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Solvents

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Definition: Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)  D25-26 qualif   
Examples Ionic Liquids
Substances having this pharmacologic action: 2-Propanol; 1-Octanol; cineole; Polyethylene Glycols; Chloroform; Ethanol; Methanol; Tetrachloroethylene; Turpentine; Toluene; 4-Butyrolactone; Triacetin; Trichloroethylene; Propylene Glycol; Glycerol; Dimethyl Sulfoxide; Acetone; Ether, Ethyl; Eugenol; 2-bromopropane
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
perfluoro-n-butyl iodide  0   *Butanes *Hydrocarbons, Fluorinated Solvents. Int J Toxicol. 2004 Jul-Aug;23(4):249-58
n-butylpropionate  590-01-2   *Propionates Solvents. J Toxicol Environ Health A 2000 Sep 29;61(2):79-105
testgasoline  0   *Hexanes *Pentanes Petroleum Solvents. J Urol 2000 Aug;164(2):451
O44, octane  0   *Hydrocarbons, Fluorinated *Octanes Solvents. Klin Monatsbl Augenheilkd 1999 Feb;214(2):71-6
PLAS-SD  0   Plasma Solvents. Aids Patient Care STDS 1998 Sep;12(9):667
2-ethylhexyl lactate  0   *Lactates Solvents. Regul Toxicol Pharmacol 1998 Apr;27(2):88-97
n-butyl lactate  138-22-7   *Lactates Solvents. Regul Toxicol Pharmacol 1998 Apr;27(2):88-97
1-octadecene  112-88-9   *Alkenes Solvents. Eur J Ophthalmol 1997 Jul-Sep;7(3):288-93
sodium ethoxide  141-52-6   Ethanol/*analogs & derivatives Solvents Tissue Embedding. Micron 1995;26(4):301-10
butyl decanoate  30673-36-0   *Decanoates Solvents Paraffin Embedding. Histochem Cell Biol 1995 Apr;103(4):263-9
tetralin  119-64-2   *Tetrahydronaphthalenes Solvents. Proc Natl Acad Sci U S A 1995 Aug 15;92(17):7617-21
Micro-Clear  158827-97-5 Micro-Clear  *Paraffin Solvents. J Clin Microbiol 1994 Aug;32(8):2028-30
tert-butyl acetate  540-88-5   *Acetates Solvents. Hum Exp Toxicol 1994 Jul;13(7);478-80
orange oil  8008-57-9   *Plant Oils Solvents. Braz Dent J 1993;4(1):43-7
decapex  0   Methylene Chloride/*analogs & derivatives Solvents. J Toxicol Clin Exp 1992 Oct-Nov;12(4-5):239-45
miglyol 840  77466-09-2   *Diglycerides Solvents. Exp Parasitol 1992 Dec;75(4):449-56
farbasol  0   *Benzene Derivatives Solvents. Med Pr 1992;43(2):129-35
ethyl propionate  105-37-3   *Propionates Solvents. Radiology 1991;180(1):47
isopropyl acetate  108-21-4   *Acetates Solvents. Radiology 1991;180(1):47
4-methylmorpholine N-oxide  7529-22-8   *Cyclic N-Oxides *Morpholines Solvents. Carbohydr Res 1990;206(1):167
ethyl 3-ethoxypropionate  763-69-9   *Propionates Solvents. Xenobiotica 1990;20(10):989
butyl diglycol acetate  124-17-4   *Ethylene Glycols Solvents. Contact Dermatitis 1989;21(1):52
octyl acetate  112-14-1   *Acetates Solvents. Fundam Appl Toxicol 1989;12(2):313
1,1-difluoroethane  75-37-6   *Hydrocarbons, Fluorinated Solvents. Vet Hum Toxicol 1989;31(1):65
N-isoamylphthalamide  41764-14-1   *Phthalic Acids Solvents. Gig Sanit 1987;(7):84
Hemo-De  106716-79-4 Hemo-De  *Terpenes Solvents. J Clin Microbiol 1987;25(2):425
basil oil  8015-73-4   *Plant Oils Solvents. Tsitologiia 1986;28(9):1030
tris(2-ethylhexyl)phosphate  78-42-2   *Phosphoric Acid Esters Solvents. Environ Health Perspect 1986;65:271
2-methoxy ethyl acetate  3938-96-3   *Acetates Solvents. Mutat Res 1986;174(1):11
methyl isoamyl ketone  110-12-3   *Hexanones Solvents. Fundam Appl Toxicol 1986;6(3):498
aromatol  88845-25-4   *Benzene Derivatives Solvents. Arch Toxicol [Suppl] 1985;8:442
methyl tert-butyl ether  1634-04-4   *Methyl Ethers Solvents.
