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Ascorbic Acid

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Definition: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.  /defic   
Pharmacological Action Vitamins; Antioxidants
Examples Dehydroascorbic Acid 		Other names Vitamin C; L Ascorbic Acid; Ascorbate, Sodium; Ascorbate, Ferrous; Acid, L-Ascorbic; Acid, Ascorbic; Sodium Ascorbate; Magnorbin; Magnesium Ascorbicum; L-Ascorbic Acid; Hybrin; Ferrous Ascorbate; Ascorbic Acid, Monosodium SaltDrugs* : MOVIPREP; ASCORBIC ACID; POLYETHYLENE GLYCOL 3350; POTASSIUM CHLORIDE; SODIUM ASCORBATE; SODIUM CHLORIDE; SODIUM SULFATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ocuvite plus lutein  0   *Ascorbic Acid *Niacin *Riboflavin *Vitamin E *Lutein *beta Carotene Dietary Supplements. Exp Eye Res. 2007 Apr;84(4):718-28.
ascorbyl-succinic-saquinavir  0   Ascorbic Acid/*analogs & derivatives Saquinavir/*analogs & derivatives. Int J Pharm. 2011 Jul 29;414(1-2):77-85.
Magne B6  0   *Ascorbic Acid *Magnesium *Vitamin B 6 Dietary Supplements. Zh Nevrol Psikhiatr Im S S Korsakova. 2011;111(5):56-9
RB Tone forte  0   *Zinc *Folic Acid Ascorbic Acid/*analogs & derivatives Drug Combinations Anemia, Iron-Deficiency/drug therapy. Indian Med Assoc. 2011 Feb;109(2):121-3
erythroascorbate glucoside  0   *Glucosides Ascorbic Acid/*analogs & derivatives. J Agric Food Chem 2010 Oct 13;58(19):10631-8
5'-O-glucopyranosyldihydroascorbigen  0   *Glucosides Ascorbic Acid/*analogs & derivatives. Carbohydr Res 2010 Sep 3;345(13):1968-70
Viusid  0   *Zinc *Ascorbic Acid *Glycyrrhizic Acid Hepatitis C, Chronic/drug therapy. World J Gastroenterol. 2010 Jun 7;16(21):2638-47
ascorbylperoxide  0   *Peroxides Ascorbic Acid/*analogs & derivatives. J Pharmacol Exp Ther 2010 Jul;334(1):278-84
ascorbyl 2,6-dipalmitate  0   *Ascorbic Acid *Palmitates. Int J Pharm. 2010 Mar 15;387(1-2)
6-ascorbate-polyethylene glycol-1,2-stearoyl-glycero-3-phosphoethanolamine  0   *Phosphatidylethanolamines Ascorbic Acid/*analogs & derivatives. Bioconjug Chem 2009 Dec;20(12):2348-55
6-palmitoyl ascorbic acid-2-glucoside  0   *Glucosides Ascorbic Acid/*analogs & derivatives. J Radiat Res (Tokyo). 2009 May;50(3):203-12
5,6-isopropylidene ascorbate  0   Ascorbic Acid/*analogs & derivatives. J Am Chem Soc. 2008 Jun 18;130(24):7546-7
disodium isostearyl 2-O-L-ascorbyl phosphate  0   Ascorbic Acid/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2008 Mar;56(3):292-7
5,6-O-isopropylidene-2-O-allylascorbic acid  0   *Allyl Compounds Ascorbic Acid/*analogs & derivatives. J Inorg Biochem 2008 Feb;102(2):251-9
