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Asthma

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Definition: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).  note specifics; ASTHMA, CARDIAC see DYSPNEA, PAROXYSMAL is also available; in historical literature consider indexing "phthisic" here; "phthisis" probably goes under TUBERCULOSIS, PULMONARY   
See Also Anti-Asthmatic Agents
Examples Asthma, Aspirin-Induced; Asthma, Exercise-Induced; Asthma, Occupational; Status Asthmaticus
Other names Bronchial Asthma; Asthma, Bronchial; Asthmas
 
SubstanceCAS Registry & nameCategoriesSource
ASHMI herbal formula  0   *Drugs, Chinese Herbal Asthma/drug therapy. Clin Exp Allergy. 2010 Nov;40(11):1678-88
EFF1009  0   *Eicosapentaenoic Acid *gamma-Linolenic Acid Asthma/diet therapy Food, Fortified. Curr Med Res Opin. 2009 Dec;25(12):2865-75
wuwei dilong  0   *Drugs, Chinese Herbal Asthma/drug therapy. J Tradit Chin Med. 2009 Sep;29(3):220-3
LELP1 protein, human  0   *Cornified Envelope Proline-Rich Proteins Asthma. J Hum Genet. 2007;52(4):378-83
fenspiride  5053-06-5 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(2-phenylethyl)  *Spiro Compounds Asthma Anti-Asthmatic Agents.
Pharma Action Bronchodilator Agents
ambophyllin  0   *Triamcinolone Asthma. J Allergy Clin Immunol 1992 Jul;90(1):127-9
2-ethoxyethyl N-(4-(3-methyl-5-isoxazolyl)-2-thiazolyl)oxamate  104777-03-9   *Isoxazoles Oxamic Acid/*analogs & derivatives Asthma/drug therapy. J Med Chem 1991;34(2):600
3-(5-hydroxy-4,6,7-trimethyl-1,3-benzoxathiazol-2-yl)propanol  100480-81-7   *Benzoxazoles Arachidonate 5-Lipoxygenase/antagonists & inhibitors Asthma/drug therapy. J Med Chem 1990;33(5):1491
5-hydroxy-4,6,7-trimethyl-2-propyl-1,3-benzoxathiazole  100480-17-9   *Benzoxazoles Asthma/drug therapy. J Med Chem 1990;335):1491
aminophylline, cycloclenbutrerol, diphenydramine, phenobarbital drug combination  0   *Aminophylline *Diphenhydramine *Phenobarbital Clenbuterol/*analogs & derivatives Drug Combinations Asthma/drug therapy. Chung Hua Chieh Ho Ho Hu Hsi Hsi Chi Ping Tsa Chih 1982;4(6):333
nivimedone  49561-92-4 1H-indene-1,3(2H)-dione, 5,6-dimethyl-2-nitro  *Indans Asthma/drug therapy. Agents Actions 8(3):199;1978; Br J Dis Chest 72(3):225;1978; Clin Allergy 1979;9(4):373; Clin Allergy 6:463;1976; Clin Allergy 6:471;1976; Int Arch Allergy Appl Immunol 51(2):226;1976; Int Arch Allergy Appl Immunol 60(2):216;1979; Lancet 1(8075):1200;1978; Lancet 1(8078):1365;1978
doxantrazole  51762-95-9   *Thioxanthenes Xanthones Asthma/drug therapy Hypersensitivity/drug therapy.
Pharma Action Bronchodilator Agents ; Phosphodiesterase Inhibitors
Acta Allergolog 31:471;1976; Annals Allergy 40(1):25;1978; Br J Pharm 59(3):473P;1977; Br Med J 1(6156):92;1979; Br Med J 3(5978):283;1975; Eur J Clin Pharm 11(2):107;1977; Int Arch Allerg Appl Immunol 56:39;1978; Int Arch Allergy Appl Immunol 1980;61(1):75; J Chromatogr 115(1):93;1975; J Invest Dermatol 71(4):266;1978; J Membrane Biol 39:57;1978; J Pharm Pharmacol 1979;31(11):730; J Pharmkinet Biopharm 6(6):521;1978; Lancet 1(7917):1169;1975; Lancet 1(8015):809;1977; Life Sci 18(2):153;1976; Tubercle 56(2):172;1975
arpenal  298-60-2   *Diphenylacetic Acids Asthma/drug therapy. Eksp Med Morfol (Sofia) 15(4):237;1976; Farmakol Toksikol 38(2):141;1975; Farmakol Toksikol 38(3):294;1975
4-oxo-4H-(1)benzofuro(3,2-b)pyran-2-carboxylic acid  42373-13-7   *Pyrans Asthma/drug therapy. J Med Chem 16(7):861;1973
4-oxo-4H-(1)benzothieno(3,2-b)pyran-2-carboxylic acid  40040-62-8   *Pyrans Asthma/drug therapy. J Med Chem 16(7):861;1973
Histaglobin  37317-09-2 1H-Imidazole-4-ethanamine, dihydrochloride, mixt. with gamma-globulins  *gamma-Globulins *Histamine Drug Combinations Asthma/drug therapy. Fiziol Ah 22(3):357;1976; Pediatr Akush Ginekol 1:18;1977; Probl Tuberk 2:47;1976; Srp Arh Celok Lek 1979;107(5):477; Vestn Otorinolaringol 3:26;1979; Z Erkr Atmungsorgane 136(3):337;1972
Germakhellin  77416-69-4 10H-Phenothiazine-10-ethanaminium, N,N,N,alpha-tetramethyl-, methyl sulfate, mixt. with 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6-dione and 4,9-dimethoxy-7-methyl-3-(1-piperazinylmethyl)-5H-furo(3,2-g)(1)benzopyran-5-one  Drug Combinations Dyphylline/*analogs & derivatives Khellin/*analogs & derivatives Promethazine/*analogs & derivatives Asthma/drug therapy.
franol  8058-86-4   *Ephedrine *Ethylenediamines *Phenobarbital *Theophylline Drug Combinations Asthma/drug therapy.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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