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(3-aminopropyl)(n-butyl)phosphinic acid

under Organophosphorus Compounds
More information in Books or onNLM PubMed
More on Organophosphorus Compounds Definition: Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.  DF: ORGANOPHOSPHORUS CPDS    Other names Compounds, Organopyrophosphorus; Compounds, Organophosphorus; Organopyrophosphorus Compounds
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(3-aminopropyl)(n-butyl)phosphinic acid [ CGP 36742,CGP36742,3-aminopropyl-n-butyl phosphinic acid,CGP-36742,SGS-742,SGS742 ]
  interacts preferably with GABA-B RECEPTORS (IC50=38 ++M) and GABA-C receptors (IC50=62 ++M) over GABA-A RECEPTORS (IC50=508 ++M)
145537-81-1   *Organophosphorus Compounds
Pharma Action Neuroprotective Agents; GABA Antagonists
Biochem Pharm 2004 Oct 15; 68(8):1479-87; Eur J Pharmacol 1992 Nov 17;223(2-3):193-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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