Definition: Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.
SU 5416 [ 3-(2,4-dimethylpyrrol-5-yl)methylidene-indolin-2-one,SU-5416,SU5416,Semaxinib ] SU5416, a synthetic compound, is a potent and selective inhibitor of the Flk-1/KDR receptor tyrosine kinase that is presently under evaluation in phase I trial studies for the treatment of human cance