs & derivatives. Chem Phys Lipids. 2009 Jul;160(1):11-32
1,3-dimyristoyl-2-stearoyl-sn-glycerol  0   Glycerol/*analogs & derivatives. Chem Phys Lipids. 2008 Jul;154(1):7-18
1,2-dimyristoyl-3-stearoyl-sn-glycerol  0   *Stearates Glycerol/*analogs & derivatives. Chem Phys Lipids. 2008 Jul;154(1):7-18
glycerol 1,3-diglycerolate diacrylate  0   *Acrylates Glycerol/*analogs & derivatives. Int J Biol Macromol. 2008 Oct 1;43(3):307-13
polyglyceryl-6 isostearate  0   *Stearic Acids Glycerol/*analogs & derivatives. Int J Pharm 2008 Sep 1;361(1-2):41-6
gamma-linolenoyldilinoleoylglycerol  0   *Linolenic Acids Glycerol/*analogs & derivatives. Anal Chem. 2008 Aug 1;80(15):5788-93
Holisal  0   *Salicylates Cellulose/*analogs & derivatives Choline/*analogs & derivatives Glycerol/*analogs & derivatives. Georgian Med News 2008 Jan;(154):36-9
glycerol 1-stearate  0   *Stearates Glycerol/*analogs & derivatives. Nat Med (Tokyo) 2008 Jul;62(3):358-9
1,2-dipalmitoylglycerophosphorylethanolamine  0   *Ethanolamines Glycerol/*analogs & derivatives. Anal Sci. 2008 Feb;24(2):293-6
INA((R)-1-O-(1-pyrenylmethyl)glycerol)  0   *Pyrenes Glycerol/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1641-3
3-phenoxy-1,2-propanediol  0   Glycerol/*analogs & derivatives. Appl Microbiol Biotechnol 2007 Oct;76(6):1281-7
guaiacylglycerol 3-O-(6-O-p-coumaroyl)glucopyranoside  0   *Glucosides Glycerol/*analogs & derivatives. J Asian Nat Prod Res 2007 Apr-Aug;9(3-5):457-61
guaiacylglycerol 3-O-(6-O-p-hydroxybenzoyl)glucopyranoside  0   *Glucosides Glycerol/*analogs & derivatives. J Asian Nat Prod Res 2007 Apr-Aug;9(3-5):457-61
2-(2-ethoxy-4-formylphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propane-1,3-diol  0   *Benzaldehydes Glycerol/*analogs & derivatives. J Agric Food Chem 2007 Oct 31;55(22):9043-6
1,2-dipalmitoyl-glycerophosphatidyl-glycerol  0   *Palmitates Glycerol/*analogs & derivatives. J Phys Chem B 2007 Apr 12;111(14):3813-21
PG-NH2 compound  0   *Dendrimers Glycerol/*analogs & derivatives. J Biol Inorg Chem 2007 Mar;12(3):406-20
1-O-(9'-(1''-pyrenyl))nonylglycerol  0   *Pyrenes Glycerol/*analogs & derivatives. J Lipid Res 2006 Mar;47(3):633-42
LysoUB  0   *Coumarins *Ethylamines Glycerol/*analogs & derivatives. Anal Biochem. 2006 Jan 1;348(1):87-93
1,2-distearoyl-sn-glycero-3-phosphatoethanolamine-N-(amino(poly(ethylene glycol)))  0   *Ethylene Glycols Glycerol/*analogs & derivatives. Langmuir. 2004 Oct 12;20(21):9371-9
1,2-O-isopropylidene glycerol  0   Alkenes Glycerol/*analogs & derivatives. J Appl Microbiol. 2005;99(4):960-7
(R)-1-O-(4-(1-pyrenylethynyl)phenylmethyl)glycerol  0   *Pyrenes Glycerol/*analogs & derivatives. J Am Chem Soc. 2005 Oct 26;127(42):14849-58
1,2-O-(2'-hydroxyoctadecyl)glycerol  0   Glycerol/*analogs & derivatives. Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1476-8
1,2-di-O-stearoyl-3-O-(6-deoxy-6-sulfo-beta-D-glucopyranosyl)-sn-glycerol  0   *Monosaccharides Glycerol/*analogs & derivatives. Biochem Pharmacol. 2004 Dec 15;68(12):2379-86
Grafton demineralized bone matrix gel  0   *Glycerol. Spine 2004 Mar 15;29(6):660-6
5-((1,4-(dicarboxymethyl)-5-(2,3-dihydroxypropyl)-2-pyrrolo(3,2-b)pyrrolyl)methine)-1,4-(dicarboxymethyl)-2-(1,2,3-trihydroxypropyl)pyrrolo(3,2-b)pyrrolylium  0   *Pyrroles Glycerol/*analogs & derivatives. Biosci Biotechnol Biochem 2004 Jan;68(1):247-9
