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Onium Compounds

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Definition: Ions with the suffix -onium, indicating cations with coordination number 4 of the type RxA+ which are analogous to QUATERNARY AMMONIUM COMPOUNDS (H4N+). Ions include phosphonium R4P+, oxonium R3O+, sulfonium R3S+, chloronium R2Cl+  DF: ONIUM CPDS   
Examples Quaternary Ammonium Compounds; Sulfonium Compounds
Other names Compounds, Onium
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-methoxyphenonium  0   *Onium Compounds. J Org Chem. 2011 Dec 2;76(23):9568-71
4-benzyloxyphenyl-(2-thienyl)iodonium bromide  0   *Onium Compounds *Thiophenes. Molecules. 2011;16(9) (dup#20):7621-6
2-methylphenyl(2'-methoxyphenyl)iodonium chloride  0   *Benzene Derivatives *Onium Compounds. Chemistry. 2010 Sep 10;16(34):10418-23
bis(pyridine)iodonium(I) tetrafluoroborate  0   *Onium Compounds *Pyridines. Biochemistry 2006 May 16;45(19):5957-63
2-(5-norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronim  0   *Cyclic N-Oxides *Onium Compounds. Protein Pept Lett 2006;13(2):189-92
phenyliodonium  0   *Onium Compounds. J Org Chem. 2005 Oct 28;70(22):8780-4
3-aminodiphenyleneiodium  0   *Onium Compounds. Cancer Sci 2003 Feb;94(2):148-52
phenoxaiodonium  0   *Onium Compounds. Eur J Pharmacol 2000 Aug 4;401(2);115-20
iodonium dicollidine  69417-67-0   *Onium Compounds *Pyridines. Carbohydr Res 1993 Mar 17;241:153-64
3,6-dimethylaminodibenzopyridonium edetate  143578-51-2 10H-Dibenz(b,e)iodinium, 3,7-bis(dimethylamino)-, salt with N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine) (1:1)  *Onium Compounds Edetic Acid/*analogs & derivatives. Yao Hsueh Hsueh Pao 1992;27(6):407-11
3,6-di-(dimethylamino)-dibenzopyriodonium lanthanum-EDTA  128480-86-4   *Onium Compounds *Organometallic Compounds Lanthanum. Sci China (B) 1989;32(8):918
3,6-di(dimethylamino)dibenzopyriodonium praseodymium dicitrate complex  120752-09-2   *Benzopyrenes *Onium Compounds *Organometallic Compounds Praseodymium. Chung Kuo Yao Li Hsueh Pao 1989;10(2):188
3,6-dimethylaminodibenzopyriodonium citrate  111950-71-1   *Onium Compounds. Chung Kuo Yao Li Hsueh Pao 1987;8(6):516
iodonium thiophene  45955-43-9   *Onium Compounds *Thiophenes. Biochem Pharmacol 1987;36(4):489
butyltriphenylphosphonium  22949-84-4   *Onium Compounds *Organophosphorus Compounds. Biochem J 1981;196(1):311
diphenyliodonium  10182-84-0   *Biphenyl Compounds *Onium Compounds.
Pharma Action Anti-Infective Agents
Microbios 1981;30(120):97
hydronium ion  13968-08-6 oxonium  *Onium Compounds. J Biol Chem 1980;255(23):11365
tetraphenylphosphonium  18198-39-5   *Onium Compounds *Organophosphorus Compounds.
Pharma Action Antineoplastic Agents ; Indicators and Reagents
Biochem Membr Transp FEBS Symp #42 W3F15#42:236;1976; Extreme Environ Mech Microb Adapt QW 52 E96:334;1974; J Biol Chem 254(20):10084;1979; J Membr Biol 49(2):105;1979; J Supramol Struct 6(1):125;1977; Proc Natl Acad Sci USA 1979;76(10):4783; Proc Natl Acad Sci USA 76(2):650;1979; Proc Natl Acad Sci USA 76(6):2580;1979
2,4-dichlorodiphenyleneiodonium  34563-73-0 bis(2,4-dichlorophenyl)iodonium chloride  *Onium Compounds. Biochem J 158(2):317;1976
triphenylmethylphosphonium  15912-74-0 methyltriphenylphosphonium  *Onium Compounds *Trityl Compounds.
Pharma Action Indicators and Reagents
Biochemistry 14(25):5451;1976; Biochemistry 16(12):2619;1977; Biochemistry 16(19):4328;1977; Biochemistry 17(22):4739;1978; Biochim Biophys Acta 440:557;1976; FEBS Lett 1979;108(1):274; J Bacteriol 126(2):706;1976; J Bacteriol 127(3):1255;1976; J Biol Chem 254(14):6703;1979; J Neurochem 1980;34(3):569; Proc Natl Acad Sci USA 74(6):2352;1977
trimethyloxonium  43625-65-6 Oxonium, trimethyl  *Onium Compounds. Biochem Biophys Res Commun 56(3):654;1974; Nature 1980;283(5744):293
diphenyleneiodonium  244-54-2 dibenziodolium  *Onium Compounds Nitric Oxide Synthase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors ; Hypoglycemic Agents
Biochem J 158(2):307-317;1976; Biochem J 163:605;1977; Biochem Soc Trans 3(2):333;1975; J Biol Chem 248(17):6050;1973; Xenobiotica 1979;9(9):539

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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