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Phosphonic Acids
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ψ
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| Inorganic or organic derivatives of phosphonic acid with the general formula ROP(OH)2 or RP(=O)(OH)2. The tautomeric form of this compound (P(OH)3) is PHOSPHOROUS ACIDS. Nucleoside phosphonates have a phosphate-carbon bond that is more resistant to enzym
| do not confuse with PHOSPHINIC ACIDS; for nucleoside phosphonates coordinate with PURINES or PYRIMIDINES
| Other names Esters, Phosphonic Acid; Acids, Phosphonic; Acid Esters, Phosphonic; Phosphonic Acid Esters; Phosphonates
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| Substance | CAS Registry & name | Categories | Source | Drugs*
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| tenofovir [ (R)-9-(2-phosphonylmethoxypropyl)adenine,9-(2-phosphonomethoxypropyl)adenine,9-PMPA,9-(2-phosphonylmethoxypropyl)adenine,9-(2-phosphonylmethoxypropyl)adenine, (+-)-isomer,9-(2-phosphonylmethoxypropyl)adenine, (S)-isomer,9-(2-phosphonylmethoxypropyl)adenine, (R)-isomer ]
| 107021-12-5
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*Phosphonic AcidsAdenine/*analogs & derivatives
Pharma Action Reverse Transcriptase Inhibitors; Anti-HIV Agents
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Lancet 1995 Dec 2;346(8988):1482
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