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Propanolamines

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Definition: AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.     
Examples Acebutolol; Alprenolol; Atenolol; Betaxolol; Bisoprolol; Bupranolol; Carteolol; Celiprolol; Ephedrine; Histidinol; Isoxsuprine; Levobunolol; Methoxamine; Metipranolol; Metoprolol; Nadolol; Nylidrin; Oxprenolol; Oxyfedrine; Penbutolol; Phenoxypropanolamines; Phenylpropanolamine; Pindolol; Practolol; Prenalterol; Propranolol; Pseudoephedrine; Ritodrine; Suloctidil; Timolol; Xamoterol
Other names Aminopropanols
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
JTT 305  0   *Propanolamines *Benzoic Acids. Clin Calcium. 2011 Jan;21(1):89-93.
2-amino-N-(1-(2-amino-3-(4-aminophenyl)-3-hydroxypropylamino)-1-oxo-3-phenylpropan-2-yl)-4-methylpentanamide  0   *Dipeptides *Propanolamines Antigens, CD13/antagonists & inhibitors. Bioorg Med Chem. 2011 Sep 1;19(17):5190-8.
(S)-2-amino-1-propanol  0   *Propanolamines. J Am Chem Soc. 2011 May 11;133(18):6968-77
2-N-(16-(1'-pyridinium)hexadecanoylamino)-1-(4'-nitrophenyl)-1,3-propandiol  0   *Propanolamines *Pyridinium Compounds. Bioorg Med Chem 2008 Jan 15;16(2):1015-31
1-(4-nitrophenyl)-2-(methionylsulfonamido)-1,3-propadiol  0   *Propanolamines Methionine/*analogs & derivatives. Bioorg Med Chem 2010 Nov 15;18(22):7868-72
2-amino-2-(2-(2'-fluoro-4'-(4-methylphenylthio)biphenyl-4-yl)ethyl)propane-1,3-diol  0   *Biphenyl Compounds *Propanolamines Receptors, Lysosphingolipid/agonists. J Med Chem 2010 Apr 22;53(8):3154-68
3-(3-cyano-4-((3-((1,1-dimethyl-2-(2-naphthalenyl)ethyl)amino)-2-hydroxypropyl)oxy)phenyl)propanoic Acid  0   *Phenylpropionates *Propanolamines Receptors, Calcium-Sensing/antagonists & inhibitors. J Med Chem 2009 Nov 12;52(21):6599-605
An-2 compound  0   *Propanolamines Lactose/*analogs & derivatives Antigens, CD11b. Glycocong J 2009 Feb;26(2):173-88
2-N-(tetradecylamino)-1-phenyl-1,3-propanediol  0   *Myristates *Propanolamines. Bioorg Med Chem 2008 Jan 15;16(2):1015-31
1-(1-fluoropropan-2-ylamino)-3-(2-cyclohexylphenoxy)propan-2-ol  0   *Propanolamines Fluorine Radioisotopes. Neurochem Int 2008 Nov;53(3):173-9
1-(isopropylamino)-3-(5-((isopropylamino)methyl)-2-methoxyphenoxy)propan-2-ol  0   *Benzylamines *Propanolamines. J Pharm Pharmacol 2008 Nov;60(11):1501-6
3-(methylamino)-2-(naphthalen-2-yl)-1-phenylpropan-1-ol  0   *Naphthalenes *Propanolamines. J Pharmacol Exp Ther 2008 Nov;327(2):573-83
1-(1-fluoropropan-2-ylamino)-3-(3-tolyloxy)propan-2-ol  0   *Propanolamines Fluorine Radioisotopes. J Med Chem 2008 Aug 28;51(16):5093-100
1-(tert-butylamino)-3-(5-tert-butylaminomethyl-2-methoxyphenoxy)propan-2-ol  0   *Benzylamines *Propanolamines Receptors, Adrenergic, beta. J Pharm Pharmacol 2007 Mar;59(3):429-36
2-(3-azido-4-octylphenethyl)-2-aminopropane-1,3-diol  0   *Azides *Propanolamines. J Org Chem 2006 Mar 3;71(5):2200-2
oxypropanolamine  0   *Propanolamines. Arch Pharm Res. 2005 Dec;28(12):1317-23
wiskostatin  0   *Carbazoles *Propanolamines. Nat Struct Mol Biol 2004 aug;11(8):747-55
2-I-ICI-H  0   *Biphenyl Compounds *Propanolamines. Nuklearmedizin. 2003 Aug;42(4):173-80
3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol  0   *Aniline Compounds *Propanolamines. J Med Chem 2003 May 22;46(11):2152-68
KMUP 880602  0   *Propanolamines Vanillic Acid/*analogs & derivatives. J Cardiovasc Pharmacol 2002 Jun;39(6):803-13
fluoroethylcarazolol  0   *Carbazoles *Propanolamines. Neurochem Int 2002 Jul;41(1):17-27
esprolol  0   *Propanolamines. Heart Dis 2000 Mar-April;2(2):146-50
2-N-myristoylamino-1-(4-nitrophenyl)-1,3-propandiol  0   *Myristates *Propanolamines. FEBS Lett 2002 Apr 10;516(1-3):47-52
iosmin  0   *Benzamides *Propanolamines. Invest Radiol 2002 Jan;37(1):29-34
SC 795  0   *Propanolamines. J Med Chem 2000 Nov 30;43(24):4575-8
N-(1-(4-nitrophenyl)-1,3-dihydroxyprop-2-yl)tetradecanamide  0   *Amides *Propanolamines. Cancer Res 2001 Feb 1;61(3):1233-40