pQ510 compound  0   *Ascorbic Acid *Organometallic Compounds Titanium. Bull Exp Biol Med 2007 Jun;143(6):678-81
5-O-(4'-iodobenzyl)-L-ascorbic acid  0   Ascorbic Acid/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2007 Dec;55(12):1700-3
HUM 5007  0   *Cholecalciferol *Ascorbic Acid *Nicotinic Acids *Plant Extracts Dehydroepiandrosterone/*analogs & derivatives. J Nutr Biochem 2007 Sep;18(9):629-34
1-(6-(4-bromophenyl)furo(2,3-d)pyrimidin-2-on-3-yl)-2-(2',3'-di-O-benzyl-2'-buten-4'-olidylidene)ethane  0   *Pyrimidinones Ascorbic Acid/*analogs & derivatives. J Med Chem 2007 Aug 23;50(17):4105-12
1-(6-butylfuro(2,3-d)pyrimidin-2-on-3-yl)-2-(2',3'-di-O-benzyl-2'-buten-4'-olidylidene)ethane  0   *Pyrimidinones Ascorbic Acid/*analogs & derivatives. J Med Chem 2007 Aug 23;50(17):4105-12
ascorbyl lactate  0   *Lactates Ascorbic Acid/*analogs & derivatives. Appl Biochem Biotechnol 2007 Feb;136(2):153-64
1,12-diascorbyl dodecanedioate  0   Ascorbic Acid/*analogs & derivatives. J Am Chem Soc. 2006 Jun 7;128(22):7209-14
tetra-isopalmitoyl ascorbic acid  0   *Glycolipids Ascorbic Acid/*analogs & derivatives. J Dermatol Sci 2006 Oct;44(1):37-44
ascovertin  0   *Ascorbic Acid Quercetin/*analogs & derivatives. Bull Exp Biol Med 2005 Nov;140(5):578-81
S(2) complex  0   *Ascorbic Acid *Copper *Niacinamide. Exp Parasitol 2006 Feb;112(2):85-91
ascorbyl 4-hydroxy-2-nonenal  0   *Aldehydes Ascorbic Acid/*analogs & derivatives. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Nov 15;827(1):139-45
retinyl ascorbate  0   *Retinoids Ascorbic Acid/*analogs & derivatives. Free Radic Res 2005 May;39(5):491-8
ascorbyl linoleate  0   *Linoleic Acids Ascorbic Acid/*analogs & derivatives. Biotechnol Lett 2004 Dec;26(23):1777-80
ascorbyl oleate  0   *Oleic Acids Ascorbic Acid/*analogs & derivatives. Biotechnol Lett 2004 Dec;26(23):1777-80
2-O-(beta-D-glucopyranosyl)ascorbic acid  0   Ascorbic Acid/*analogs & derivatives. J Agric Food Chem. 2004 Apr 7;52(7):2084-91
karinat  0   *Ascorbic Acid *beta Carotene *alpha-Tocopherol Garlic. Vopr Onkol 2004;50(1):81-5
MAGIC polymer gel  0   *Ascorbic Acid *Gelatin *Hydroquinones *Methacrylates *Polymers *Copper Sulfate. Phys Med Biol 2002 Dec 21;47(24):4397-409
octanoyl-6-O-ascorbic acid  0   Ascorbic Acid/*analogs & derivatives. J Pharm Sci 2002 Aug;91(8):1810-6
6-acyl-ascorbic acid-2-glucoside  0   Ascorbic Acid/*analogs & derivatives Free Radical Scavengers. Chem Pharm Bull (Tokyo) 2001 May;49(5):642-4
green tea bioflavonoid, zinc ascorbate-containing toothpaste  0   *Ascorbic Acid *Flavonoids.
