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Ophthalmic Solutions

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Definition: Sterile solutions, essentially free from foreign particles and suitably compounded and dispensed, for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS. (From Dorland, 27th ed)  sterile solutions for instillation into the eyes: not for solutions for cleaning eyeglass lenses (    Other names Tears, Artificial; Eyedrops; Artificial Tears; Solutions, Ophthalmic; Drops, Eye; Eye Drops
Substances having this pharmacologic action: carbopol 940; hypromellose; tetrahydrozoline; Plasma-lyte 148; antazoline sulfate, naphazoline mononitrate drug combination
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
perfluorobutylbutane  0   *Fluorocarbons Ophthalmic Solutions. Graefes Arch Clin Exp Ophthalmol. 2004 Mar;242(3):218-22
diphoterine  0   Organic Chemicals Buffers Ophthalmic Solutions. Burns 2002 Nov;28(7):670-3
diquafosol  0 diuridine 5'-(pentahydrogen tetraphosphate) tetrasodium salt  *Polyphosphates *Uracil Nucleotides Ophthalmic Solutions Receptors, Purinergic P2/agonists. J Appl Physiol 1999 Dec;7(6):2191-6
proxopheline  0   *Clonidine *Oxadiazoles Drug Combinations Glaucoma Ophthalmic Solutions. Vestn Oftalmol 1998 May-Jun;114(3):3-4
BBS Plus  0   Bicarbonates Glutathione Sodium Chloride Isotonic Solutions Ophthalmic Solutions. Acta Ophthalmol Scand 1995 Dec;73(6):521-4
Opeguard MA  117925-70-9   Bicarbonates Glutathione Sodium Chloride Isotonic Solutions Ophthalmic Solutions. Acta Opthalmol Scand 1995 Dec;73(6):521-4
SDZ GLC 756  0   *Quinolines Ophthalmic Solutions Receptors, Dopamine D1/antagonists & inhibitors Receptors, Dopamine D2/agonists. Jpn J Ophthalmol 1996;40(2):167-73
leocaine  0   *Ethyl Ethers Ophthalmic Solutions. Vestn Oftalmol 1995 Oct-Dec;111(4):19-21
Lubrithal  0   *Acrylates *Polymers Sucrose/*analogs & derivatives Ophthalmic Solutions. Doc Ophthalmol 1994;88(2):187-94
monomethyl trisilanol sodium orthohydroxybenzoate  0   *Salicylic Acids *Organosilicon Compounds Ophthalmic Solutions. Dev Ophthalmol 1994;26:40-6
proxodolol  158446-41-4   *Oxadiazoles Ophthalmic Solutions. Eksp Klin Farmakol 1994 May-Jun;57(3):30-3
Lacrozym  0   *Muramidase *Citric Acid Drug Combinations Ophthalmic Solutions. Acta Ophthalmol (Copenh) 1993 Dec;71(6):836-8
OF 4647  0   Organic Chemicals Ophthalmic Solutions. Vestn Oftalmol 1993 Jan-Feb;109(1):3-6
OF 4680  0   *Taurine *Thymol Drug Combinations Ophthalmic Solutions. Vestn Oftalmol 1993 Jan-Feb;109(1):3-6
SK&F 84210  68981-32-8   *Aniline Compounds *Pyrones Hypersensitivity/drug therapy Ophthalmic Solutions. J Med Chem 1991;34(1):392
vistagan-liquifilm  0   *Benzalkonium Compounds *Levobunolol Ophthalmic Solutions. Klin Oczna 1989;91(6):163
Optrex Eye Lotion  0   *Allantoin *Boric Acids *Chlorobutanol *Salicylic Acids Drug Combinations Ophthalmic Solutions. Br J Clin Pract 1989;43(10):357
Vitasic  138331-07-4   *Nucleosides *Nucleotides Ophthalmic Solutions. Ophthalmologica 1989;199(2-3):100
L 40 irrigating solution  0   *Dextrans *Sodium Chloride Drug Combinations Ophthalmic Solutions. Cornea 1986;4(4):210
vidisic  126371-26-4   *Acrylates Ophthalmic Solutions. Klin Monasbl Augenheilkd 1986;189)1):51
Compound 764-1  0   *Drugs, Chinese Herbal Ophthalmic Solutions. J Tradit Chin Med 1985;5(1):9
amlexanox  68302-57-8 5H-(1)Benzopyrano(2,3-b)pyridine-3-carboxylic acid, 2-amino-7-(1-methylethyl)-5-oxo  *Aminopyridines Ophthalmic Solutions.
