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Ephedrine

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Definition: A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.     
Pharmacological Action Adrenergic Agents; Central Nervous System Stimulants; Sympathomimetics; Vasoconstrictor Agents 		Other names Sulfate, Ephedrine; SalPhedrine; Sal Phedrine; Renaudin, Ephedrine; Hydrochloride, Ephedrine; Ephedrine Erythro Isomer; Wendt Brand of Ephedrine Sulfate; Sal-Phedrine; Renaudin Brand of Ephedrine Hydrochloride; Erythro Isomer of Ephedrine; Ephedrine Sulfate; Ephedrine Renaudin; Ephedrine HydrochlorideDrugs* : NOVAFED; SUDAFED 12 HOUR; PSEUDO-12; PSEUDOEPHEDRINE HYDROCHLORIDE; SUDAFED 24 HOUR; AFRINOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(1R,2S)-(-)-N-dodecyl-N-methylephedrinium bromide  0   Ephedrine/*analogs & derivatives. J Colloid Interface Sci. 2005 Dec 1;292(1):255-64
chloroephedrine  0   Ephedrine/*analogs & derivatives. J Anal Toxicol 2000 Oct;24(7):602-5
polyoxyethylene bis(ephedrine)  0   *Polyethylene Glycols Ephedrine/*analogs & derivatives. Anal Chem 1997 Jul 15;69(14):2734-41
2-(4-methoxyphenyl)-3,4-dimethyl-5-phenyloxazolidine  0   Ephedrine/*analogs & derivatives. Rapid Commun Mass Spectrom 1997;11(6):598-602
ma-huang (plant extract)  0   *Plant Preparations Drugs, Chinese Herbal Ephedrine. Am J Gastroenterol 1996 Jul;91(7):1436-8
dixaphen  0   *Benzamides *Caffeine *Ephedrine Drug Combinations. Vopr Onkol 1992;38(2):148-53
vicedrin  0   *Ascorbic Acid *Ephedrine *Phenacetin Drug Combinations. Cesk Pediatr 1991;46(2):98
3-hydroxyephedrine  3002-40-2   Ephedrine/*analogs & derivatives Carbon Radioisotopes.
Pharma Action Contrast Media 		J Nucl Med 1990;31(8):1328
caffeine, chlorpheniramine, dihydrocodeine, methylephedrine drug combination  0   *Caffeine *Chlorpheniramine Codeine/*analogs & derivatives Drug Combinations Ephedrine/*analogs & derivatives. Arukoru Kenyuto Yakubutsu Ison 1989;24(5):417
15-cyclopentyl-7-oxo-prostaglandin I2-ephedrine  100992-40-3   Ephedrine/*analogs & derivatives Epoprostenol/*analogs & derivatives. Thromb Res 1987;47(1):117
7-oxo-prostaglandin I2-ephedrine  108590-75-6   Ephedrine/*analogs & derivatives Epoprostenol/*analogs & derivatives. Thromb Res 1987;47(1):117
N-methylephedrine  17605-71-9   Ephedrine/*analogs & derivatives. Eisei Shikenjo Hokoku 1983;(101):1
ephedrine, proxyphylline drug combination  0   *Ephedrine Aminophylline/*analogs & derivatives Drug Combinations. ZFA (Stuttgart) 1983;59(30):1703
asmoganglina  0   *Ephedrine *Tissue Extracts Drug Combinations. Acta Med Leg Soc (Liege) 1982;32:271
cinnamedrine  90-86-8   Ephedrine/*analogs & derivatives. Arch Intern Med 1982;142(8):1583
Midol  83514-22-1 Benzoic acid, 2-(acetyloxy)-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, N-(4-ethoxyphenyl)acetamide and alpha-(1-(methyl(3-phenyl-2-propenyl)amino)ethyl)benzenemethanol hydrochloride  *Aspirin *Caffeine *Phenacetin Drug Combinations Ephedrine/*analogs & derivatives. Arch Intern Med 1982;142(8):1583MIDOL
caffeine, ephedrine drug combination  0 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-, mixt. with (R-(R*,S*))-alpha-(1-(methylamino)ethyl)benzenemethanol  *Caffeine *Ephedrine Drug Combinations. Int J Obes 1981;5(2):183