Pharma Action Air Pollutants ; Carcinogens 		Gastroenterology 1985;88(1 Pt. 1):122
2,5-dimethylisosorbide  5306-85-4   Isosorbide/*analogs & derivatives Solvents. J Invest Dermatol 1984;82(1):49
isobutyl acetate  110-19-0   *Acetates Solvents. Acta Otolaryngol (Stockh) 1983;96(5-6):495
polymethionine sulfoxide  0   *Peptides Solvents. J Pharm Sci 1983;72(6):665
trioctylmethylammonium  5137-55-3   *Quaternary Ammonium Compounds Solvents. Bull Environ Contam Toxicol 1981;27(3):316; J Chromatogr 1983;257(2):305
triethylsulfonium  3378-18-5   *Sulfonium Compounds Solvents. Int J Environ Anal Chem 1983;13(2):141
isooctyl acid phosphate  12645-53-3 Phosphoric acid, isooctyl ester  *Phosphoric Acid Esters Solvents. Anal Chem 1981;53(14):2351
ethyl myristate  124-06-1   *Myristates Solvents. J Pharm Sci 1981;70(11):1225
ethyl pivalate  3938-95-2   *Valerates Solvents. J Pharm Sci 1981;70(11):1225
nitromors  0   *Methylene Chloride Solvents. Br Med J 1981;282(6281):2057
n-heptane  142-82-5   *Heptanes Solvents. Arch Environ Contam Toxicol 1980;9(6):661
4-tert-butyltoluene  98-51-1   Toluene/*analogs & derivatives Solvents. Acta Pharmacol Toxicol 1980;47(3):236
histosol  0   *Hydrocarbons Solvents. Anat Rec 1980;197(3):283
monooctanoin  26402-26-6 octanoic acid, monoester with 1,2,3-propanetriol  *Glycerides *Octanoic Acids Solvents. Gastroenterology 1980;78(5):1016; J Surg Res 26(4):378;1979MOCTANIN
glycerol formal  5464-28-8 1,3-dioxolane-4-methanol  *Dioxolanes Solvents. Acta Anat (Basel) 1980;106(2):203
1,1,1-trichloroethane  71-55-6 ethane, 1,1,1-trichloro  *Trichloroethanes Solvents. IARC Monogr Eval Carcinog Risk Chem Hum 1979;20:515
cremophor  39279-69-1   *Polyethylene Glycols Emulsions Solvents Pharmaceutical Vehicles. Br J Anaesth 51(9):891;1979
2-ethoxyethanol  110-80-5   *Ethylene Glycols Solvents. Stain Technol 54(3):111;1979
rubber solvent  0   *Hydrocarbons Solvents. Mutat Res 67(4):331;1979
tetrahydrofuran  109-99-9   *Furans Solvents. Biochim Biophys Acta 1980;617(1):97; Bull Environ Contam Toxicol 23(4-5):620;1979; Lung 155(4):297;1978; Sangyo Igaku 20(5):290;1978
phorone  504-20-1 2,6-dimethyl-2,5- heptadien-4-one  *Ketones Glutathione/antagonists & inhibitors Solvents. Toxicology 11(3):225;1978
glycofurol  9004-76-6 alpha-(tetrahydrofuranyl)-omega-hydroxypoly(oxy-1,2-ethanediyl)  *Polyethylene Glycols Solvents. Biochem Pharmacol 27(24):2851;1978
Extrelut  68445-07-8   *Diatomaceous Earth Solvents. J Chromatogr 161:360;1978
n-butoxyethanol  111-76-2   *Ethylene Glycols Ethers Solvents. Acta Pharm Tox 42(5):354;1978; Arch Biochem Biophys 1980;199(2):413; J Occup Med 20(10):675;1978
2-nitropropane  79-46-9   *Nitroparaffins Propane/*analogs & derivatives Solvents. Biochem J 175(2):601;1978; J Occup Med 20(5):333;1978; Vet Hum Toxicol 1979;21(Suppl):183
ligroin  8032-32-4   *Hydrocarbons Solvents. Scand J Work Environ Health 1(1):15-31;1976
Stoddard solvent  8052-41-3   *Hydrocarbons Petroleum Solvents. Am Ind Hyg Assoc J 36(7):553;1976
N-(2-hydroxyethyl)lactamide  5422-34-4 2-lactamidoethanol  *Amides Solvents. Stain Technol 51(2):115;1976
limonene  138-86-3   *Terpenes *Cyclohexenes Carcinogens Solvents Anticarcinogenic Agents. Digest Dis 21(11):926;1976; Food Cosmet Toxicol 12(5-6):703;1974; J Med Entomol 11(5):617;1974; Life Sci 19:1559;1976; Xenobiot 5(1):33;1975; Xenobiot 6(6):377;1976
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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