Pharma Action Anti-Allergic Agents
Int Arch Allergy Appl Immunol 1985;77(3):315AMLEXANOX; APHTHASOL
Gel Tears acrylic resin  0   *Acrylic Resins Gels Ophthalmic Solutions. Ophthalmology 1984;91(10):1199
pentosan sulfuric polyester, phenylephrine, thiomersal drug combination  0   *Pentosan Sulfuric Polyester *Phenylephrine *Thimerosal Drug Combinations Ophthalmic Solutions. Bull Soc Ophtamol Fr 1983;83(2):213
suprexon  0   *Epinephrine *Guanethidine Drug Combinations Ophthalmic Solutions. Klin Monatsbl Augenheilkd 1983;183(1):17
etaretin  0   *Phospholipids Ophthalmic Solutions. Klin Monatsbl Augenheilkd 1983;182(6):570
micronomicin  52093-21-7 D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy  *Aminoglycosides Benzalkonium Compounds Irritants Ophthalmic Solutions.
Pharma Action Anti-Bacterial Agents
Antibiotiki 21(11):1033;1976; J Antibiot (Tokyo) 28(1):21;1975; J Jpn Assoc Infect Dis 52(5):146;1978; Jpn J Antibiot 1983;36(1):150; Jpn J Antibiot 30(6):362;1977; Jpn J Antibiot 30(6):386-432;1977; Jpn J Antibiot 31(3):149;1978; Nippon Ganka Gakkai Zasshi 83(5):405;1979
neoparyl-framycetin  0   *Framycetin Drug Combinations Heparin/*analogs & derivatives Phenylephrine/*analogs & derivatives Ophthalmic Solutions. Bull Soc Ophthalmol Fr 1982;82(6-7):823
Correctol eyedrops  80106-39-4   Electrolytes Sodium Chloride Ophthalmic Solutions. Bull Soc Ophtalmol Fr 1981;81(1):47
phacolysin  0   *Acridines Ophthalmic Solutions. Klin Oczna 1980;82(4):219
conjunctisan A  0   *Eye Proteins *Tissue Extracts Drug Combinations Ophthalmic Solutions. Klin Monatsbl Augenheilkd 1979;175(6):795
Piloplex  62783-28-2 2-Propenoic acid, 2-methyl-, dodecyl ester, polymer with 2-propenoic acid, compd. with (3S-cis)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone  *Pilocarpine Delayed-Action Preparations Ophthalmic Solutions. Br J Ophthalmol 63(1):45;1979
metariboadenosine triphosphorous  0   *Adenosine Triphosphate *Riboflavin Drug Combinations Uracil/*analogs & derivatives Ophthalmic Solutions. Oftalmol Zh 1977;32(7):548-9
glutathione-bicarbonate-Ringer solution  0   *Bicarbonates *Glutathione Drug Combinations Adenosine Ophthalmic Solutions. Am J Ophthalmol 82(4):594;1976BSS PLUS
prednefrin  78393-43-8 Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11beta)-, mixt. with (R)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol hydrochloride  *Phenylephrine *Prednisolone Drug Combinations Administration, Topical Ophthalmic Solutions. Ann Ophthalmol 6(12):1263;1974
oxybiciron  78371-68-3 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-, mixture with 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphtha  *Imidazoles *Oxytetracycline Drug Combinations Ophthalmic Solutions. Med Welt 24(27/28):1145;1973
adsorbobase  53986-33-7   *Povidone Ophthalmic Solutions. Ann Ophthalmol 9(4):427;1977; Eye, Ear, Nose, Throat Mont 53(1):54;1974
dexamethasone, tramazoline drug combination  0   *Dexamethasone Isonicotinate *Imidazoles Drug Combinations Ophthalmic Solutions. Z Allgemein Med 49(7):330;1973
Predni-opthiole  0   *Chloramphenicol *Prednisone Drug Combinations Ophthalmic Solutions.
Predni aquos opthiole  8024-67-7   *Neomycin *Prednisolone Drug Combinations Ophthalmic Solutions. NEO-HYDELTRASOL; POLY-PRED; NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE; MYTREX A; NEO-DELTA-CORTEF
chlorophyllypt  12750-97-9   *Chlorophyll *Plant Extracts Drug Combinations Ophthalmic Solutions. Mikrobiol Zh 40(4):453;1978; Oftalmol Zh 27(8):623;1972; Ped Akush Ginekol 1:36;1978; Pediatr Akush Ginekol 1979;(5):55; Vshn Nos Gorl Bolezn 3:85;1977; Zdravookhr Kirg 1979;(6):8; Zh Vshn Nos Gorl Bolezn 6:79;1975
hydroxyethylcellulose  9004-62-0 cellulose, 2-hydroxyethyl ether  Cellulose/*analogs & derivatives Ophthalmic Solutions Saliva, Artificial. Ann Ophthalmol 4(11):1001;1972; Arch Ophthalmol 95:247;1977; J Pharm Sci 67(7):935;1978; Res Vet Sci 21:356;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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