1,3-di-O-cinnamoyl-glycerol  0   *Cinnamates Glycerol/*analogs & derivatives Plant Extracts. Fitoterapia. 2004 Jun;75(3-4):423-5
glyceroyl N-acetyllactosaminide  0   Glycerol/*analogs & derivatives Lactose/*analogs & derivatives. Biosci Biotechnol Biochem 2003 Jul;67(7):1530-6
3-monochloropropane-1,2-diol  0   Glycerol/*analogs & derivatives. J Agric Food Chem. 2004 Apr 7;52(7):2059-66
dipyruvyl-acetyl-glycerol  0   Glycerol/*analogs & derivatives. Cardiovasc Drugs Ther. 2003 May;17(3):209-16
Man(4)K(3)DOG  0   *Oligosaccharides Glycerol/*analogs & derivatives. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2557-60
polyglycerol monostearate  0   *Stearates Glycerol/*analogs & derivatives. Arch Pharm Res. 2003 May;26(5):426-31
polyglyceryl-6-dioleate  0   *Oleic Acids Glycerol/*analogs & derivatives Polymers. Skin Pharmacol Appl Skin Physiol 2003 May-Jun;16(3):151-5
compritol HD5 ATO  0   *Polyethylene Glycols Glycerol/*analogs & derivatives. Int J Pharm. 2003 Mar 26;254(2):263-9
1-(11-selenadodecyl)-glycerol  0   Glycerol/*analogs & derivatives. Lipids 2002 Jul;37(7):633-40
1-(11-selenadodecyl)-3-trolox-glycerol  0   Glycerol/*analogs & derivatives. Lipids 2002 Jul;37(7):633-40
cardiobutanolide  0   Glycerol/*analogs & derivatives 4-Butyrolactone/*analogs & derivatives. Phytochemistry 2003 Feb;62(4):597-600
poly(glycerol-sebacate)  0   *Decanoates *Polymers Glycerol/*analogs & derivatives. Nat Biotechnol 2002 Jun;20(6):602-6
1-O-pentylglycerol  0   Glycerol/*analogs & derivatives. Cancer Chemother Pharmacol 2002 Oct;50(4):299-304
2-galactopyranosylglycerol  0   Glycerol/*analogs & derivatives Galactose. Carbohydr Res 2002 Feb 11;337(3):279-80
1-O-(9Z,12Z-octadecadienoyl)-3-O-nonadecanoyl glycerol  0   *Fatty Acids Glycerol/*analogs & derivatives. J Nat Prod 2002 Feb;65(2):206-9
1,2-di-O-(9Z,12Z,15Z-octadecatrienoyl)-3-O-(glucose(1-6)-allose)-glycerol  0   *Disaccharides Glycerol/*analogs & derivatives. Phytochemistry 2001 Dec;58(8):1305-9
1,2-di-O-(9,12,15-octadecatrienoyl)-3-O-(6-amine-6-deoxy-glucosyl)-glycerol  0   Glycerol/*analogs & derivatives Glycolipids. Phytochemistry 2001 Dec;58(8):1305-9
1-O-butanoyl-2-O-(6-O-butanoyl-glucopyranosyl)-glycerol  0   Glycerol/*analogs & derivatives. Eur J Med Chem 2001 Jul-Aug;36(7-8):691-5
glycerol 2-O-fucopyranoside  0   Glycerol/*analogs & derivatives. Phytochemistry 2001 Oct;58(4):641-4
1,2-dilinolenoyl-3-galactopyranosylglycerol  0   *Glucosides Glycerol/*analogs & derivatives. Phytochemistry 2000 Aug;54(8):867-70
1-(5'-methylfur-3'-yl)propane-1,2,3-triol  0   *Furans Glycerol/*analogs & derivatives. J Antimicrob Chemother 2000 Aug;46(2):181-9
glycero-gulo-heptose  0   *Heptoses Glycerol/*analogs & derivatives. Int J Mol Med 2000 Aug;6(2):171-5
1,2-diacyl-3-(galactopyranosyl)-sn-glycerol  0   *Monosaccharides Glycerol/*analogs & derivatives. Eur J Biochem 2000 Jun;267(12):3770-83
diacylglycerol pyrophosphate  0   *Diphosphates Glycerol/*analogs & derivatives. Ann N Y Acad Sci 2000 Apr;905
HD 166  0   *Glycerol *Succinic Acid. Int J Mol Med 2000 Jan;5(1):63-5
monobenzoyl glycerol  0   Glycerol/*analogs & derivatives. Bioorg Med Chem Lett 1999 Nov 15;9(22):3207-10
azido-LPC  0   *Glycerol *Phosphorylcholine Spin Labels. Biochim Biophys Acta 1999 Jul 9;1439(1):47-56
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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