oxilofrine  52671-39-3 Benzenemethanol, 4-hydroxy-alpha-(1-(methylamino)ethyl)  Ephedrine/*analogs & derivatives. Arzneim Forsch 1980;30(5):776; Arzneim Forsch 25(5):742;1975; C R Soc Biol(Paris) 168:1230:1974; Mater Med Pol 7(4):261;1975
Quadrinal  78515-92-1 Benzoic acid, 2-hydroxy-, calcium salt (2:1), compd. with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1), mixt. with 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione, (R-(R*,S*))-alpha-(1-(methylamino)ethyl)benzenemethanol hydrochloride and potassiu  *Ephedrine *Iodides *Phenobarbital *Salicylates *Theophylline Drug Combinations. South Dakota J Med 31(10):16;1978
ephedrine phosphate  55340-64-2   Ephedrine/*analogs & derivatives. Cancer Treat Rep 61(2):259;1977; Histochemistry 56:133;1978
N-desmethylephedrine phosphate  63620-43-9 Benzenemethanol, alpha-(1-aminoethyl)-, dihydrogen phosphate (ester)  Ephedrine/*analogs & derivatives. Cancer Treat Rep 61(2):259;1977
colchiceineamide-L-ephedrine phosphate  76109-92-7 Benzo(a)heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-7-(methyl(1-methyl-2-phenyl-2-(phosphonooxy)ethyl)amino)-, disodium salt, (7S-(7R*(1R*,2S*)))  Colchicine/*analogs & derivatives Ephedrine/*analogs & derivatives. Cancer Treat Rep 61(2):259;1977
efatin  53988-96-8   *Atropine *Ephedrine *Procaine Drug Combinations. Farm Zh 29(5):69;1975; Farm Zh 4:67;1976; Ter Arkh 50(3):20;1978
Tedral  8057-98-5   *Ephedrine *Phenobarbital *Theophylline Drug Combinations. Ann Allergy 1979;43(6):348; Therapeutique 49(9):591;1974
1-phenoxy-2-(N-methylpiperazino)-3-ephedrinopropane hydrochloride  53283-77-5   Ephedrine/*analogs & derivatives. Indian J Exp Biol 12(2):138;1974
nethaprin dospan  8056-81-3 Nethaprin dospan  *Phenylephrine Doxylamine/*analogs & derivatives Drug Combinations Ephedrine/*analogs & derivatives Theophylline/*analogs & derivatives. Curr Med Res Opin 2(4):222;1974; Curr Med Res Opin 4(6):436;1976; Minerva Med 67(16):1005;1976
etafedrine  7681-79-0 alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol  Ephedrine/*analogs & derivatives. Arzneim Forsch 27(4):883;1977
H 35-25  13549-60-5 benzenemethanol, 4-methyl-alpha-(1-((1-methylethyl)amino)ethyl)  Ephedrine/*analogs & derivatives. Acta Physiol Scand 102:459;1978; Acta Physiol Scand 97(1):88;1976; Br J Pharmacol 59(1):135;1977; Clin Sci Mol Med 48(Suppl 2):89;1975; Eur J Pharmacol 37(1):91;1976; J Pharm Pharmacol 29(3):184;1977; Res Vet Sci 1979;27(3):372
Pasuma (tablet)  0   *Caffeine *Ephedrine *Methyltestosterone *Vitamin E *Yohimbine Drug Combinations Strychnine/*analogs & derivatives. S Afr Med J 53(18):693;1978
Sulfa-Dysurgal  0   *Atropine *Barbital *Ephedrine *Orotic Acid *Sulfanilamides Drug Combinations.
Novipec  0   *Anilides *Ephedrine *Oils, Volatile Drug Combinations.
chlorpheniramine, ephedrine drug combination  0   *Chlorpheniramine *Ephedrine Drug Combinations.
Pharma Action Histamine H1 Antagonists ; Sympathomimetics 		S Afr Med J 46(19):579;1972
franol  8058-86-4   *Ephedrine *Ethylenediamines *Phenobarbital *Theophylline Drug Combinations Asthma/drug therapy.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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