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Aflatoxins

More information in Books or onNLM PubMed
Definition: Furano-furano-benzopyrans that are produced by ASPERGILLUS from STERIGMATOCYSTIN. They are structurally related to COUMARINS and easily oxidized to an epoxide form to become ALKYLATING AGENTS. Members of the group include AFLATOXIN B1; aflatoxin B2, aflatoxin G1, aflatoxin G2; AFLATOXIN M1; and aflatoxin M2.  /antag permitted but consider also ANTITOXINS   
Pharmacological Action Poisons
Examples Aflatoxin B1; Aflatoxin M1
Other names Aflatoxin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
austocystin D  0   *Aflatoxins. J Nat Prod. 2011 Apr 25;74(4):567-73
AFLR-2 protein, Aspergillus parasiticus  0   *DNA-Binding Proteins *Fungal Proteins Aflatoxins. Biochim Biophys Acta 2002 Jul 19;1576(3):316-23
4, 6-dihydroxy-5-methoxy-6a-methylcyclohexa(de)indano(7, 6-e)cyclopenta(c)2H-pyran-1,9-dione  0   *Aflatoxins. J Nat Prod 2000 Dec;63(12):1677-8
AFLR protein, Aspergillus  0   *DNA-Binding Proteins *Fungal Proteins *Transcription Factors Aflatoxins Zinc Fingers. Fungal Genet Biol 1998 Apr;23(3):279-87
aflatoxin-albumin adduct  0   *Aflatoxins *Albumins. Mutat Res 1996 Feb 1;349(2):209-17
omtA protein, Aspergillus  EC 2.1.1.-   *Fungal Proteins *Methyltransferases Aflatoxins. Gene 1995 Sep 12;163(1):121-5
aflatoxin G1 9,10-epoxide  120476-24-6   *Aflatoxins. Chem Res Toxicol 1990;3(3):254
aflatoxin P1  32215-02-4   *Aflatoxins. Toxicology 1984;32(2):145
aflatoxin Q2a-bovine serum albumin  0   *Aflatoxins *Serum Albumin, Bovine Antigens. Appl Environ Microbiol 1984;47(3):526
aflatoxin Q2a  89989-32-2   *Aflatoxins Antigens. Appl Environ Microbiol 1984;47(3):526
aflatoxin A1-hemisuccinate  0   *Aflatoxins Antigens. Appl Environ Microbiol 1984;47(3):526
aflatoxicol M1  64330-03-6   *Aflatoxins. Food Chem Toxicol 1983;21(5):557
aflatoxin Q1  52819-96-2   *Aflatoxins. Cancer Res 1982;42(3):1120
aflatoxin M2  6885-57-0   *Aflatoxins. Mycopathologia 1981;74(1):3
aflatoxin G2  7241-98-7   *Aflatoxins. IARC Sci Publ 1980;37:1
aflatoxin B2  22040-96-6   *Aflatoxins. IARC Sci Publ 1980;37:1
aflatoxin D1  52373-83-8   *Aflatoxins Mycotoxins. Experientia 1981;37(1):16
aflatoxin G1  1165-39-5   *Aflatoxins. Z Lebensm Unters Forsh 1980;171(5):341
dihydroaflatoxin  0   *Aflatoxins. Food Cosmet Toxicol 1979;17(5):501
aflatoxicol  29611-03-8   *Aflatoxins.
Pharma Action Carcinogens
Cancer Res 36(6):2040;1976; Cancer Res 37:1016;1977; Fd Cosmet Toxicol 1979;17(5):481; J Agr Food Chem 25(2):437;1977; Science 200(4339):325;1978
2,3-dihydrodiolaflatoxin B  0   *Aflatoxins. FEBS Lett 36(3):261;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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