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phaclofen

under Baclofen
More information in Books or onNLM PubMed
More on Baclofen Definition: A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.      Other names Chlorophenyl GABA; Baclophen; PMSBaclofen; PMS Baclofen; NuBaclo; Nu Pharm Brand of Baclofen; Nu Baclo; GenBaclofen; Gen Baclofen; GABA, Chlorophenyl; Ciba Geigy Brand of Baclofen; CIBA34,647BA; Baclof+¿neIrex; Baclof+¿ne Irex; Baclofen Pharmascience Brand; Baclofen Nu-Pharm Brand; Baclofen Novartis Brand; Baclofen Medtronic Brand; Baclofen Isis Brand; Baclofen Irex Brand Drugs: LIORESALGABLOFEN; KEMSTRO; BACLOFEN;
SubstanceCAS Registry & nameCategoriesSourceDrugs*
phaclofen [ beta-(4-chlorophenyl)-3-aminopropylphosphonic acid ]
  peripheral & central baclofen & GABA antagonist; structure given in first source 		108351-35-5   Baclofen/*analogs & derivatives
Pharma Action GABA Antagonists 		Brain Res 1987;405(1):150

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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