Pharma Action Dentifrices 		J Clin Dent 2000;11(2):53-9
1-(2,4-dioxo-5-fluoro-(1H,3H)-pyrimidin-1-yl)-2-(2,3-dihydroxy-2-buten-4-olidylidene)ethane  0   Ascorbic Acid/*analogs & derivatives Fluorouracil/*analogs & derivatives. J Med Chem 2000 Dec 14;43(25):4806-11
6-O-palmitol-ascorbate-2-O-phosphate  0   Ascorbic Acid/*analogs & derivatives. Anticancer Res 1999 Sep-Oct;19(5B):4321-5
6-deoxy-6-iodoascorbic acid  0   Ascorbic Acid. J Biol Chem 1999 Jul 29;42(15):23215-22
magnum C  0   *Ascorbic Acid *Flavonoids Drug Combinations. Vopr Pitan 1999;68(3):9-11
docosahexaenoylascorbic acid  0   *Docosahexaenoic Acids Ascorbic Acid/*analogs & derivatives. Nippon Yakurigaku Zasshi 1997 Oct;110 Suppl 1:171P-176P
6-O-phenylascorbic acid  85766-69-4   Ascorbic Acid/*analogs & derivatives. Biophys J 1997 Sep;73(3):1645-54
2-O-(5-hydroxy-4H-pyran-4-one-2-methyl)ascorbic acid  0   Ascorbic Acid/*analogs & derivatives Monophenol Monooxygenase/antagonists & inhibitors. Chem Pharm Bull (Tokyo) 1996 Sep;44(9):1647-55
3-O-((tocopheryloxy)-2-hydroxypropyl)ascorbic acid  0   Ascorbic Acid/*analogs & derivatives Monophenol Monooxygenase/antagonists & inhibitors. Chem Pharm Bull (Tokyo) 1996 Sep;44(9):1647-55
alpha tocopherol, ascorbic acid, betacarotene, buphenine hydrochloride drug combination  0   *Ascorbic Acid *Nylidrin *beta Carotene Drug Combinations Vitamin E/*analogs & derivatives. Ophthalmologica 1995;209(6):302-5
vanadium diascorbate  0   *Organometallic Compounds Ascorbic Acid/*analogs & derivatives Vanadium. Biochem Biophys Res Commun 1995 Aug 4;213(1):289-94
6-amino-6-deoxyascorbic acid  0   Ascorbic Acid/*analogs & derivatives. J Cancer Res Clin Oncol 1995;121(2):98-102
6-chloro-6-deoxyascorbic acid  62983-43-1   Ascorbic Acid/*analogs & derivatives. Int J Radiat Biol 1994 Aug;66(2):123-31
6-S-n-hexadecyl-3-O-methyl-6-thioascorbic acid  0   Ascorbic Acid/*analogs & derivatives. Mol Pharmacol 1994 May;45(5):815-25
6-S-hexadecyl-2-methoxythioascorbic acid  8065-53-0   Ascorbic Acid/*analogs & derivatives. Mol Pharmacol 1994 May;45(5):815-25
ascorbic acid-2-O-glucuronide  0   *Glucuronates Ascorbic Acid/*analogs & derivatives. Biochim Biophys Acta 1994 Apr 21;1199(30:305-10
ascorbic acid 2-(11-oxoolean-12-en-29-oic acid ethyl ester 3-yl-phosphate)  145079-98-7   Ascorbic Acid/*analogs & derivatives Glycyrrhetinic Acid/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1993 Nov;82(2):151-66
hex-2-enaro-1,4-lactone ethyl ester  146623-27-0   Ascorbic Acid/*analogs & derivatives. Int J Vitam Nutr Res 1993;63(3):208-11
ascorbate-2-polyphosphate  0   *Organophosphorus Compounds Ascorbic Acid/*analogs & derivatives. Int J Vitamin Nutr Res 1993;63(1):63-4
1'-ethylascorbigen  110326-15-3   *Indoles Ascorbic Acid/*analogs & derivatives. Biochem Biophys Res Commun 1993 Feb 15;190(3):895-900
6-deoxy-6-fluoroascorbic acid  142474-58-6   Ascorbic Acid/*analogs & derivatives Fluorine Radioisotopes. Int J Rad Appl Instrum (A) 1992 May;43(5):633-9
1'-methylascorbigen  92557-61-4   *Indoles Ascorbic Acid/*analogs & derivatives. J Antimicrob Chemother 1991 Dec;28(6):935-6
vicedrin  0   *Ascorbic Acid *Ephedrine *Phenacetin Drug Combinations. Cesk Pediatr 1991;46(2):98
zilascorb  20664-60-2   *Benzylidene Compounds Ascorbic Acid/*analogs & derivatives.
Pharma Action Antineoplastic Agents ; Antioxidants 		Anticancer Res 1991;11(3):1077
calcium ascorbate  5743-27-1   *Ascorbic Acid. Life Sci 1991;48(23):2275
6-deoxy-6-bromoascorbic acid  62983-44-2   Ascorbic Acid/*analogs & derivatives. Res Exp Med (Berl) 1990;190(6):443
tetramethylreductic acid  1889-96-9   Ascorbic Acid/*analogs & derivatives. Acta Crystallogr C 1990;46(Pt 9):1671
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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