AMPD 4  0   *Propylene Glycols *Propanolamines. Bioorg Med Chem Lett 2000 Feb 21;10(4):337-9
HCL 31D  0   *Propanolamines *Pyridazines. Eur J Pharmacol 2000 Jan 10;387(2):125-31
4'-hydroxy-1-phenyl-2-palmitoylaminio-3-pyrrolidino-1-propanol  0   *Propanolamines *Pyrrolidines. Kidney Int 2000 Feb;57(2):446-54
3',4'-ethylenedioxyphenyl-2-palmitoylamino-3-pyrrolidino-1-propanol  0   *Propanolamines *Pyrrolidines. Kidney Int 2000 Feb;57(2):446-54
N-palmitoylserinol  0   *Palmitic Acids *Propanolamines Apoptosis. J Biol Chem 2000 Jan 7;275(1):177-81
N-stearylserinol  0   *Propanolamines *Stearic Acids Apoptosis. J Biol Chem 2000 Jan 7;275(1):177-81
hydroxyphenylpropanolamine  0   *Propanolamines. Chirality 1999 ;11(9):684-8
1-phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol  0   *Propanolamines *Pyrrolidines. Methods Enzymol 2000;311:373-87
H 224-45  0   *Amides *Propanolamines. J Med Chem 1998 Dec 31;41(27):5282-92
H 95-71  0   *Formamides *Propanolamines. J Med Chem 1998 Dec 31;41(27):5382-92
beta-cyclodextrin-2-hydroxy-3-trimethylammoniumpropyl ether chloride  0   *Propanolamines *beta-Cyclodextrins. Electrophoresis 1998 May;19(5):738-44
N,N'-(2-hydroxy-1,3-propanediyl)-bis(2-iodoacetamide)  0   *Acetamides *Propanolamines. FEBS Lett 1998 May 15;427(3):362-6
2-(2-hydroxy-3-isoprpylaminopropoxy)-5-(propoxymethy)acetophenone  0   *Acetophenones *Propanolamines. Ceska Slov Farm 1997 Oct;46(5):230-4
1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol  0   *Propanolamines *Pyrrolidines. J Neurochem 1998 Feb;70(2):467-72
3-amino-1-propanol  156-87-6   *Propanolamines. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1997 Sep;118(1):83-7
BM 910228  0   *Carbazoles *Propanolamines. Free Radic Biol Med 1996;21(6):813-25
bufetolol  53684-49-4   *Propanolamines.
Pharma Action Adrenergic beta-Antagonists
Br Med J [Clin Res] 1982;285(6341):543
tolamolol  38103-61-6   *Propanolamines. Int J Clin Pharmacol Res 1983;3(6):459
Ko 1313  38555-07-6   *Propanolamines.
2-(N-myristoylamino)-1-phenyl-1-propanol  60847-25-8   *Myristates *Propanolamines. J Biol Chem 1996 May 24;271(21):12646-54
1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol  127003-40-1   *Propanolamines. Thromb Res 1996 Jan 1;81(1):43-54
dridocainide  0   *Benzylidene Compounds *Propanolamines. Naunyn Schiedebergs Arch Pharmacol 1995 Nov;352(5):520-8
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate  0   *Propanolamines.
Pharma Action Adrenergic beta-3 Receptor Antagonists
Mol Pharmacol 1996 Jan;49(1):7-14
GR 81706  0   *Propanolamines *Pyridines. Br J Pharmacol 1994 Dec;113(4):1311-6
dextran-(1,6-bis(2-hydroxypropyl-1-amino)hexane)-dextran  0   *Dextrans *Propanolamines. J Biomater Sci Polym Ed 1994;6(6):549-64
1-acetamino-3-(1-naphthyloxy)-2-propanol  0   *Acetamides *Propanolamines. Biol Pharm Bull 1994 Nov;17(10):1433-5
5'-O-(((2-decanoyl-amino-3-hydroxy-3-phenylpropyloxycarbonyl)amino)sulfonyl)-2',3'-O-isopropylideneuridine  149992-49-4   *Propanolamines Uridine/*analogs & derivatives Glucuronosyltransferase/antagonists & inhibitors. Biochim Biophys Acta 1995 Jan 18;1243(1):9-14
dehydrozingeronolol  158102-53-5 3-Buten-2-one, 4-(04-(02-hydroxy-3-0(1-methylethyl)amino)propoxy)-3-methoxyphenyl  *Butanones *Propanolamines. Gen Pharmacol 1994 Jul;25(4):651-9
fluorocarazolol  157989-11-2   *Carbazoles *Propanolamines Fluorine Radioisotopes. J Med Chem 1994 Sep 30;37(20):3219-30
SB 209995  146574-41-6   *Carbazoles *Propanolamines. Pharmacology 1994 Jun;48(6):385-91
vaninolol  0   *Butanones *Propanolamines. Biochem Pharmacol 1994 Jul 5;48(1):101-9
SB 211475  146574-43-8   *Carbazoles *Propanolamines. Eur J Pharmacol 1994 Jan 14;251(2-3):237-43
CGP 55845A  148056-42-2   *Phosphinic Acids *Propanolamines.
Pharma Action GABA Antagonists
Neuron 1993 Dec;11(6):1057-67
bunitrolol  34915-68-9 Benzonitrile, 2-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)  *Propanolamines.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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