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Guanethidine

More information in Books or onNLM PubMed
Definition: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.     
Pharmacological Action Adrenergic Agents; Antihypertensive Agents; Sympatholytics 		Other names Sulfate, Guanethidine; Monosulfate, Guanethidine; Oktadin; Octadine; Isobarin; Guanethidine Sulfate (2:1), 14C-Labeled; Guanethidine Sulfate (2:1); Guanethidine Sulfate (1:2); Guanethidine Sulfate (1:1); Ismelin; Guanethidine Sulfate; Guanethidine Monosulfate; ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidineDrugs* : ISMELIN; GUANETHIDINE MONOSULFATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dichloro(guanethidine)platinum(II)  84152-28-3   *Organoplatinum Compounds Guanethidine/*analogs & derivatives. J Antimicrob Chemother 1997 Jul;40(1):47-57
suprexon  0   *Epinephrine *Guanethidine Drug Combinations Ophthalmic Solutions. Klin Monatsbl Augenheilkd 1983;183(1):17
guanethidine N-oxide  22388-79-0   Guanethidine/*analogs & derivatives. Biochem Biophys Res Commun 1983;112(2):444
Esimil  8015-24-5 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide, compd. with (2-(hexahydro-1(2H)-azocinyl)ethyl)guanidine sulfate (1:2:1)  *Guanethidine *Hydrochlorothiazide Drug Combinations. G Clin Med 1982;63(4):270ESIMIL
guanazodine  32059-15-7 ((octahydro-2-azocinyl)methyl)guanidine  Guanethidine/*analogs & derivatives. Acta Med Acad Sci Hung 33(4):339;1976; Acta Pharm Hung 48(2):76;1978; Arzneim Forsch 27(11):2163;1977; Folia Pharmacol Jpn 72(7):837;1976; Int J Clin Pharmacol 8(2):111;1973; J Pharm Soc Jpn 96(9):1049;1976; Sov Med 1:86;1978; Ther Hung 25(4):134;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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