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Buffers

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Definition: A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer.  almost never IM   
Examples Ampholyte Mixtures 		Other names Ampholytes
Substances having this pharmacologic action: Tromethamine; HEPES; Bicarbonates; potassium phosphate; sodium citrate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
diphoterine  0   Organic Chemicals Buffers Ophthalmic Solutions. Burns 2002 Nov;28(7):670-3
LST buffer  0   *Polysorbates *Tromethamine Buffers Tissue Preservation. Am J Clin Pathol 1999 Jun;111(6):748-52
Tribonate  133249-32-8   *Bicarbonates *Tromethamine Buffers. Resuscitation 1994 Jul;28(1):27-36
TES-Tris yolk buffer  0   *Glucose *Tromethamine Buffers Egg Yolk Semen Preservation. Microsc Electron Biol Celular 1991 Jun;15(1):107-18
Tris-borate-EDTA buffer  0   *Boric Acids *Edetic Acid *Tromethamine Buffers. Biotechniques 991;10(2):182
3-thiomorpholinopropylacrylamide  131374-19-1   *Acrylamides *Morpholines Buffers. Electrophoresis 1990;11(8):617
2-thiomorpholinoethylacrylamide  131374-18-0   *Acrylamides *Morpholines Buffers. Electrophoresis 1990;11(8):617
N,N'-bis(2-hydroxyethyl)-N'-acryloyl-1,3-diaminopropane  131087-49-5   *Acrylates Buffers. J Biochem Biophys Methods 1990;21(2):165
Link  56560-67-9   *Aluminum Hydroxide *Carbonates Buffers Magnesium. Scand J Dent Res 1988;96(5):412
2-(N-cyclohexylamino)ethanesulfonic acid  103-47-9   Taurine/*analogs & derivatives Buffers. Proc Natl Acad Sci USA 1987;84(1):76
triethylammonium bicarbonate  15715-58-9   *Bicarbonates Buffers. Anal Biochem 1984;138(1):246
poly-N,N-dimethyl-N,N-diallylammonium chloride  26062-79-3 2-Propen-1-aminium, N,N-dimethyl-N-2-propenyl-, chloride, homopolymer  *Quaternary Ammonium Compounds *Polyethylenes Air Pollutants Buffers. Lab Delo 1984;(2):75
tris-boric-polyol buffer  0   *Boric Acids *Polymers *Tromethamine Drug Combinations Buffers. Lab Delo 1981;(4):232
calcium specific chelator  79735-36-7 Glycine, N-(2-((acetyloxy)methoxy)-2-oxoethyl)-N-(2-(2-(2-(bis(2-((acetyloxy)methoxy)-2-oxoethyl)amino)-5-methylphenoxy)ethoxy)phenyl)-, (acetyloxy)methyl ester  Glycine/*analogs & derivatives Buffers. Nature 1981;290(5806):527
Bistris  6976-37-0   Tromethamine/*analogs & derivatives Buffers. Eur J Biochem 1980;107(2):455
N-(2-acetamido)-2-aminoethanesulfonic acid  7365-82-4 Ethanesulfonic acid, 2-((2-amino-2-oxoethyl)amino)  Taurine/*analogs & derivatives Buffers. Anal Biochem 1980;103(2):214
2-amino-2-methyl-1,3-propandiol  115-69-5   *Propylene Glycols Buffers. Enzyme 24(1):18;1979
BES  10191-18-1 N,N-bis(2-hydroxyethyl)aminoethanesulfonic acid  *Alkanesulfonic Acids Buffers. Anal Chem 48(9):1293;1976
3,3-dimethylglutarate  4839-46-7   *Glutarates Buffers. Am J Physiol 229(3):831;1975
1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol  102-60-3   *Ethylenediamines Buffers. Biochemistry 14(13):3029;1975; Environ Lett 8(4):345;1975
piperazine-N,N'-bis(2-ethanesulfonic acid)  5625-37-6   *Piperazines *Alkanesulfonic Acids Buffers. Eur J Biochem 1980;103(1):47; J Biol Chem 249(7):2005;1974
morpholinopropane sulfonic acid  1132-61-2   *Morpholines Buffers. Arch Biochem Biophys 183(1):317;1977; Arch Microbiol 115:169;1977; Cancer Res 34(11):2957;1974
2-amino-2-methyl-1-propanol  124-68-5   *Propanolamines Buffers. Clin Chem 23(2):200;1977; Clin Chem 24(9):1611;1978; Clin Chim Acta l979;98(1-2):61
sulfamic acid  5329-14-6   *Sulfonic Acids Buffers Flame Retardants.
Pharma Action Herbicides ; Indicators and Reagents 		Aichi-Gakuin J Dental Sci 13(3):318;1975; Am Ind Hyg Assoc J 36(3):181;1975; Eisei Shikenjo Hokoku 92:89;1974; Fd Cosmet Toxicol 14(1):81;1976; Food Cosmet Toxicol 16(4):365;1978; J Dent 6(3):222;1978; J Med Chem 19(7):869;1976; Toxicology 1979;13(1):45; Z Med Lab Diagn 20(1):38;1979
TES  7365-44-8 N-tris(hydroxymethyl)methyl-2-aminomethane sulfonate  Tromethamine/*analogs & derivatives Buffers. Aust J Biol Sci 25(5):1047;1973
2-(N-morpholino)ethanesulfonic acid  4432-31-9   *Morpholines *Alkanesulfonic Acids Buffers. Anal Chem 48(9):1293;1976; Arch Biochem Biophys 1979;197(2):470; Arch Microbiol 115:169;1977; Aust J Biol Sci 25(5):1047;1973; Biochim Biophys Acta 518:535;1978
Ampholine  37348-94-0   *Polymers Polyamines Buffers Isoelectric Focusing. Anal Biochem 70(2):542;1976; Anal Biochem 71(2):325;1976; Australian J Exp Biol Med Sci 56(2):169;1978; Biochim Biophys Acta 542(2):232;1978; Cell Immunol 34:340;1977; Folia Haematol 102(4):454;1975; Science Tools 14(2):17;1967
caprogen  0   *Caproates Buffers.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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